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Econazole

An imidazole derivative that is commonly used as a topical antifungal agent.

Also Known As:

Econazole Nitrate; Ekonazole; Gyno-Pervaryl 150; Gyno-Pevaril; Gyno-Pevaryl; Pevaryl; Gyno Pervaryl 150; Gyno Pevaril; Gyno Pevaryl; GynoPevaril; Nitrate, Econazole; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-

Networked: 163 relevant articles (17 outcomes, 43 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - Econazole: 163
        Pevisone: 2
        econazole sulfosalicylate

Experts

1.	Ahmad, Zahoor: 4 articles (02/2008 - 05/2006)
2.	Sharma, Sadhna: 4 articles (02/2008 - 05/2006)
3.	Khuller, G K: 3 articles (09/2015 - 08/2006)
4.	Zhang, Yicheng: 3 articles (03/2008 - 04/2002)
5.	Maibach, Howard I: 2 articles (11/2015 - 01/2003)
6.	Tur-Tur, Cristina: 2 articles (08/2015 - 04/2013)
7.	Giusiano, Gustavo: 2 articles (08/2015 - 04/2013)
8.	Carrillo-Muñoz, Alfonso Javier: 2 articles (08/2015 - 04/2013)
9.	Pathak, Kamla: 2 articles (05/2013 - 05/2012)
10.	Berger, Stuart A: 2 articles (03/2008 - 10/2002)

Related Diseases

1.	Candidiasis (Moniliasis) 01/01/1979 - "Pointing out the fact that there is a generalized increase in the incidence of vaginal candidiasis the authors describe a study involving a total of sixty-one patients to evaluate econazole in the treatment of the condition." 01/01/2014 - "This synergistic effect may markedly reduce the dose of econazole-nitrate required to treat candidiasis, thereby decreasing the econazole-nitrate toxic side effects. " 10/01/2011 - "By careful engineering of the rheological properties, in-situ thermosensitive gel formulations of econazole nitrate were prepared and were shown to be efficacious in the treatment of vaginal candidiasis." 02/17/1983 - "[Effectiveness of econazole on pregnant women with vulvo-vaginal candidiasis]." 07/01/1980 - "[Pevaryl in vaginal candidiasis. "
2.	Infection 04/01/1990 - "The antibacterial efficacy of econazole nitrate in interdigital toe web infections." 06/01/1982 - "A clinical study of econazole cream in the treatment of fungal skin infections." 09/23/1981 - "Econazole treatment of fungal infections: an open trial." 11/10/2015 - "The present overview focuses on novel nano-based formulation approaches used to improve econazole penetration through skin for treatment of superficial fungal infections. " 11/10/2015 - "Econazole is a commonly used azole antifungal in clinical treatment of superficial fungal infections. "
3.	Dermatomycoses (Dermatophytosis) 04/18/1979 - "In a controlled double-blind study, the author has comparatively studied the effectiveness and the safety of econazole and of a combination econazole-triamcinolon topically applied, on inflammatory dermatomycoses. " 09/15/1978 - "[Clinical experience in the management of dermatomycoses using the 1 per cent econazole-spray solution and the 1 per cent econazole-spray powder]." 04/25/1978 - "[Results of the clinical trial with pevaryl 1 % spray solution as therapeutic agent for local dermatomycoses (author's transl)]." 11/15/1977 - "[Topical use of econazole cream in dermatomycoses. " 02/15/1977 - "[Clinical testing of Econazole skin lotion and cream in dermatomycoses]."
4.	Vulvovaginal Candidiasis 10/15/1976 - "Three-day therapy of vulvovaginal candidiasis with econazole: a multicentric study comprising 996 cases." 01/01/2009 - "In patients with vulvovaginal candidiasis, sertaconazole as a single-dose ovule or tablet was effective in the eradication of Candida spp., and achieved both a more rapid and a higher cure rate compared with a triple dose of econazole. " 09/01/1990 - "In a randomized, single-blind, parallel study the safety and efficacy of 2% butoconazole nitrate cream used for 3 days were compared with those of 1% econazole nitrate cream used for 7 days at night in patients with vulvovaginal candidiasis. " 09/01/1990 - "A comparison of butoconazole nitrate cream with econazole nitrate cream for the treatment of vulvovaginal candidiasis." 07/01/1980 - "The therapeutic effectiveness of econazole and clotrimazole was evaluated in 178 women with clinical symptoms of vulvovaginal candidiasis and positive laboratory findings for Candida. "
5.	Tinea Pedis (Athlete's Foot) 11/01/1990 - "This study was conducted to determine the efficacy of twice-daily applications of econazole nitrate 1% for the treatment of tinea pedis within a typical podiatric practice. " 11/01/1990 - "Efficacy of twice-daily dosing of econazole nitrate 1% cream for tinea pedis." 07/01/2014 - "Econazole nitrate foam 1% for the treatment of tinea pedis: results from two double-blind, vehicle-controlled, phase 3 clinical trials." 07/01/2014 - "Econazole nitrate foam 1% presents a novel alternative for the management of tinea pedis." 07/01/2014 - "To evaluate econazole nitrate foam 1% versus foam vehicle for treatment of interdigital tinea pedis. "

Related Drugs and Biologics

1.	Clotrimazole (Lotrimin)
2.	Econazole
3.	Ketoconazole (Nizoral)
4.	Itraconazole (Sporanox)
5.	naftifine (naftifine hydrochloride)
6.	Miconazole (Monistat)
7.	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)
8.	Tolnaftate (Ting)
9.	Polymers
10.	imidazole

Related Therapies and Procedures

1.	Oral Administration
2.	Heterologous Transplantation (Xenotransplantation)
3.	Aftercare (After-Treatment)
4.	Drug Therapy (Chemotherapy)
5.	Transplants (Transplant)