Subcorneal pustular dermatosis and IgA lambda myeloma: a uncommon association but probably not coincidental.

Abstract

The present report deals with a case of subcorneal pustular dermatosis (SCPD) associated with IgAlambda myeloma and reviews the literature for similar cases. Three relevant points arise from this case: the association of the dermatosis with an IgAlambda myeloma that, as far as we know, has been described only three times previously; the longest period of time between the onset of the dermatosis and that of the myelopathy observed up to now; the good therapeutic response to etretinate, useful in the management of severe recalcitrant forms of SCPD.

• Authors: M Vaccaro, S P Cannavò, B Guarneri
• Journal: European journal of dermatology : EJD (Eur J Dermatol) Vol. 9 Issue 8 Pg. 644-6 (Dec 1999) ISSN: 1167-1122 [Print] France
• PMID: 10586134 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin A
• Immunoglobulin lambda-Chains
• Etretinate

Topics

• Aged
• Etretinate (therapeutic use)
• Humans
• Immunoglobulin A (analysis)
• Immunoglobulin lambda-Chains
• Male
• Multiple Myeloma (complications, immunology)
• Skin Diseases, Vesiculobullous (complications, drug therapy, pathology)