NSC 100880
carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source
Also Known As:
NSC 100880, sodium salt, (S)-isomer; NSC-100880; Na-CPT
Networked: 1
relevant articles (1 outcomes,
0 trials/studies)
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Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Glioma (Gliomas)
03/01/2003
- " The authors have previously shown that local delivery of Na-CPT by implantable polymers prolongs survival in a rat intracranial glioma model. " 03/01/2003
- " Three of these analogs, 10,11-MD-20(RS)-CPT, 10,11-MD-20(S)-CPT-glycinate ester (Gly).HCl, and 9-amino-10,11-MD-20(S)-CPT-Gly, exhibit significantly greater antiproliferative activities than CPT, Na-CPT, or 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) against all three glioma cell lines. "
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2. | Brain Neoplasms (Brain Tumor)
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