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C-Reactive Protein

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A plasma protein that circulates in increased amounts during inflammation and after tissue damage.

Also Known As:

C Reactive Protein; Protein, C-Reactive; Proteins, specific or class, C-reactive

Networked: 11048 relevant articles (243 outcomes, 1325 trials/studies) for this Bio-Agent, Comments

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Bio-Agent Context: Research Results

Experts

1.	Ridker, Paul M: 79 articles (03/2010 - 01/2002)
2.	Rifai, Nader: 55 articles (02/2009 - 01/2002)
3.	Tracy, Russell P: 41 articles (07/2009 - 02/2002)
4.	Koenig, Wolfgang: 31 articles (12/2009 - 07/2002)
5.	Stenvinkel, Peter: 30 articles (11/2009 - 11/2002)
6.	Cushman, Mary: 29 articles (02/2010 - 12/2002)
7.	Jialal, Ishwarlal: 29 articles (12/2009 - 02/2002)
8.	Zoccali, Carmine: 27 articles (01/2009 - 01/2002)
9.	Rumley, Ann: 26 articles (03/2010 - 07/2003)
10.	Lindholm, Bengt: 26 articles (11/2009 - 01/2002)

Related Diseases

1.	Inflammation 12/01/2009 - "The inclusion of the C-reactive protein (CRP) inflammation marker into the model highly improved the power of death prediction. " 05/01/1997 - "The level of C-reactive protein (CRP), currently the best quantitative parameter of inflammation, was used as the gold standard. " 09/01/2004 - "RESULTS: Significant improvement was found in the BASFI (median baseline 5.88, 3 months 3.63, p = 0.021), BASDAI (median baseline 5.63, 3 months 3.48, p = 0.028), ASQoL (median baseline 12, 3 months 8, p = 0.011) and laboratory measures reflecting inflammation, with C reactive protein (median baseline 31 mg/l, 3 months 17 mg/l, p = 0.036) and erythrocyte sedimentation rate (median baseline 19 mm/1st h, 3 months 15 mm/1st h, p = 0.008) also showing significant improvement. " 05/01/1991 - "Of the serologic parameters of inflammation, only the C-reactive protein level improved in the patients with a favorable response. " 03/01/2008 - "These improvements are coupled with a mild to moderate improvement in plasma markers of inflammation, such as C-reactive protein and erythrocyte sedimentation rate. " Order ALL the reference details at left...
2.	Infection 05/01/2009 - "Repeated measurements over the clinical course of AAV revealed an increase during remission to 1,180 +/- 130 U (n = 11), while there was a significant rapid decrease to 369 +/- 441 U (P < 0.01) concomitantly with elevation in plasma C-reactive protein and BG levels in patients with AAV that had AsP or PCP infection. " 01/01/2006 - "PCT is superior to C-reactive protein in discriminating infections in this setting. " 12/01/2001 - "C-reactive protein as an indicator of infection, may help to detect surgical complications early and provide a better outcome for patients. " 10/01/2000 - "Human C-reactive protein is protective against fatal Salmonella enterica serovar typhimurium infection in transgenic mice." 01/01/1995 - "Recognition of the changing pattern of C-reactive protein was very useful in excluding infection and minimizing unnecessary antibiotic therapy in managing neonatal infection." Order ALL the reference details at left...
3.	Pain (Aches) 06/01/2001 - "Both groups experienced a significant improvement in erythrocyte sedimentation rate, C reactive protein, Ritchie Articular Index, and pain score by 24 weeks (p<0.001, Friedman test). " 06/01/2000 - "RESULTS: All 10 corticosteroid treated patients responded to the first injection with a significant reduction in duration of morning stiffness, VAS pain scale, patient and physician global assessment, erythrocyte sedimentation rate, and C-reactive protein. " 10/12/1991 - "After four weeks at the health farm the diet group showed a significant improvement in number of tender joints, Ritchie's articular index, number of swollen joints, pain score, duration of morning stiffness, grip strength, erythrocyte sedimentation rate, C-reactive protein, white blood cell count, and a health assessment questionnaire score. " 03/01/1991 - "All patients improved during treatment clinically (Ritchie's index, morning stiffness, pain scale) (p = 0.005), as well as biologically C-reactive protein (p = 0.008) with an average 60% reduction of each of these variables at Day 15, and clinical benefit lasted over 6 months in some patients. " 01/01/1995 - "The efficacy of SST14 was evaluated by determining acute phase parameters (erythrocyte sedimentation rate, C-reactive protein [CRP]) and by clinical assessment (pain at rest and on movement, joint tenderness, morning stiffness, spontaneous pain). " Order ALL the reference details at left...
4.	Crohn Disease (Crohn's Disease) 12/01/2003 - "CDP571 is not effective in unselected patients with active Crohn's disease, but it may be effective in patients with elevated C-reactive protein. " 04/01/2009 - "CD remission was defined as a Crohn s Disease Activity Index (CDAI) < 150 points together with C-reactive protein < 5 mg/L. " 07/01/1995 - "It seems that the currently existing clinical signs used for Crohn's disease activity would be quantitatively improved by adding some easily made laboratory tests such as C-reactive protein." 08/01/1982 - "C-reactive protein levels corresponded closely with clinical and pathological indices of relapse, remission and response to therapy in patients with Crohn's disease. " 11/01/2007 - "A statistically significant association between the Crohn's disease activity index score and the C-reactive protein level was found in our study (r=0.302; p=0.001). " Order ALL the reference details at left...
5.	Fever (Fevers) 10/01/2003 - "The study group, when compared with a control group, had a significant reduction in the incidence and duration of fevers (P < 0.05) and maximum C-reactive protein (P < 0.05). " 01/01/1990 - "One hundred and thirty-five children with lower UTI, diagnosed on the basis of fever (less than 38 degrees C), erythrocyte sedimentation rate (less than 25 mm/l h) and C-reactive protein (less than 20 micrograms/ml), were included in the study: 71 received 2 g of FT, 64 5 mg/kg of NM. Cure, defined as persistence of sterile urine up to 30 days after therapy, was reached in 80.2% of children in the FT group and in 81.2% of children in the NM group. " 11/01/2009 - "Three parameters emerged as independent factors for the prediction of neutropenic fever with complications in the multivariate regression analysis: platelet count (130-450 x 10(3) cells/mm(3)) <50 000 cells/mm(3), serum C-reactive protein (CRP, 0.1-1 mg/dl) >10 mg/dl and pulmonary infiltration on chest x ray. " 10/01/2009 - "When UTI was excluded, the risk factors for SBI were 1) C-reactive protein (CRP) level of > or =1.87 mg/dL and 2) fevers of > or =38.9 degrees C. " 09/01/2009 - "This group was characterized by a significantly higher maximal fever at presentation and higher absolute neutrophil count and C-reactive protein level than the children with simple disease. " Order ALL the reference details at left...

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8.	HDL Cholesterol
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Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Transplants (Transplant)
3.	Cardiopulmonary Resuscitation (CPR)
4.	Estrogen Replacement Therapy
5.	Fat-Restricted Diet (Diet, Fat Restricted)

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