Abstract | OBJECTIVE: DESIGN AND METHODS: RESULTS: The cortisol/ cortisone ratios were significantly higher in patients with Cushing's disease (13.9 +/- 1.1), adrenal tumors (11.5 +/- 2.3), and in healthy volunteers after ACTH stimulation (14.1 +/- 2.0) than in untreated controls (6.0 +/- 0.5) (P < 0.001, P < 0.05, and P < 0.001, respectively). Similar differences were seen for cortisol plasma concentrations, whereas cortisone concentrations did not differ among the groups. CONCLUSIONS:
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Authors | J Dötsch, H G Dörr, G K Stalla, W G Sippell |
Journal | Steroids
(Steroids)
Vol. 66
Issue 11
Pg. 817-20
(Nov 2001)
ISSN: 0039-128X [Print] United States |
PMID | 11576621
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
|
Chemical References |
- Mineralocorticoids
- Adrenocorticotropic Hormone
- Hydroxysteroid Dehydrogenases
- 11-beta-Hydroxysteroid Dehydrogenases
- Cortisone
- Hydrocortisone
|
Topics |
- 11-beta-Hydroxysteroid Dehydrogenases
- Adrenal Gland Neoplasms
(complications)
- Adrenocortical Hyperfunction
(blood, etiology)
- Adrenocorticotropic Hormone
(administration & dosage, blood)
- Adult
- Aged
- Cortisone
(blood)
- Cushing Syndrome
(blood, complications)
- Female
- Humans
- Hydrocortisone
(agonists, blood)
- Hydroxysteroid Dehydrogenases
(drug effects, metabolism)
- Hypertension
(etiology)
- Male
- Matched-Pair Analysis
- Middle Aged
- Mineralocorticoids
(blood)
- Stimulation, Chemical
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