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2-n-nonyl-1,3-dioxolane

structure in first source

Also Known As:

2-SEPA; SEPA 0009

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxoles
    - Dioxolanes: 3
      - 2-n-nonyl-1,3-dioxolane: 2

Experts

1.	Chan, Tom: 1 article (01/2005)
2.	Fuhrman, Jill: 1 article (01/2005)
3.	Hansen, Laura A: 1 article (01/2005)
4.	Repertinger, Susan: 1 article (01/2005)
5.	Shafer, Laura: 1 article (01/2005)
6.	Barbadillo, Sherry: 1 article (01/2003)
7.	Chan, Thomas C K: 1 article (01/2003)
8.	Hui, Xiaoying: 1 article (01/2003)
9.	Lee, Christine: 1 article (01/2003)
10.	Maibach, Howard I: 1 article (01/2003)

Related Diseases

1.	Mycoses (Diseases, Fungus) 01/01/2003 - "This study determines the enhancing effects of 2-n-nonyl-1,3-dioxolane on the penetration of econazole, an antifungal drug, into the deeper layers of the human nail where fungal infection resides. "
2.	Wounds and Injuries (Trauma) 01/01/2005 - "The irritation was accompanied by increased proliferation, increased apoptosis, and expression of the wound-associated keratin 6. High-dose SEPA 0009 induced squamous papillomas in Tg.AC, but not in nontransgenic mice, by 6 weeks. "
3.	Papilloma (Papillomatosis) 01/01/2005 - "In contrast, low-dose SEPA 0009 was not irritating to the skin and did not induce papillomas. " 01/01/2005 - "In mice treated with the high dose SEPA 0009, transgene expression was detected in papillomas at week 9, well after the onset of skin irritation and hyperplasia. " 01/01/2005 - "The irritation was accompanied by increased proliferation, increased apoptosis, and expression of the wound-associated keratin 6. High-dose SEPA 0009 induced squamous papillomas in Tg.AC, but not in nontransgenic mice, by 6 weeks. "
4.	Hyperplasia 01/01/2005 - "In mice treated with the high dose SEPA 0009, transgene expression was detected in papillomas at week 9, well after the onset of skin irritation and hyperplasia. "
5.	Body Weight (Weight, Body) 01/01/2005 - "Fifty mg SEPA 0009/kg body weight, 1500 mg SEPA 0009/kg body weight, or the vehicle alone was applied daily to the skin of Tg.AC mice. "

Related Drugs and Biologics

1.	Econazole
2.	Keratin-6 (Keratin 6A)