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nodosin

has anti-inflammatory activity; isolated from Isodon serra; structure in first source

Networked: 5 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - nodosin: 5

Experts

1.	Bae, Eun Seo: 1 article (09/2020)
2.	Byun, Woong Sub: 1 article (09/2020)
3.	Chin, Young-Won: 1 article (09/2020)
4.	Kim, Dong-Hwa: 1 article (09/2020)
5.	Kim, Young-Mi: 1 article (09/2020)
6.	Lee, Sang Kook: 1 article (09/2020)
7.	Park, Hyen Joo: 1 article (09/2020)
8.	Isobe, Takahiko: 1 article (08/2012)
9.	Kubo, Isao: 1 article (08/2012)
10.	Nitoda, Teruhiko: 1 article (08/2012)

Related Diseases

1.	Reperfusion Injury 04/01/2012 - "This study suggests that preconditioning with Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation." 04/01/2012 - "Preconditioning donor liver with Nodosin perfusion lessens rat ischemia reperfusion injury via heme oxygenase-1 upregulation."
2.	Colonic Neoplasms (Colon Cancer) 09/01/2020 - "In the present study, we found that Nodosin, an ent-kaurene diterpenoid isolated from Isodon serra, effectively inhibits the proliferation of human colon cancer HCT116 cells. " 09/01/2020 - "Anti-Proliferative Activity of Nodosin, a Diterpenoid from Isodon serra, via Regulation of Wnt/β-Catenin Signaling Pathways in Human Colon Cancer Cells."
3.	Urinary Bladder Neoplasms (Bladder Cancer) 01/01/2022 - "This study is the first to report basic research findings on the network pharmacological mechanism of cytotoxicity of bladder cancer cells by nodosin, providing novel evidence for the application of nodosin in the field of oncology; however, other mechanisms may be involved in the effects of nodosin for further research. " 01/01/2022 - "Nodosin, found in Isodon serra (Maxim.) Kudo (known as Xihuangcao), may inhibit bladder cancer cells. " 01/01/2022 - "Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo." 01/01/2022 - "In vivo, nodosin inhibited bladder cancer cell growth in a model of xenograft tumor in nude mice. "
4.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2022 - "Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo." 09/01/2020 - "These findings suggest that the anti-proliferative activity of Nodosin in colorectal cancer cells might in part be associated with the regulation of Wnt/β-catenin signaling pathway."
5.	Neoplasms (Cancer) 01/01/2022 - "In vivo, we found that nodosin inhibited tumor growth and induced cells to undergo apoptosis and autophagy without significant toxic effects. " 01/01/2022 - "In vivo, nodosin inhibited bladder cancer cell growth in a model of xenograft tumor in nude mice. "

Related Drugs and Biologics

1.	Kaurane Diterpenes
2.	Diterpenes
3.	Heme Oxygenase-1
4.	Catenins
5.	oridonin

Related Therapies and Procedures

1.	Liver Transplantation