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N-butanoylsphingosine

improves trafficking of deltaF508-cystic fibrosis transmembrane conductance regulator

Also Known As:

C4-ceramide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Caohuy, Hung: 1 article (12/2014)
2.	Eudy, Yvonne: 1 article (12/2014)
3.	Frizzell, Raymond A: 1 article (12/2014)
4.	Glover, Matthew: 1 article (12/2014)
5.	Ha, Thien-An: 1 article (12/2014)
6.	Jozwik, Catherine: 1 article (12/2014)
7.	Pollard, Harvey B: 1 article (12/2014)
8.	Xu, Andrew E: 1 article (12/2014)
9.	Yang, Qingfeng: 1 article (12/2014)

Related Diseases

1.	Pneumonia (Pneumonitis) 01/01/2023 - "In vivo mice data revealed that cold exposure compromised the airway epithelial barrier function, decreased occludin expression, and exacerbated lung inflammation, which was attenuated by the GSK2193874 or C4-ceramide injection. "
2.	Fibrosis (Cirrhosis) 12/26/2014 - "Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR)."

Related Drugs and Biologics

1.	3-Phosphoinositide-Dependent Protein Kinases
2.	Occludin
3.	Sphingolipids
4.	Protein Kinases (Protein Kinase)
5.	Glucocorticoids
6.	GSK2193874