Peroxidase (Myeloperoxidase)

Subscribe to Selected New Research on Peroxidase

6495 relevant articles (135 outcomes, 509 trials/studies) found for this Bio-Agent

Description: A hemeprotein from leukocytes. Deficiency of this enzyme leads to a hereditary disorder coupled with disseminated moniliasis. It catalyzes the conversion of a donor and peroxide to an oxidized donor and water. EC 1.11.1.7.

Also Known As:

Myeloperoxidase; Hemi-Myeloperoxidase; Hemi Myeloperoxidase; Donor:hydrogen-peroxide oxidoreductase

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1

Enzymes: 25587

Oxidoreductases: 7118

Peroxidases: 138

Peroxidase: 6495

guaiacol peroxidase: 6

peroxidasin: 1

Petunia hybrida PeTh3 protein

Experts

1.	Hazen, Stanley L: 16 articles (09/2008 - 11/2002)
2.	Brennan, Marie-Luise: 10 articles (09/2008 - 11/2002)
3.	Heinecke, Jay W: 8 articles (11/2007 - 08/2003)
4.	Suzuki, K: 7 articles (06/2007 - 04/2000)
5.	Heeringa, Peter: 5 articles (12/2007 - 10/2002)
6.	Gao, Ying: 5 articles (04/2007 - 10/2004)
7.	Zhang, Ying: 5 articles (01/2007 - 10/2004)
8.	Maslov, A K: 5 articles (11/2001 - 03/2000)
9.	Eiserich, Jason P: 4 articles (08/2008 - 09/2003)
10.	Baldus, Stephan: 4 articles (08/2008 - 09/2003)

Related Diseases

1.	Colitis 01/01/2007 - "Both probiotics showed intestinal anti-inflammatory effects in this model of experimental colitis, as evidenced histologically and by a significant reduction of colonic myeloperoxidase activity (P<0.05). " 02/01/2006 - "Histologic scores of colonic damage and myeloperoxidase activity were lower in both probiotic-treated groups compared with those of the colitis control group (P<0.001), although the mentioned scores improved significantly more in the high-EPS group than in the low-EPS group (P<0.001). " 09/01/2008 - "Leukocyte recruitment, assessed by intravital microscopy, and inflammatory parameters (myeloperoxidase (MPO), macroscopic and microscopic damage) were assessed during the development of colitis. " 09/01/2008 - "Myeloperoxidase (MPO) and bacterial translocation to the liver and to the mesenteric lymph nodes (MLN) decreased significantly in all groups compared to colitis control. " 02/01/2008 - "The rats were decapitated 8 days after the induction of colitis, and the colonic tissue wet weight, macroscopic and microscopic lesion score, and tissue myeloperoxidase (MPO) activity were determined. " Order ALL the reference details at left...
2.	Edema 09/01/2009 - "INO-2002 (30 and 100 mg kg(-1)) reduced the LPS-mediated infiltration of leukocytes and edema as evidenced by bronchoalveolar lavage fluid reduction in levels of myeloperoxidase and protein. " 09/01/2009 - "After 24 h, bronchoalveolar lavage fluid was obtained to measure leukocyte infiltration by myeloperoxidase levels, lung edema by protein levels, and proinflammatory chemokine (macrophage inflammatory protein 1alpha) and cytokine (TNF-alpha, IL-1, and IL-6) levels. " 06/01/2009 - "LPS also caused 1) reduced transthoracic static compliance, 2) lung edema, 3) neutrophilic infiltration, and 4) increased neutrophil myeloperoxidase activity in pla2g5(+/+) mice. " 05/04/2009 - "RESULTS: CIE inhibited topical edema in the mouse ear, following administration at 200mg/kg (i.p.), leading to substantial reductions in skin thickness and tissue weight, inflammatory cytokine production, neutrophil-mediated myeloperoxidase activity, and various histopathological indicators. " 01/12/2009 - "RESULTS: ACE inhibited topical edema in the mouse ear, following administration at 200mg/kg (i.p.), leading to substantial reductions in skin thickness and tissue weight, inflammatory cytokine production, neutrophil-mediated myeloperoxidase (MPO) activity, and various histopathological indicators. " Order ALL the reference details at left...
3.	Inflammation 03/01/2008 - "PURPOSE: The aim of this study was to analyze the potential impact of inflammation and loading on PISF myeloperoxidase (MPO) levels, in comparison with GCF. " 06/01/2007 - "Histological study and colonic inflammation were assessed by gross appearance and myeloperoxidase (MPO) activity. " 10/01/2005 - "Moreover, the results of the study confirm the need for a change of the threshold value of peroxidase-positive cells according to WHO definition to lower levels for definition of silent genital tract inflammation." 11/15/2001 - "Studies in embryos after tail transection demonstrated that mpx- and peroxidase-expressing cells were mobile and localized to a site of inflammation, indicating functional capability of these embryonic granulocytes. " 05/01/2001 - "Myeloperoxidase (MPO) activity was determined, and a histopathological study was carried out in paw tissue 4 h after induction of inflammation. " Order ALL the reference details at left...
4.	Lung Injury 04/01/2009 - "It was noted that in severe lung injury, myeloperoxidase activity in the blood increased significantly, but still reflected the processes taking place in the lung parenchyma. " 10/01/2008 - "There was a corresponding reduction in lung injury, as demonstrated by reduced myeloperoxidase content and reduced wet-to-dry ratio. " 09/01/2008 - "Pancreatic and pulmonary injury was assessed by histology, wet-to-dry weight ratio, and myeloperoxidase activity. " 08/01/2008 - "Lung injury was assessed histologically and by the magnitude of neutrophil sequestration as reflected in myeloperoxidase levels. " 01/01/2008 - "Lung oedema, myeloperoxidase and histological lung injury score were higher in the HVCMV group, but not different among all others. " Order ALL the reference details at left...
5.	Body Weight (Weight, Body) 08/01/2006 - "RESULTS: Both Cur and Dex improved body weight loss, ameliorated histological images and decreased macroscopic score and myeloperoxidase activity. " 09/01/2007 - "Daily treatment with 2.5% DSS for 6 days caused damage to the colon, with a decrease in body weight gain and colon length as well as an increase of myeloperoxidase (MPO) activity. " 06/01/2007 - "The serum level of UA was determined with unicase-peroxidase conjugate method, the blood levels of K+, Na+, Cl-, Ca2+ were determined by automatic biochemical analysor, and changes of body weight were measured before and after dialysis. " 04/01/2004 - "A minimum DSS load > or = 30 mg/g body weight over 7 days resulted in a significantly elevated colonic myeloperoxidase (MPO) activity, compared to mice receiving less DSS and controls (P < 0.05). " 12/01/2001 - "Colonic damage score, ratio of distal colon wet weight to body weight, and myeloperoxidase activity were evaluated as measures of the therapeutic effect of PD, whereas the ratio of thymus wet weight to body weight was evaluated as a measure of the side effect of PD. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antineutrophil Cytoplasmic Antibodies (ANCA)
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Lactoferrin
4.	Catalase
5.	Interleukin-10 (Interleukin 10)
6.	Peroxidase (Myeloperoxidase)
7.	Antibodies
8.	Antigens
9.	Glutathione (Reduced Glutathione)
10.	Myeloblastin (Proteinase 3)

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Aftercare (After-Treatment)
3.	Drug Therapy (Chemotherapy)
4.	Oral Administration
5.	Renal Dialysis (Hemodialysis)

Best Treatments:
Research Summary Report
on Colitis

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 575 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>