|1.||Press, Oliver W: 13 articles (01/2015 - 05/2002)|
|2.||Lin, Yukang: 11 articles (01/2015 - 07/2005)|
|3.||Wilbur, D Scott: 11 articles (12/2011 - 05/2002)|
|4.||Pagel, John M: 10 articles (01/2015 - 04/2006)|
|5.||Hamlin, Donald K: 8 articles (02/2014 - 05/2002)|
|6.||Hnatowich, Donald J: 8 articles (07/2012 - 03/2002)|
|7.||Rusckowski, Mary: 8 articles (07/2012 - 03/2002)|
|8.||Liu, Xinrong: 7 articles (07/2012 - 04/2009)|
|9.||Gopal, Ajay K: 6 articles (01/2015 - 02/2008)|
|10.||Green, Damian J: 6 articles (01/2015 - 09/2007)|
07/21/2010 - "In conclusion, the streptavidin nanoparticle under development in this laboratory was used effectively for multimodality imaging of tumor in mice by fluorescence and nuclear detection. "
01/01/2005 - "The results also interestingly demonstrate, however, that improved clearance agents capable of removing the lower affinity streptavidin-antibody conjugate are needed to achieve comparable specificity in tumor to blood or normal organ ratios."
01/01/1998 - "Improved intratumoral penetration of radiolabeled streptavidin in intraperitoneal tumors pretargeted with biotinylated antibody."
02/01/1993 - "Tumor levels were also lower with labeled streptavidin but, because of still lower levels in liver and blood, the tumor/normal tissue ratios were improved. "
06/01/2015 - "In this study, the abilities for specific detection of CEA expressed by tumor cells with anti-CEA sdAbs biotinylated in vitro and in vivo, as well as with anti-CEA mAbs biotinylated in vitro, were compared using flow cytometry and the conjugates of streptavidin with QDs (SA-QDs). "
06/01/2011 - "To prepare streptavidin-tagged hepatitis C virus (HCV) fusion protein and explore its application for the detection of antibody against HCV infection. "
04/10/2009 - "Because our indirect immunofluorescent assay readily detected infection of both CD4(+) and CD8(+) lymphocytes, a triple labeling flow cytometric procedure was developed to quantify the individual lymphocytes infected in vivo with REV. Lymphocytes were gated with a biotinylated pan-leukocyte marker bound to streptavidin R-PE-Cy5. "
03/01/1996 - "The immune response evoked in mice after intraperitoneal infection of 30 micrograms of gal-streptavidin was decreased after PEG modification, as shown by lower antibody titres and a reduction in the number of mice that elicited an anti-gal-streptavidin response. "
05/01/1987 - "In early infection scanning electron microscopy and streptavidin immunoperoxidase staining showed marked predilection of cryptosporidia for the FAE. "
11/01/2004 - "Streptavidin accumulates at sites of inflammation and infection as a result of increased capillary permeability. "
|3.||Urinary Bladder Neoplasms (Bladder Cancer)
05/01/2010 - "[Immobilization of streptavidin-tagged bioactive hTNF-alpha on biotinylated mucosal surface of the bladder wall for treatment of superficial bladder cancer in mice]."
05/01/2010 - "To investigate a novel immunotherapy through immobilization of streptavidin-tagged hTNF-alpha on the biotinylated mucosal surface of the bladder wall for bladder cancer treatment in mice. "
01/01/2015 - "In previous study the streptavidin interleukin-2 (SA-IL-2)-modified MB49 vaccine was effective against bladder cancer in a mouse model. "
10/01/2012 - "The frozen sections of 28 non muscle invasive bladder cancer specimens were stained with CD34 antibody to label the vascular endothelium using the standard streptavidin-biotin immunoperoxidase method. "
03/01/2012 - "We developed what is to our knowledge a novel technology by which streptavidin tagged mouse GM-CSF was displayed on the surface of biotinylated bladder cancer cells to induce antitumor immunity. "
12/01/2000 - "A tetravalent single-chain antibody-streptavidin fusion protein for pretargeted lymphoma therapy."
10/15/2001 - "This study assessed the ability of a streptavidin-biotin "pretargeting" approach to improve the biodistribution of radioactivity in mice bearing Ramos lymphoma xenografts. "
01/01/2005 - "Role of biotin-binding affinity in streptavidin-based pretargeted radioimmunotherapy of lymphoma."
02/18/2003 - "Pretarget radiotherapy with an anti-CD25 antibody-streptavidin fusion protein was effective in therapy of leukemia/lymphoma xenografts."
01/01/2006 - "A phase I study of an anti-CD20/streptavidin pretargeting agent and 15 mCi/m(2)(90)Y-biotin produced objective responses with minimal toxicity among lymphoma patients, with an average tumor-to-whole-body radiation dose ratio of 49. "
|5.||Colonic Neoplasms (Colon Cancer)
11/12/2013 - "In this study, we have synthesized CdSe AQDs and compared their conjugation efficiency and imaging efficacy with commercial carboxylated OQDs in HT29 colon cancer cells using a primary antibody-biotinylated secondary antibody-streptavidin (SA) sandwich. "
12/21/2011 - "The therapeutic efficacies of radiolabeled biotin, pretargeted by monoclonal antibody (mAb)-streptavidin fusion protein CC49 scFvSA, were compared to those of radiolabeled mAb CC49, using the three radiolanthanides in an animal model of human colon cancer. "
02/01/1998 - "Nude mice bearing subcutaneous LS180 human colon cancer xenografts were intravenously administered with 200 microg of the biotinylated anti-Tn monoclonal antibody MLS128, and 2 days later they got intravenous injection of 50 microg of streptavidin. "
02/01/1998 - "The effect of the administration route and dose of streptavidin or biotin on the biodistribution of radioactivity in multistep targeting was studied in nude mice bearing intraperitoneal (IP) colon cancer xenograft. "
02/01/2000 - "Phase II trial of yttrium-90-DOTA-biotin pretargeted by NR-LU-10 antibody/streptavidin in patients with metastatic colon cancer."
|1.||Biotin (Vitamin H)
|7.||Proteins (Proteins, Gene)
|10.||Interleukin-4 (Interleukin 4)
|1.||Heterologous Transplantation (Xenotransplantation)
|4.||Neutron Capture Therapy
|5.||Quantum Dots (Quantum Dot)