SDZ 215-918

a cyclosporin derivative lacking immunosuppressive & peptidyl-prolyl-isomerase-inhibiting activity

Also Known As:

SDZ-215-918

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 09/01/1997 - "SDZ 215-918 does not bind to cyclophilins, the ubiquitous cyclosporin-binding proteins, but is a potent inhibitor of the mammalian P glycoprotein, a member of the ATP binding cassette transporter superfamily and the pump responsible for multidrug resistance in cancer and parasite cell lines. "

1.	Cyclophilins (Cyclophilin)
2.	Member 1 Subfamily B ATP Binding Cassette Transporter
3.	ATP-Binding Cassette Transporters (ABC Transporters)