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19,20-dihydroxydocosapentaenoic acid

a docosahexaenoic acid metabolite

Also Known As:

19,20-diHDPA

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - 19,20-dihydroxydocosapentaenoic acid: 4

Experts

1.	Fleming, Ingrid: 2 articles (12/2019 - 01/2019)
2.	Armstrong, Michael: 1 article (10/2022)
3.	Barnes, Kathleen C: 1 article (10/2022)
4.	Boorgula, Meher Preethi: 1 article (10/2022)
5.	Campbell, Monica: 1 article (10/2022)
6.	Cruz, Alvaro: 1 article (10/2022)
7.	Figueiredo, Camila A: 1 article (10/2022)
8.	Johnson, Randi K: 1 article (10/2022)
9.	Manke, Jonathan: 1 article (10/2022)
10.	Mathias, Rasika A: 1 article (10/2022)

Related Diseases

1.	Diabetic Retinopathy (Retinopathy, Diabetic) 01/01/2019 - "Recent studies have identified increased sEH expression and activity and the subsequent generation of the docosahexaenoic acid-derived diol; 19,20-dihydroxydocosapentaenoic acid, as playing a major role in the development of diabetic retinopathy. "
2.	Hyperoxia 12/02/2019 - "In WT mice, hyperoxia elicited tyrosine nitration and inhibition of sEH and decreased generation of the DHA-derived diol 19,20-dihydroxydocosapentaenoic acid (19,20-DHDP). "
3.	Shock 01/01/2016 - "Six oxylipins, 17,18-DiHETE (HR = 0.83, 95% CI 0.70 to 0.99 per SD change in oxylipin level), 19,20-DiHDPA (HR = 0.79, 95% CI 0.63 to 0.98), 5,6-DiHETrE (HR = 0.73, 95% CI 0.58 to 0.91), 8,9-DiHETrE (HR = 0.76, 95% CI 0.62 to 0.95), 9,10-DiHOME (HR = 0.81, 95% CI 0.65 to 1.00), and PGF1α (HR = 1.33, 95% CI 1.04 to 1.71) were associated with the risk of appropriate ICD shock after multivariate adjustment for clinical factors. "
4.	Asthma (Bronchial Asthma) 10/01/2022 - "Asthma patients had higher scores on principal component 3 compared to controls (mean difference, 2.42; 95% confidence interval, 0.89 to 3.96), which represented lower levels of proresolving 15-HEPE, 19,20-DiHDPA, RvD5, 14-HDHA, 17-HDHA, and 13-HOTrE. "

Related Drugs and Biologics

1.	Docosahexaenoic Acids
2.	Oxylipins
3.	Tyrosine (L-Tyrosine)
4.	13-hydroxyoctadecatrienic acid
5.	15-hydroxy-5,8,11,13,17-eicosapentaenoic acid