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gynosaponin TN-1

produced from the enzymatic conversion of gyp XLVI by naringinase in Gynostamma pentaphallum; has cytotoxic effect on hepatoma cell lines

Also Known As:

gyp TN-1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - gynosaponin TN-1: 2

Experts

1.	Chen, Lianghua: 1 article (09/2018)
2.	Huang, Wen: 1 article (09/2018)
3.	Lin, Hetong: 1 article (09/2018)
4.	Lin, Mengshi: 1 article (09/2018)
5.	Ming, Yanlin: 1 article (09/2018)
6.	Xiao, Jianbo: 1 article (09/2018)
7.	Zheng, Yi: 1 article (09/2018)
8.	Zheng, Zhizhong: 1 article (09/2018)
9.	Choi, Hyun Sook: 1 article (04/2010)
10.	Hwang, Bang Yeon: 1 article (04/2010)

Related Diseases

1.	Weight Loss (Weight Reduction) 04/16/2010 - "GP-EX at the given doses did not produce any sign of toxicity such as weight loss, diarrhea and vomiting in rats during the 28 day treatment period and four gypenoside derivatives, gynosaponin TN-1, gynosaponin TN-2, gypenoside XLV and gypenoside LXXIV were identified from GP-EX. "
2.	Vomiting 04/16/2010 - "GP-EX at the given doses did not produce any sign of toxicity such as weight loss, diarrhea and vomiting in rats during the 28 day treatment period and four gypenoside derivatives, gynosaponin TN-1, gynosaponin TN-2, gypenoside XLV and gypenoside LXXIV were identified from GP-EX. "
3.	Hepatocellular Carcinoma (Hepatoma) 09/01/2018 - "In addition, gyp TN-1 exhibited higher inhibitory activities on SMMC7721 and Bel7402 hepatoma cells than gyp XLVI. " 09/01/2018 - "Gynosaponin TN-1 producing from the enzymatic conversion of gypenoside XLVI by naringinase and its cytotoxicity on hepatoma cell lines."
4.	Diarrhea 04/16/2010 - "GP-EX at the given doses did not produce any sign of toxicity such as weight loss, diarrhea and vomiting in rats during the 28 day treatment period and four gypenoside derivatives, gynosaponin TN-1, gynosaponin TN-2, gypenoside XLV and gypenoside LXXIV were identified from GP-EX. "

Related Drugs and Biologics

1.	gypenoside
2.	naringinase
3.	gypenoside XLVI
4.	gynosaponin TN-2