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TFA-12

synthetic compound; structure in first source

Also Known As:

TFA-12 tocopherol derivative

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocopherols: 1861
        TFA-12: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Vitamin E: 8680
        Tocopherols: 1861
        TFA-12: 1

Experts

1.	Baron-Van Evercooren, Anne: 1 article (07/2013)
2.	Blanchard, Benoit: 1 article (07/2013)
3.	Caillava, Céline: 1 article (07/2013)
4.	Coowar, Djalil: 1 article (07/2013)
5.	Frah, Magali: 1 article (07/2013)
6.	Garcia, Corina: 1 article (07/2013)
7.	Grandbarbe, Luc: 1 article (07/2013)
8.	Heurtaux, Tony: 1 article (07/2013)
9.	Heuschling, Paul: 1 article (07/2013)
10.	Kerninon, Christophe: 1 article (07/2013)

Related Diseases

1.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/10/2013 - "Here, we examined the ability of TFA-12, a new synthetic compound belonging to tocopherol long-chain fatty alcohols, to promote oligodendrocyte regeneration and remyelination in experimental models of MS. We showed that TFA-12 significantly ameliorates neurological deficit and severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (EAE) in mice. "
2.	Multiple Sclerosis 07/10/2013 - "Tocopherol derivative TFA-12 promotes myelin repair in experimental models of multiple sclerosis."
3.	Inflammation (Inflammations) 07/10/2013 - "Histological evaluation of mouse EAE spinal cords showed that TFA-12 treatment reduces inflammation, astrogliosis, and myelin loss. "
4.	Gliosis 07/10/2013 - "Histological evaluation of mouse EAE spinal cords showed that TFA-12 treatment reduces inflammation, astrogliosis, and myelin loss. "

Related Drugs and Biologics

1.	Myelin-Oligodendrocyte Glycoprotein
2.	Tocopherols (Tocopherol)
3.	Fatty Alcohols