|1.||Shin, Eak Kyun: 14 articles (03/2009 - 09/2002)|
|2.||Koh, Kwang Kon: 14 articles (03/2009 - 09/2002)|
|3.||Ahn, Jeong Yeal: 13 articles (03/2009 - 09/2002)|
|4.||Brzozowski, Tomasz: 12 articles (01/2015 - 04/2002)|
|5.||Han, Seung Hwan: 12 articles (03/2009 - 09/2003)|
|6.||Cracowski, Jean-Luc: 11 articles (07/2015 - 01/2005)|
|7.||Higashi, Yukihito: 11 articles (01/2015 - 05/2002)|
|8.||Konturek, Stanislaw J: 11 articles (01/2014 - 04/2002)|
|9.||Piek, Jan J: 11 articles (10/2013 - 07/2002)|
|10.||Abelson, Mark B: 11 articles (08/2011 - 03/2002)|
06/01/2009 - "The results of this study suggest that an IC adenosine continuous infusion method via a microcatheter is safe and effective in inducing steady-state hyperemia and more potent and quicker in inducing optimal hyperemia than the standard IV infusion method."
08/01/2005 - "IC infusion of adenosine seems to be a safe and effective method of inducing maximal hyperemia for FFR measurement."
11/15/2015 - "Use of the hybrid iFR-FFR strategy, assessing lesions in an iFR-gray zone of 0.86-0.93 by FFR, improved classification accuracy to 94.7%, and diagnosis would have been established in 61% of patients without adenosine-induced hyperemia. "
08/01/2005 - "Various methods are used to induce maximal hyperemia for physiologic studies, but the feasibility and efficacy of continuous intracoronary (IC) infusion of adenosine for measurement of fractional flow reserve (FFR) has not been well-defined. "
06/01/2009 - "We evaluated the efficacy of the intracoronary (IC) continuous adenosine infusion method via a microcatheter for inducing maximal coronary hyperemia. "
12/01/2013 - "Acute hyperoxic breathing improved resting tissue O(2) saturation (an expression of higher oxygen delivery) and decreased the oxygen consumption rate and reactive hyperemia time during reperfusion, possibly due to increased oxidative stress and evoked vasoconstriction."
05/01/1975 - "As far as therapy is concerned in the prevention of vascular colaps and the improvement of the oxemia, oxygen is very useful when there is a venous congestion (clinically, X rays, and oxemia). "
11/01/1990 - "To determine whether extremity vasodilatory capacity may be augmented in older persons by endurance exercise training, lower leg blood flow and conductance were characterized plethysmographically at rest and during maximal hyperemia in 9 men and 10 women aged 64 +/- 3 (SD) yr before and after 31 +/- 6 wk of walking and jogging at 70-90% of maximal oxygen uptake for 45 min 3-5 days/wk. Maximal oxygen uptake expressed as milliliters per kilogram per minute improved 25% in men and 21% in women (P less than 0.01). "
02/01/2014 - "This study evaluated the approach of a cavoaortic shunt included in the LVAD circuit, which would aim to relieve venous congestion and improve hemodynamics with preserved oxygen delivery during induced right ventricular failure. "
02/09/2010 - "The aim of this study was to evaluate vascular function in the lower extremities by making direct time-course measurement of oxygen saturation in the femoral/popliteal arteries and veins during cuff-induced reactive hyperemia with magnetic resonance imaging-based oximetry. "
06/01/2005 - "All 3 treatment arms significantly improved flow-mediated dilator response to hyperemia and reduced plasma levels of malondialdehyde relative to baseline measurements. "
01/01/2015 - "Blood flow, reactive hyperemia, plasma nitrite, and malondialdehyde were measured before and 40 min after the interventions in both sessions. "
01/01/2015 - "The aim of this study was to analyse the effects of a single session of resistance exercise on blood flow, reactive hyperemia, plasma nitrite, and plasma malondialdehyde in patients with peripheral artery disease. "
03/20/2009 - "Amlodipine therapy significantly improved flow-mediated dilator response to hyperemia and reduced plasma malondialdehyde levels to a greater extent than placebo (P<0.001 and P=0.035). "
12/14/2004 - "All 3 treatment arms significantly improved flow-mediated dilator response to hyperemia and decreased plasma malondialdehyde and monocyte chemoattractant protein-1 levels relative to baseline measurements. "
|4.||bimatoprost (Lumigan)FDA Link
04/01/2014 - "All functional parameters and conjunctival hyperemia improved in the bimatoprost 0.01% group at each follow-up visit (P < 0.05) and in comparison with bimatoprost 0.03% (P < 0.05). "
04/01/2010 - "Bimatoprost 0.01% was equivalent to bimatoprost 0.03% in lowering IOP throughout 12 months of treatment and demonstrated improved tolerability, including less frequent and severe conjunctival hyperemia. "
01/01/2012 - "This real-world, observational study found that bimatoprost 0.01% instilled once daily reduced IOP by a mean of 30% from baseline without moderate or severe ocular hyperemia in 93% of treatment-naïve subjects with POAG or OHT."
01/01/2010 - "Bimatoprost 0.01% was noninferior to vehicle with respect to conjunctival hyperemia in this study population. "
01/01/2005 - "These studies suggest that conjunctival hyperemia, a side effect of bimatoprost treatment, results from non-inflammatory, pharmacologically based vasodilatation."
|5.||Indomethacin (Indometacin)FDA LinkGeneric
03/01/1986 - "In 10 experiments, pretreatment with 50 mg indomethacin i.v. resulted in a significant reduction of the hyperemia reaction. "
07/01/1993 - "Indomethacin was also found to be effective in suppressing reactive hyperemia. "
01/01/2006 - "The intragastric administration of indomethacin induced hyperemia and hemorrhagic erosions in the rat stomachs. "
05/01/2000 - "Our results provide evidence that systemic application of Indomethacin leads to vasodilatation of the main arteriole of the villus in the rat ileum and hyperemia in the mucosa. "
08/01/1995 - "The effect of indomethacin was evaluated from the extent of cutaneous hyperemia. "
01/23/1989 - "Since regional blood flow could affect the clearance of plasma lipoproteins, measurements were taken of forearm blood flow, forearm vascular resistance, and maximal forearm vasodilatory potential during reactive hyperemia. "
04/01/1980 - "These findings suggest the importance of employing physiological perfusion pressures in studies designed to examine hepatic lipoprotein metabolism and also suggest a possible mechanism in the pathogenesis of fatty change seen in the "nutmeg" liver of chronic venous congestion."
09/15/2003 - "Compared with baseline, the step I diet significantly changed lipoprotein levels, significantly improved the percent flow-mediated dilation response to hyperemia by 32 +/- 7% (p <0.001), increased plasma levels of nitrate by 45 +/- 12% (p = 0.013), and lowered plasma levels of malondialdehyde by 7 +/- 4% (p = 0.011). "
01/01/2012 - "Here, we investigated the potential associations between lipoprotein subclass cholesterol concentrations and endothelial dysfunction evaluated by digital reactive hyperemia peripheral arterial tonometry (PAT). "
10/01/2004 - "The purpose of this study was to clarify whether coronary flow velocity reserve (CFVR), evaluated by adenosine 5'-triphosphate-induced hyperemia, is improved by single low-density lipoprotein (LDL) apheresis. "
|7.||latanoprost (Xalatan)FDA Link
01/01/2014 - "It is as effective as conventional latanoprost, has a lower incidence of hyperemia, and can be stored at room temperature. "
01/01/2011 - "To study any correlation between a short-term change in conjunctival hyperemia severity and the intraocular pressure-lowering effect induced by latanoprost. "
09/01/1993 - "These side effects became less pronounced during the study, and at the end there was little difference in the degree of conjunctival hyperemia between placebo- and drug-treated eyes, and no drug-related ocular irritation was reported with the two lowest concentrations of PhXA41. "
11/01/1991 - "In a second study we determined the effect of 10 micrograms of PhXA34 once daily for 7 days on intraocular pressure, outflow facility, aqueous flow, blood-aqueous barrier permeability, ocular discomfort, and hyperemia. "
02/01/2015 - "The major safety finding was ocular hyperemia, which was more common for both concentrations of AR-13324 than for latanoprost."
|8.||Fibrinogen (Factor I)FDA Link
03/01/1985 - "Fibrinogen reduction in a slight increase in baseline CBF and the elimination of post-ischemic hyperemia at 24 hours. "
06/01/2005 - "Fenofibrate significantly improved percent flow-mediated dilator response to hyperemia by 48 +/- 5% (P < 0.001) and lowered plasma levels of high-sensitivity C-reactive protein (hsCRP) relative to baseline measurements from 0.80 to 0.70 mg/l (P = 0.001) and fibrinogen levels by 16 +/- 3% (P < 0.001). "
06/01/2004 - "Compared with diet alone, simvastatin significantly improved the percent flow-mediated dilator response to hyperemia and lowered plasma levels of tumor necrosis factor (TNF)-alpha, intercellular adhesion molecule type-1 (ICAM-1), serum levels of CRP, and fibrinogen (P<0.001, P<0.001, P=0.035, P<0.001 and P=0.014, respectively). "
01/01/2005 - "Plasma viscosity was assessed on a Coulter viscometer, fibrinogen by Clauss, vWf, D-dimer and soluble P selectin by ELISA, and FMD by reactive hyperemia. "
01/01/1990 - "Among those 13 characteristics detected as optimal amount there were thrombin time, thrombin coagulase time as parameter of haemostasis both before and after venous congestion, reptilase time prior to venous congestion and fibrinogen concentration after it. "
|9.||Simvastatin (Zocor)FDA LinkGeneric
06/01/2013 - "Post-injury treatment of Aβ transgenic mice with simvastatin lowered brain Aβ concentrations, attenuated deficits in CBF ipsilateral to injury, restored hyperemia contralateral to injury, and reduced brain tissue loss. "
01/01/2012 - "Although the 20 mg/kg dose of simvastatin inhibited mononuclear leukocyte infiltration, the 40 mg/kg dose induced hyperemia. "
10/01/1996 - "For 18 of the same patients (11 taking simvastatin, 7 receiving placebo), forearm strain-gouge plethysmography was performed at baseline and after 4 weeks, both at rest and during reactive hyperemia. "
11/01/2004 - "Simvastatin and fenofibrate significantly improved the percent flow-mediated dilator response to hyperemia by 183+/-41% and by 30+/-7%, respectively (each P<0.001); however, simvastatin significantly improved more (P<0.001). "
08/01/2004 - "Ramipril alone or simvastatin combined with ramipril significantly improved the percent flow-mediated dilator response to hyperemia (both P<0.001), however, simvastatin combined with ramipril showed significantly more improvement than ramipril alone (P<0.001 by ANOVA). "
|10.||Nitroglycerin (Dynamite)FDA LinkGeneric
07/01/2005 - "Changes in vasodilator response to reactive hyperemia were significantly improved (p<0.01), while the response to nitroglycerin was not changed, suggesting the improvement of endothelial function. "
09/01/2007 - "Vascular reactivity was assessed at each phase of the study using high-frequency brachial artery ultrasound in response to flow-mediated hyperemia, cold pressor testing, and sublingual nitroglycerin. "
01/01/2005 - "Clinical indices, exercise tolerance, endothelial function (the study of brachial artery in reactive hyperemia and sublingual intake of nitroglycerin) were studied in 30 patients with stable angina FC II-III before the treatment, 1 and 3 months after the treatment. "
01/01/2004 - "Reactive hyperemia and nitroglycerin tests were performed to study endothelial function. "
05/01/2002 - "To investigate the effects of non-ECG-triggered imaging during ultrasound studies of endothelial function, brachial artery diameters were measured throughout the cardiac cycle at rest, during reactive hyperemia, and after administration of nitroglycerin. "
10/01/2012 - "All items evaluated improved after treatment, but only conjunctival hyperemia and TMH improved significantly. "
01/01/2014 - "Bulbar conjunctival hyperemia, ocular surface temperature, and ocular symptoms repeated before and every 10 minutes after treatment for 1 hour. "
07/01/2012 - "Conjunctiva hyperemia and superficial punctate keratopathy after treatment with each fixed combination therapy were assessed and compared with the baseline. "
06/01/2008 - "Eighty-six percent of the patients with residual hyperemia on sonographic examination after treatment had an unfavorable clinical course compared with only 30% of the patients with no, or barely visible, residual hyperemia (p < 0.01). "
04/01/2003 - "The flow-mediated vasodilator function was determined before and 12 months after treatment by measuring the change in brachial artery diameter during increases in flow induced by reactive hyperemia. "
01/01/1985 - "In response to venous congestion, capillary flow rate falls drastically, whereas Laser-Doppler flow is much less dramatically reduced. "
09/01/2000 - "Laser Doppler flowmetry (LDF) is a noninvasive method to monitor skin perfusion and is very useful in studying reactive hyperemia signals. "
09/10/2008 - "In this study we used mechanical stimulation to induce oligemia and hyperemia, in surgically prepared cats and rats, using laser Doppler probes to measure the cerebral blood flow and single cell cortical recording to measure the spike/neuronal burst, both generated as a consequence of CSD. "
01/01/2008 - "In this study, we aimed to characterize the "effective" occlusion duration needed to elicit sufficient postocclusive hyperemia (PORH) responses in forearm skin using laser Doppler fluximetry (LDF), in subjects with differing age, gender and menstrual phases. "
09/01/2005 - "In this study, we investigated the reproducibility of several different laser-Doppler-derived parameters in the measurement of postocclusive reactive hyperemia at forearm skin in healthy subjects. "
03/01/2007 - "In addition to allowing the patency of the middle hepatic vein tributaries and interposition vein graft to be assessed during the early postoperative period, Doppler sonography can depict the flow direction in the portal vein and in the middle hepatic vein tributaries; therefore, Doppler sonography can reveal reversal of portal flow direction in patients with acute and severe venous congestion and can show the presence of a functional intrahepatic anastomosis between the hepatic vein tributaries during the follow-up period in those with improved congestion."
10/01/2007 - "Angiography and pressure measurement at the proximal and distal portions of the left internal thoracic artery graft during maximal hyperemia with a pressure guide wire were performed at 1 month (early study) and 6 months (late study) after surgical intervention. "
11/01/2006 - "According to the results of this study, minimal modifications of the transection line can provide significant increases in functional volumetric parameters by avoiding venous congestion in the marginal zone of the graft, drained by the middle hepatic vein."
05/21/2015 - "Risk of venous congestion in live donors of extended right liver graft."
03/01/2015 - "Medicinal leeches (Hirudo medicinalis) are indicated for salvage of tissue flaps, grafts, or replants when venous congestion threatens tissue viability. "
01/01/1984 - "We measured velocity of blood flow and pial artery diameter to characterize the time course of reactive hyperemia and used microspheres to study regional blood flow in the brain. "
12/19/1977 - "[Study of the coronary arteriole bed at rest and during hyperemia by selective coronary scintigraphy with labeled microspheres]."
10/31/2006 - "During hyperemia alone, LCx probe and microsphere flows and MCE-derived red cell velocity increased from baseline (30+/-14 versus 125+/-62 mL/min, P<0.0005; 1.5+/-0.5 versus 6.6+/-2.0 mL x min(-1) x g(-1), P<0.0005; and 0.53+/-0.14 versus 0.96+/-0.45 second(-1), P=0.030, respectively); intramyocardial blood volume was unchanged. "
11/01/2004 - "The pro-arteriogenic effect of MCP-1 was confirmed by flow measurements during reactive hyperemia, as demonstrated by increased flow ratio (PBS 0.56+/-0.07 vs. MCP-1 0.77+/-0.06, no unit, p<0.0001), ankle-brachial index and microsphere-based conductance measurements (PBS 50.8+/-2.1 vs. MCP-1 225.8+/-8.8 ml/min/100 mm Hg, p<0.001). "
11/01/2002 - "At 5, 15 and 30 weeks of age, ten rats in each group were subjected to systemic and coronary hemodynamic measurements using the colored microsphere technique before and during maximal coronary hyperemia and histological assessment with Azan-Mallory stain of the coronary arterioles. "
05/01/2014 - "Some studies recommended leech therapy for this kind of injury after vascular repair to decrease venous congestion. "
03/01/2012 - "Although there are numerous case reports and small case series describing the experiences of leech therapy in various circumstances, there are relatively few large studies evaluating the effectiveness of leeching to relieve venous congestion. "
05/01/1999 - "This study compares the effectiveness of alleviating venous congestion with mechanically-made outlets or leech therapy in promoting skin flap survival. "
03/01/2015 - "Successful salvage of venous congestion was done using medicinal leech therapy, once daily, for 5 days. "
10/01/2014 - "When venous congestion cannot be corrected, total flap removal may be a better option than attempted salvage with leech therapy."