japonicone A

09/01/2015 - "This study investigated the effects of japonicone A on the growth of non-small cell lung cancer (NSCLC) cell lines. "
09/01/2015 - "Japonicone A inhibits the growth of non-small cell lung cancer cells via mitochondria-mediated pathways."

11/01/2019 - "In addition, based on the GSE85871 dataset and inhibitory assay, the study identified a natural compound, Japonicone A, which may reduce the proliferation of breast cancer cells by inhibiting the expression of RAD54B. "

09/01/2015 - "In vivo, japonicone A suppressed tumor growth via the same mechanism as that observed in vitro. "
06/01/2013 - "Moreover, Japonicone A inhibited local growth and dissemination of cancer cells to multiple organs in vivo. "
06/01/2013 - "Japonicone A killed cancer cells but had low cytotoxicity to normal cells. "
06/01/2013 - "Various types of cancer and normal cells were exposed to Japonicone A for cytotoxicity screening, followed by determination of cell apoptosis and cell-cycle arrest. "
03/01/2014 - "One promising compound, Japonicone A, a dimeric sesquiterpene lactone from traditional herb Inula japonica, has displayed potent in vitro and in vivo anti-tumor activity against Burkitt's lymphoma. "

06/01/2013 - "Japonicone A exerts significant anticancer effects on Burkitt lymphoma cells in vitro and in vivo through targeting of the NF-κB signaling cascade. "
06/01/2013 - "Japonicone A suppresses growth of Burkitt lymphoma cells through its effect on NF-κB."
03/01/2014 - "One promising compound, Japonicone A, a dimeric sesquiterpene lactone from traditional herb Inula japonica, has displayed potent in vitro and in vivo anti-tumor activity against Burkitt's lymphoma. "

06/01/2013 - "Japonicone A inhibited the growth and proliferation of Raji, BJAB, and NAMALWA lymphoma cells and resulted in G2-M phase arrest and apoptosis. "
06/01/2013 - "These results highlight the potential of Japonicone A as a chemotherapeutic agent and warrant its development as a therapy for lymphomas."