APOBEC-3G Deaminase
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
Also Known As:
APOBEC-3G Protein; APOBEC-3G dC-dU Editing Enzyme; APOBEC-Related Cytidine Deaminase; APOBEC-Related Protein; APOBEC3G Deaminase; APOBEC3G Protein; CEM15 Protein; APOBEC 3G Deaminase; APOBEC 3G Protein; APOBEC 3G dC dU Editing Enzyme; APOBEC Related Cytidine Deaminase; APOBEC Related Protein; Cytidine Deaminase, APOBEC-Related; Deaminase, APOBEC-3G; Deaminase, APOBEC3G
Networked: 3
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Li, Zelin:
1 article
(03/2011)
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2. | Qiao, Xinhua:
1 article
(03/2011)
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3. | Zeng, Yi:
1 article
(03/2011)
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4. | Zhang, Wenjun:
1 article
(03/2011)
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5. | Kryworuchko, Marko:
1 article
(07/2008)
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6. | Kumar, Ashok:
1 article
(07/2008)
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7. | Sirskyj, Danylo:
1 article
(07/2008)
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8. | Thèze, Jacques:
1 article
(07/2008)
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9. | Kremer, Melanie:
1 article
(10/2006)
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10. | Martinez-Fernandez, Yolanda:
1 article
(10/2006)
|
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