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Single-Chain Antibodies

A form of antibodies consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.
Also Known As:
Fv Antibody Fragments, Single-Chain; ScFv Antibodies; Single-Chain Fv; Single-Chain Fv Antibody; Single-Chain Fv Antibody Fragments; Single-Chain Variable Fragment; Single-Chain Variable Fragment Antibodies; Single-Chain Variable Fragment Antibody; Single-Chain Variable Fragments; Antibodies, ScFv; Antibodies, Single-Chain; Antibody, Single-Chain Fv; Fragment, Single-Chain Variable; Fragments, Single-Chain Variable; Fv Antibody Fragments, Single Chain; Fv Antibody, Single-Chain; Fv, Single-Chain; Single Chain Antibodies; Single Chain Fv; Single Chain Fv Antibody; Single Chain Fv Antibody Fragments; Single Chain Variable Fragment; Single Chain Variable Fragment Antibodies; Single Chain Variable Fragment Antibody; Single Chain Variable Fragments; Variable Fragment, Single-Chain; Variable Fragments, Single-Chain
Networked: 852 relevant articles (42 outcomes, 92 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Nejatollahi, Foroogh: 10 articles (07/2020 - 03/2012)
2. Marks, James D: 8 articles (01/2012 - 01/2004)
3. Wang, Gang: 7 articles (01/2022 - 04/2002)
4. Liu, Bin: 7 articles (07/2010 - 01/2004)
5. Li, Li: 6 articles (01/2022 - 04/2002)
6. Chen, Yinting: 6 articles (02/2020 - 06/2010)
7. Huang, Kaihong: 6 articles (02/2020 - 06/2010)
8. Baeuerle, Patrick A: 6 articles (01/2018 - 04/2005)
9. Kufer, Peter: 6 articles (01/2018 - 04/2005)
10. Rosenblum, Michael G: 6 articles (01/2012 - 05/2006)

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3. Infections
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Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Monoclonal Antibodies
3. Single-Chain Antibodies
4. Antibodies
5. Immunoglobulin G (IgG)
6. Streptavidin
7. blinatumomab
8. Antigens
9. Immunotoxins (Immunotoxin)
10. Chimeric Antigen Receptors

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1. Therapeutics
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