Urinary Bladder Neoplasms (Bladder Cancer)

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10226 relevant articles (641 outcomes, 1723 trials/studies) found for this Disease

Description: Tumors or cancer of the URINARY BLADDER.

Also Known As:

Bladder Cancer; Bladder Neoplasms; Urinary Bladder Cancer; Cancer of the Bladder; Bladder Neoplasm; Bladder Tumors; Neoplasms, Bladder; Bladder Cancers; Bladder Tumor; Cancer, Bladder; Cancer, Urinary Bladder; Neoplasm, Bladder; Neoplasm, Urinary Bladder; Tumor, Bladder; Tumors, Bladder; Urinary Bladder Neoplasm; Cancer of Bladder

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Urinary Bladder Neoplasms (Bladder Cancer)
3.	Carcinoma in Situ
4.	Neoplasm Metastasis (Metastasis)
5.	Carcinoma (Carcinomatosis)

Experts

1.	Grossman, H Barton: 34 articles (11/2008 - 06/2002)
2.	Stein, John P: 26 articles (07/2008 - 06/2002)
3.	Lerner, Seth P: 20 articles (08/2008 - 03/2002)
4.	Shariat, Shahrokh F: 18 articles (09/2008 - 03/2002)
5.	Dinney, Colin P N: 18 articles (09/2008 - 04/2002)
6.	Wu, Xifeng: 14 articles (11/2008 - 02/2003)
7.	Lotan, Yair: 14 articles (10/2008 - 01/2002)
8.	Miyake, Hideaki: 14 articles (04/2008 - 11/2003)
9.	Hara, Isao: 14 articles (01/2008 - 11/2003)
10.	Kamat, Ashish M: 14 articles (01/2008 - 02/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Urinary Bladder Neoplasms:

1.	Cisplatin (Platino)FDA LinkGeneric 02/01/1984 - "We conclude that intra-arterial cisplatin can be highly effective for localized invasive bladder cancer even when relatively low doses are used. " 01/01/1990 - "This combined therapy of cisplatin and radiation is very effective for invasive bladder cancer." 03/01/1985 - "Initial intravenous cis-platinum therapy: improved management for invasive high risk bladder cancer?" 09/01/2003 - "Cis-diaminedichloroplatinum (cisplatin) has therapeutic efficacy against advanced bladder cancer. " 10/01/1992 - "These results suggest that the combined use of n-TNF and Cisplatin is promising as a clinically effective treatment against bladder cancer in human." Order ALL the reference details at left...
2.	Doxorubicin (Adriamycin)FDA LinkGeneric 01/01/1997 - "The observed high complete response and good survival rate suggest that intraarterial CDDP and doxorubicin might be highly effective for localized invasive bladder cancer." 01/01/1987 - "These preliminary results suggest that preoperative doxorubicin instillation might be effective for prolongation of the disease-free interval in patients with recurrent bladder cancer." 08/01/1996 - "This novel cytotoxic drug cured doxorubicin-refractory disease and should be investigated for the clinical management of bladder cancer." 05/01/2005 - "CONCLUSIONS: Adjuvant intravesical doxorubicin could not be shown to improve recurrence, progression and survival of superficial bladder cancer, compared with control on long-term follow-up. " 05/01/2005 - "17-year follow-up of a randomized prospective controlled trial of adjuvant intravesical doxorubicin in the treatment of superficial bladder cancer." Order ALL the reference details at left...
3.	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/01/1992 - "at the dose of 50 micrograms per animal per day during 6-week period of promotion with mitomycin C, the incidence of urinary bladder cancer was dramatically reduced. " 03/01/2004 - "Intravesical bacillus Calmette-Guérin is superior to mitomycin C in reducing tumour recurrence in high-risk superficial bladder cancer: a meta-analysis of randomized trials." 11/01/1998 - "PURPOSE: We study toxicity and efficacy of sequential intravesical therapy with mitomycin C and bacillus Calmette-Guerin (BCG) in patients with intermediate or high risk superficial bladder cancer compared to the use of intravesical mitomycin C alone. " 06/01/1989 - "A study was performed to determine the prophylactic efficacy of intravesical mitomycin C instillation in 43 patients with recurrent (more than 3), multiple (more than 3) or large (more than 3 cm.) superficial bladder tumors (stage Ta or T1). " 05/15/1984 - "Although intravesical mitomycin C (MMC) is effective in the treatment of superficial bladder cancer, its expense is a major factor limiting its use. " Order ALL the reference details at left...
4.	Epirubicin (Ellence)FDA LinkGeneric 01/01/1996 - "A prospective randomized trial on 94 eligible patients evaluated and compared the efficacy of adjuvant intravesical epirubicin and bacillus Calmette-Guérin (BCG) after complete resection of multifocal superficial bladder cancer. " 09/01/1993 - "A controlled prospective trial involving 161 patients evaluated and compared the efficacy of intravesical epirubicin and bacillus Calmette-Guérin (BCG) administration as prophylaxis against recurrences after complete transurethral resection of superficial bladder cancer. " 07/01/2008 - "CONCLUSIONS: The present study showed no statistically significant differences in terms of disease-free time and recurrence rate between high risk patients with nonmuscle invasive bladder cancer who had undergone perioperative epirubicin instillation plus delayed bacillus Calmette-Guerin and those who had undergone delayed bacillus Calmette-Guerin alone." 06/01/2000 - "CONCLUSION: Because the efficacy of combination was no better than the standard treatment and the alternating combination seemed to be related to a higher incidence of side-effects, this study albeit small, does not recommend combination therapy of BCG and epirubicin in high risk patients with superficial bladder cancer." 01/01/1998 - "OBJECTIVE: A prospective randomized study was undertaken to determine whether prophylactic maintenance instillation of epirubicin following induction treatment is beneficial in patients with superficial bladder cancer. " Order ALL the reference details at left...
5.	Methotrexate (Mexate)FDA LinkGeneric 09/01/1988 - "Our results show that methotrexate injection is highly effective in the treatment of advanced bladder cancer. " 08/01/1991 - "The experimental and clinical studies were performed to investigate the efficacy of the anal submucosal injection (ASI) of methotrexate (MTX) for bladder cancer. " 02/01/1994 - "Because methotrexate has activity in advanced bladder cancer, this trial was initiated. " 08/01/1991 - "[Experimental and clinical studies on anal submucosal injection of methotrexate for bladder cancer]" 01/01/1986 - "Phase I/II trial of intravesical methotrexate for superficial bladder tumors." Order ALL the reference details at left...
6.	gemcitabine FDA Link 08/01/2002 - "Concomitant chemo-radiation using gemcitabine as a radiosensitizer have been shown to be highly effective in pancreatic and in bladder cancer and deserve further investigation. " 09/01/2009 - "BACKGROUND: Recurrence prophylaxis with intravesical gemcitabine (GEM) was effective and safe in patients with non-muscle-invasive bladder cancer (NMIBC); efficacy as single-shot instillation remains to be proved. " 11/01/2005 - "Intravesical gemcitabine for superficial bladder cancer: rationale for a new treatment option." 10/01/2006 - "This combination enhances the efficacy of gemcitabine against bladder cancer in vivo." 06/01/2009 - "PURPOSE: A Phase I trial of twice-weekly gemcitabine and concurrent radiation therapy (RT) was performed in patients with muscle-invasive bladder cancer. " Order ALL the reference details at left...
7.	AntigensIBA 12/01/1997 - "Recent studies suggest that the bladder tumor antigen (BTA) test, an agglutination reaction for basement membrane complexes, is superior to voided urine cytology in clinical practice. " 11/01/1987 - "The bladder cancer group demonstrated 8/9 positive results for relative antigen concentrations greater than 3.0. " 11/01/2002 - "A comparison of urinary nuclear matrix protein-22 and bladder tumour antigen tests with voided urinary cytology in detecting and following bladder cancer: the prognostic value of false-positive results." 11/01/2001 - "A comparison of urinary nuclear matrix protein-22 and bladder tumour antigen tests with voided urinary cytology in detecting and following bladder cancer: the prognostic value of false-positive results." 06/01/2000 - "Studies should be initiated to determine whether viral antigen expression is involved in the immune rejection of MBT-2 bladder cancer. " Order ALL the reference details at left...
8.	nuclear matrix protein 22IBA 04/01/2000 - "The purpose of this study was to evaluate, from the perspective of the Quebec health system, the cost and cost-efficacy of using NMP22 compared with the currently recommended monitoring procedure following a transurethral resection of a bladder tumor (TURBT). " 12/01/2008 - "CONCLUSION: Combining NMP22 with malignant or suspicious cytological result improved sensitivity for the detection of bladder cancer but with a major decrease in specificity, suggesting a potential role in screening rather than diagnosis." 03/01/2006 - "CONCLUSION: The NMP22 BladderChek test is an in vitro qualitative test that is easily available and cheap; it can be performed by a urologist in the office and results can be interpreted within 30 min. The NMP22 test is superior to cytology for all grades and stages in the detection of recurrence in patients with a history of superficial bladder cancer. " 12/01/2005 - "OBJECTIVE: To study the diagnostic efficacy of the NMP22 BladderChek test and to compare it to cytology in the detection of bladder cancer. " 03/01/2009 - "OBJECTIVES: To assess the efficacy of nuclear matrix protein 22 (NMP-22) in the diagnosis of recurrent, superficial bladder cancer and whether it can predict for future recurrence. " Order ALL the reference details at left...
9.	Vinblastine (Vinblastine Sulfate)FDA Link 04/01/2005 - "Phase II study of radiochemotherapy with vinblastine in invasive bladder cancer." 12/15/1992 - "Concurrent vinblastine and radiation therapy in bladder cancer." 04/01/1985 - "Vinblastine and methotrexate for advanced bladder cancer." 08/01/2003 - "MATERIAL AND METHODS: Fifty-one patients with invasive bladder tumor (T2) were treated using transurethral resection (TUR) followed by three cycles of systemic chemotherapy (carboplatin-vinblastine). " 12/01/1994 - "Pre-chemotherapy bladder tumor tissue was retrospectively analyzed in 21 patients treated with neoadjuvant cisplatin, methrotrexate and vinblastine. " Order ALL the reference details at left...
10.	Fluorouracil (Carac)FDA LinkGeneric 12/01/1993 - "[Efficacy of 48-hour infusion of 5-fluorouracil for gall bladder cancer]" 11/01/1991 - "It is concluded that, in this preclinical in vivo model of human bladder cancer, 1) CDDP and 5FU show substantial enhanced efficacy when combined, and 2) DP serves as an in vivo chemosensitizer of both CDDP and 5FU; DP further augments the efficacy of this binary combination. " 09/01/1999 - "The current study demonstrates that combination treatment of bladder cancer cells with CDDP, 5-FU and anti-Fas mAb overcomes their resistance. " 04/01/1989 - "[Phase II study of 5-FU tablet in bladder tumor]" 11/01/1988 - "[Phase II study of 5-FU tablet in bladder tumor]" Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 08/01/1984 - "Intravesical chemotherapy is one of the most effective treatments for superficial bladder tumors. " 11/01/2003 - "While it is now clear that chemotherapy can contribute to improved outcome for some patients with muscle invasive bladder cancer, selection criteria for this very heterogeneous disease are lacking. " 08/01/1994 - "The results suggest that intra-arterial chemotherapy plus radiotherapy is a useful regimen for patients with locally advanced bladder cancer, and bladder function may be preserved in those who achieve a complete remission." 01/01/1994 - "Regional chemotherapy in the presence of reduced arterial blood stream in the system of internal iliac arteries is the optimal hemostasis method for inoperable patients with locally disseminated bladder cancer: it helped attain a stable prolonged hemostasis in 100% of patients." 01/01/1992 - "In conclusion, TPA has been proven as a valuable and a reliable marker for monitoring therapeutic efficacy of chemotherapy for advanced bladder cancer." Order ALL the reference details at left...
2.	Cystectomy 11/01/2007 - "The best treatment for high-grade T1 bladder cancer is cystectomy." 03/01/2004 - "Radical cystectomy remains the best option for invasive bladder cancer, however, there are few reports about the best approach to such individuals. " 12/01/1998 - "Until now, radical cystectomy has been considered the most effective treatment for invasive bladder cancer. " 04/01/1998 - "Until now, radical cystectomy has been considered the most effective treatment for invasive bladder cancer. " 02/01/1990 - "For invasive bladder cancer (invasive of bladder muscle or beyond) improved techniques of cystectomy and radiotherapy have reduced the complications of treatment and may have contributed small but important improvements in cure. " Order ALL the reference details at left...
3.	Intravesical Administration 10/01/2008 - "CONCLUSIONS: Intravesical instillation of BCG is the most effective in the long term when chosen as the initial prophylactic therapy for the prevention of recurrence in superficial bladder cancer." 07/01/2006 - "Intravesical instillation of Bacillus Calmette-Guérin (BCG) after transurethral resection is the most effective treatment for superficial bladder cancers. " 06/01/2003 - "CONCLUSIONS: The data suggest that intravesical instillation of BCG is more effective when no prior treatment has been attempted, and that best results may be achieved if BCG is chosen as the initial therapy for superficial bladder cancer. " 12/01/1990 - "Intravesical administration of bacillus Calmette-Guerin has been shown to be highly effective treatment of superficial bladder cancer. " 10/01/1986 - "Intravesical instillation of bacille Calmette Guerin (BCG) currently is considered the most effective treatment for recurrent superficial bladder cancer, but little is known about the mechanism of action. " Order ALL the reference details at left...
4.	Immunotherapy 03/01/2001 - "Our previous animal studies demonstrated that aged garlic extract was highly effective, and unlike the approved immunotherapy for human bladder cancer, bacillus Calmette--Guérin (BCG), garlic was effective when added to the diet. " 01/01/1990 - "As bacillus Calmette-Guérin (BCG) immunotherapy is highly effective for most but not all superficial bladder tumors, there is a need to define predictors of response to this mode of treatment. " 04/01/2001 - "The use of BCG immunotherapy, a very major advance in the management of superficial bladder cancer, is limited by the frequency of adverse events. " 02/01/2002 - "OBJECTIVES: Immunotherapy with bacille Calmette-Guérin (BCG) has been proposed in the past decade as first-line treatment for high-grade superficial bladder cancer (G3T1). " 05/01/2001 - "Bacille Calmette-Guérin immunotherapy has documented efficacy in the management of high-risk superficial bladder cancer. " Order ALL the reference details at left...
5.	Lymph Node Excision (Lymph Node Dissection) 04/01/2002 - "CONCLUSION: The more extensive lymphadenectomy significantly improved the prognosis of patients with invasive bladder cancer and therefore, represents a potentially curative procedure. " 07/15/2005 - "Studies also indicate that more extensive lymphadenectomy significantly improved the prognosis of patients with bladder cancer, not only by providing prognostic information but perhaps it is also due to its inherent therapeutic value. " 07/01/2008 - "Although the absolute limits of lymphadectomy at the time of surgery have not been precisely defined, there is a growing body of evidence to suggest that an extended lymph node dissection may be beneficial for staging and survival in both node-negative and -positive bladder cancer patients. " 09/01/1990 - "A comparative study performed in 84 patients revealed a sensitivity rate of 36.3%, a specificity of 87.2%, and an accuracy rate of 66.2% for CAT scanning and, although radiologic evaluation afforded good results, pelvic lymphadenectomy continues to be the method of choice for correct staging of infiltrating bladder tumors." 02/01/2008 - "Re: Honma I, Masumori N, Sato E, et al: Removal of more lymph nodes may provide better outcome, as well as more accurate pathologic findings, in patients with bladder cancer-analysis of role of pelvic lymph node dissection. " Order ALL the reference details at left...

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