[Disseminated peritoneal leiomyomatosis: apropos of a case with immunohistochemical study].

Abstract

We report one case of leiomyomatosis peritonealis disseminata in a 40-year-old woman, G4P4, who never used oral contraceptives. She had relapsing uterine leiomyoma resected twice by hysteroscopy. Clinical findings and imaging studies concluded to peritoneal carcinomatosis. The patient had hysterectomy, salpingo-oophorectomy, omentectomy and resection of an intestinal segment which surface is studied with firm nodules ranging in size from 1 to 50 mm. Microscopic examination showed a smooth-muscle cell proliferation with no mitosis, no atypia and no necrosis. Immunohistochemical analysis showed diffuse and strong labeling for progesterone receptors and weak labeling for estrogen receptors. The patient is well 16 months later. In the literature, over than 100 cases are reported, eight were malignant.

• Authors: S Trabelsi, K Mrad, M Driss, K Ben Romdhane
• Journal: Gynecologie, obstetrique & fertilite (Gynecol Obstet Fertil) Vol. 29 Issue 10 Pg. 692-5 (Oct 2001) ISSN: 1297-9589 [Print] France
• Vernacular Title: Léiomyomatose péritonéale disséminée: à propos d'un cas avec étude immunohistochimique.
• PMID: 11732435 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Receptors, Estrogen
• Receptors, Progesterone

Topics

• Adult
• Fallopian Tubes (surgery)
• Female
• Humans
• Hysterectomy
• Immunohistochemistry
• Leiomyoma (pathology, surgery)
• Leiomyomatosis (diagnosis, pathology, surgery)
• Neoplasm Recurrence, Local
• Omentum (surgery)
• Ovariectomy
• Peritoneal Neoplasms (diagnosis, pathology, surgery)
• Receptors, Estrogen (analysis)
• Receptors, Progesterone (analysis)
• Uterine Neoplasms (pathology, surgery)