Hyperemia

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3078 relevant articles (154 outcomes, 263 trials/studies) found for this Disease

Description: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).

Also Known As:

Active Hyperemia; Arterial Hyperemia; Passive Hyperemia; Reactive Hyperemia; Venous Congestion; Venous Engorgement; Congestion, Venous; Engorgement, Venous; Hyperemia, Active; Hyperemia, Arterial; Hyperemia, Passive; Hyperemia, Reactive; Hyperemias; Hyperemias, Reactive; Reactive Hyperemias

Relationship Network

Disease Context: Research Results

Cardiovascular Diseases: 20552

Vascular Diseases: 7633

Hyperemia: 3078

Related Diseases

1.	Pruritus (Itching)
2.	Ischemia
3.	Edema
4.	Pathologic Constriction (Stenosis)
5.	Inflammation

Experts

1.	Tousoulis, Dimitris: 4 articles (02/2008 - 10/2003)
2.	Stefanadis, Christodoulos: 4 articles (02/2008 - 10/2003)
3.	Antoniades, Charalambos: 4 articles (02/2008 - 10/2003)
4.	Nakagawa, K: 4 articles (10/2001 - 02/2000)
5.	Higashi, Y: 4 articles (10/2001 - 02/2000)
6.	Sasaki, S: 4 articles (10/2001 - 02/2000)
7.	Lee, Sung Gyu: 3 articles (04/2008 - 07/2004)
8.	Kim, Kyoung Won: 3 articles (04/2008 - 07/2004)
9.	Jalan, Rajiv: 3 articles (08/2007 - 06/2003)
10.	Harder, David R: 2 articles (08/2008 - 05/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperemia:

1.	Adenosine FDA LinkGeneric 06/01/2009 - "CONCLUSIONS: The results of this study suggest that an IC adenosine continuous infusion method via a microcatheter is safe and effective in inducing steady-state hyperemia and more potent and quicker in inducing optimal hyperemia than the standard IV infusion method." 08/01/2005 - "CONCLUSION: IC infusion of adenosine seems to be a safe and effective method of inducing maximal hyperemia for FFR measurement." 08/01/2005 - "BACKGROUND: Various methods are used to induce maximal hyperemia for physiologic studies, but the feasibility and efficacy of continuous intracoronary (IC) infusion of adenosine for measurement of fractional flow reserve (FFR) has not been well-defined. " 06/01/2009 - "We evaluated the efficacy of the intracoronary (IC) continuous adenosine infusion method via a microcatheter for inducing maximal coronary hyperemia. " 06/01/1990 - "Myocardial uptake and clearance of T1-201 in healthy subjects: comparison of adenosine-induced hyperemia and exercise stress." Order ALL the reference details at left...
2.	Malondialdehyde (Propanedial)IBA 06/01/2005 - "All 3 treatment arms significantly improved flow-mediated dilator response to hyperemia and reduced plasma levels of malondialdehyde relative to baseline measurements. " 03/20/2009 - "Amlodipine therapy significantly improved flow-mediated dilator response to hyperemia and reduced plasma malondialdehyde levels to a greater extent than placebo (P<0.001 and P=0.035). " 12/14/2004 - "All 3 treatment arms significantly improved flow-mediated dilator response to hyperemia and decreased plasma malondialdehyde and monocyte chemoattractant protein-1 levels relative to baseline measurements. " 06/01/2004 - "Compared with placebo, angiotensin II type-1 receptor blockers significantly improved the percent flow-mediated dilator response to hyperemia (p = 0.019 by analysis of variance [ANOVA]) and reduced plasma levels of malondialdehyde (p = 0.005 by ANOVA). " 09/15/2003 - "Compared with baseline, the step I diet significantly changed lipoprotein levels, significantly improved the percent flow-mediated dilation response to hyperemia by 32 +/- 7% (p <0.001), increased plasma levels of nitrate by 45 +/- 12% (p = 0.013), and lowered plasma levels of malondialdehyde by 7 +/- 4% (p = 0.011). " Order ALL the reference details at left...
3.	OxygenIBA 05/01/1975 - "As far as therapy is concerned in the prevention of vascular colaps and the improvement of the oxemia, oxygen is very useful when there is a venous congestion (clinically, X rays, and oxemia). " 11/01/1990 - "To determine whether extremity vasodilatory capacity may be augmented in older persons by endurance exercise training, lower leg blood flow and conductance were characterized plethysmographically at rest and during maximal hyperemia in 9 men and 10 women aged 64 +/- 3 (SD) yr before and after 31 +/- 6 wk of walking and jogging at 70-90% of maximal oxygen uptake for 45 min 3-5 days/wk. Maximal oxygen uptake expressed as milliliters per kilogram per minute improved 25% in men and 21% in women (P less than 0.01). " 01/01/1986 - "Our study indicates that inhibition of thromboxane synthesis has no effect on either resting intestinal blood flow or postprandial intestinal hyperemia but significantly enhances postprandial oxygen extraction and uptake. " 10/01/1980 - "The current study evaluated The role of oxygen supply to the mucosa in the absorptive hyperemia mechanism. " 08/01/1977 - "It can be concluded from this study that although oxygen tension does affect postocclusive reactive hyperemia, other factors such as myogenically induced vascular relaxation also contribute to the production of this phenomenon." Order ALL the reference details at left...
4.	Indomethacin (Indometacin)FDA LinkGeneric 03/01/1986 - "In 10 experiments, pretreatment with 50 mg indomethacin i.v. resulted in a significant reduction of the hyperemia reaction. " 07/01/1993 - "Indomethacin was also found to be effective in suppressing reactive hyperemia. " 01/01/2006 - "RESULTS: The intragastric administration of indomethacin induced hyperemia and hemorrhagic erosions in the rat stomachs. " 05/01/2000 - "Our results provide evidence that systemic application of Indomethacin leads to vasodilatation of the main arteriole of the villus in the rat ileum and hyperemia in the mucosa. " 08/01/1995 - "The effect of indomethacin was evaluated from the extent of cutaneous hyperemia. " Order ALL the reference details at left...
5.	Lipoproteins (Lipoprotein)IBA 01/23/1989 - "Since regional blood flow could affect the clearance of plasma lipoproteins, measurements were taken of forearm blood flow, forearm vascular resistance, and maximal forearm vasodilatory potential during reactive hyperemia. " 04/01/1980 - "These findings suggest the importance of employing physiological perfusion pressures in studies designed to examine hepatic lipoprotein metabolism and also suggest a possible mechanism in the pathogenesis of fatty change seen in the "nutmeg" liver of chronic venous congestion." 09/15/2003 - "Compared with baseline, the step I diet significantly changed lipoprotein levels, significantly improved the percent flow-mediated dilation response to hyperemia by 32 +/- 7% (p <0.001), increased plasma levels of nitrate by 45 +/- 12% (p = 0.013), and lowered plasma levels of malondialdehyde by 7 +/- 4% (p = 0.011). " 10/01/2004 - "The purpose of this study was to clarify whether coronary flow velocity reserve (CFVR), evaluated by adenosine 5'-triphosphate-induced hyperemia, is improved by single low-density lipoprotein (LDL) apheresis. " 08/01/2004 - "Simvastatin alone or combined with ramipril significantly changed lipoproteins, improved percent flow-mediated dilator response to hyperemia by 30+/-5% and 53+/-6%, respectively (P<0.001), and reduced plasma levels of malondialdehyde by 4+/-7% (P=0.026) and 25+/-4% (P<0.001), respectively. " Order ALL the reference details at left...
6.	Fibrinogen (Factor I)IBA 03/01/1985 - "Fibrinogen reduction in a slight increase in baseline CBF and the elimination of post-ischemic hyperemia at 24 hours. " 06/01/2005 - "Fenofibrate significantly improved percent flow-mediated dilator response to hyperemia by 48 +/- 5% (P < 0.001) and lowered plasma levels of high-sensitivity C-reactive protein (hsCRP) relative to baseline measurements from 0.80 to 0.70 mg/l (P = 0.001) and fibrinogen levels by 16 +/- 3% (P < 0.001). " 06/01/2004 - "RESULTS: Compared with diet alone, simvastatin significantly improved the percent flow-mediated dilator response to hyperemia and lowered plasma levels of tumor necrosis factor (TNF)-alpha, intercellular adhesion molecule type-1 (ICAM-1), serum levels of CRP, and fibrinogen (P<0.001, P<0.001, P=0.035, P<0.001 and P=0.014, respectively). " 01/01/2005 - "Plasma viscosity was assessed on a Coulter viscometer, fibrinogen by Clauss, vWf, D-dimer and soluble P selectin by ELISA, and FMD by reactive hyperemia. " 01/01/1990 - "Among those 13 characteristics detected as optimal amount there were thrombin time, thrombin coagulase time as parameter of haemostasis both before and after venous congestion, reptilase time prior to venous congestion and fibrinogen concentration after it. " Order ALL the reference details at left...
7.	Simvastatin (Zocor)FDA LinkGeneric 10/01/1996 - "For 18 of the same patients (11 taking simvastatin, 7 receiving placebo), forearm strain-gouge plethysmography was performed at baseline and after 4 weeks, both at rest and during reactive hyperemia. " 11/01/2004 - "Simvastatin and fenofibrate significantly improved the percent flow-mediated dilator response to hyperemia by 183+/-41% and by 30+/-7%, respectively (each P<0.001); however, simvastatin significantly improved more (P<0.001). " 08/01/2004 - "Ramipril alone or simvastatin combined with ramipril significantly improved the percent flow-mediated dilator response to hyperemia (both P<0.001), however, simvastatin combined with ramipril showed significantly more improvement than ramipril alone (P<0.001 by ANOVA). " 04/01/2000 - "After eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days), L-arginine amplified and sustained the hyperemia (38%) and increased absolute brain blood flow from 86 +/- 7 to 119 +/- 10 mL/100 g per minute. " 06/01/2004 - "RESULTS: Compared with diet alone, simvastatin significantly improved the percent flow-mediated dilator response to hyperemia and lowered plasma levels of tumor necrosis factor (TNF)-alpha, intercellular adhesion molecule type-1 (ICAM-1), serum levels of CRP, and fibrinogen (P<0.001, P<0.001, P=0.035, P<0.001 and P=0.014, respectively). " Order ALL the reference details at left...
8.	Nitroglycerin (Dynamite)FDA LinkGeneric 07/01/2005 - "Changes in vasodilator response to reactive hyperemia were significantly improved (p<0.01), while the response to nitroglycerin was not changed, suggesting the improvement of endothelial function. " 01/01/2005 - "Changes in vasodilator response to reactive hyperemia were significantly improved (p<0.01), while the response to nitroglycerin was not changed, suggesting the improvement of endothelial function. " 09/01/2007 - "Vascular reactivity was assessed at each phase of the study using high-frequency brachial artery ultrasound in response to flow-mediated hyperemia, cold pressor testing, and sublingual nitroglycerin. " 01/01/2005 - "MATERIAL AND METHODS: Clinical indices, exercise tolerance, endothelial function (the study of brachial artery in reactive hyperemia and sublingual intake of nitroglycerin) were studied in 30 patients with stable angina FC II-III before the treatment, 1 and 3 months after the treatment. " 01/01/2004 - "Reactive hyperemia and nitroglycerin tests were performed to study endothelial function. " Order ALL the reference details at left...
9.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 09/01/2001 - "In comparison to age-matched healthy subjects (v(max) = 1.46 +/- 0.52 mm/s), the patients with three-vessel disease showed a significant reduction in postischemic maximum erythrocyte velocity (v(max) = 0.85 +/- 0.55 mm/s), with a considerable shortening of the duration of reactive hyperemia. " 02/01/1992 - "Fortunately, an abnormal vessel connecting the left atrium with the superior vena cava relieved severe pulmonary venous congestion by diverting the blood flow. " 07/01/1992 - "This study indicates that the reactive hyperemia observed in the nonused internal mammary artery in the early postoperative period is mainly caused by the temporarily increased metabolic demand of the anterior thoracic wall and mediastinum, rather than by the metabolic demand of the anterior diaphragm and the contralateral rectus abdominis muscle after deprivation of their main nutritional vessel." 08/01/1990 - "In this study, 20 minutes of vessel occlusion resulted in brief (less than 1 hour) hyperemia, with no subsequent CT alteration and minimal random neuronal injury. " 07/01/2008 - "High-resolution ultrasonography (automated vessel-diameter measurements; eTRACKING system), a linear array transducer (13 MHz) and an arm holding device were used to measure the arterial diameter response to reactive hyperemia and sublingual nitroglycerine (NTG, 75 micrograms) in all subjects. " Order ALL the reference details at left...
10.	Ethanol (Ethyl Alcohol)IBA 04/01/1993 - "This study was designed to test the hypothesis that hyperemia after exposure to 2 M NaCl protects the gastric mucosa against damage caused by absolute ethanol by removing ethanol diffusing from the gastric lumen into the mucosa. " 11/07/2005 - "CONCLUSION: GSE exerts a potent gastroprotective activity against ethanol and WRS-induced gastric lesions via an increase in endogenous PG generation, suppression of lipid peroxidation and hyperemia possibly mediated by NO and CGRP released from sensory nerves." 07/01/2005 - "The intragastric administration of ethanol induced hyperemia and hemorrhagic erosions in the rat stomachs. " 02/01/2004 - "In the liver of the animals given ethanol, the degenerative changes such as extreme hyperemia, vacuolization in cells of portal areas, a dilation in sinusoids, mononuclear cell infiltration, a swelling in cisternae of granular endoplasmic reticulum and in mitochondrial cristae, an increase in smooth endoplasmic reticulum, many lipid vacuoles were observed both light and electron microscopically. " 01/01/2004 - "It was stated that 10-day administration of 20% ethanol causes hyperemia of the gastric mucous membrane and the decrease of secretory activity of the glands. " Order ALL the reference details at left...

Therapies and Procedures

1.	Lasers (Laser) 01/01/1985 - "In response to venous congestion, capillary flow rate falls drastically, whereas Laser-Doppler flow is much less dramatically reduced. " 02/01/1991 - "The basic values of laser-Doppler-fluxmetry (LDF) showed a significant reduction in the intensity of hyperemia in the patients from those in the normal controls; this reaction depended on the visual degree of the dermographic blanching effect (white, delayed white, indifferent, pale-red). " 09/01/2000 - "Laser Doppler flowmetry (LDF) is a noninvasive method to monitor skin perfusion and is very useful in studying reactive hyperemia signals. " 09/10/2008 - "In this study we used mechanical stimulation to induce oligemia and hyperemia, in surgically prepared cats and rats, using laser Doppler probes to measure the cerebral blood flow and single cell cortical recording to measure the spike/neuronal burst, both generated as a consequence of CSD. " 01/01/2008 - "In this study, we aimed to characterize the "effective" occlusion duration needed to elicit sufficient postocclusive hyperemia (PORH) responses in forearm skin using laser Doppler fluximetry (LDF), in subjects with differing age, gender and menstrual phases. " Order ALL the reference details at left...
2.	Transplants (Transplant) 03/01/1995 - "Although the maximal time-averaged peak velocity during hyperemia was significantly greater in new than in old arterial grafts or new or old vein grafts (47 +/- 17 vs. 40 +/- 7, 31 +/- 8 and 34 +/- 12 cm/s, respectively, p < 0.01), the flow reserve of new arterial grafts was significantly smaller than that of the other three groups (1.8 +/- 0.3 vs. 2.6 +/- 0.3, 2.8 +/- 0.5 and 3.0 +/- 0.6, respectively, p < 0.01) because the baseline time-averaged peak velocity of these new grafts was far greater than that of the other groups. " 10/01/2007 - "Angiography and pressure measurement at the proximal and distal portions of the left internal thoracic artery graft during maximal hyperemia with a pressure guide wire were performed at 1 month (early study) and 6 months (late study) after surgical intervention. " 11/01/2006 - "According to the results of this study, minimal modifications of the transection line can provide significant increases in functional volumetric parameters by avoiding venous congestion in the marginal zone of the graft, drained by the middle hepatic vein." 11/01/2009 - "High-resolution, B-mode ultrasound scans were used to measure vein graft diameter before and 1 minute after reactive hyperemia (RH) to determine FMD. " 06/01/2009 - "RESULTS: At 1 week after implantation of the matrix material, a small number of inflammatory cells and lymphocytic infiltration were observed around the graft, with mild hyperemia in the proliferative capillaries and mild inflammatory responses. " Order ALL the reference details at left...
3.	Microspheres (Microsphere) 01/01/1984 - "We measured velocity of blood flow and pial artery diameter to characterize the time course of reactive hyperemia and used microspheres to study regional blood flow in the brain. " 12/19/1977 - "[Study of the coronary arteriole bed at rest and during hyperemia by selective coronary scintigraphy with labeled microspheres]" 10/31/2006 - "During hyperemia alone, LCx probe and microsphere flows and MCE-derived red cell velocity increased from baseline (30+/-14 versus 125+/-62 mL/min, P<0.0005; 1.5+/-0.5 versus 6.6+/-2.0 mL x min(-1) x g(-1), P<0.0005; and 0.53+/-0.14 versus 0.96+/-0.45 second(-1), P=0.030, respectively); intramyocardial blood volume was unchanged. " 11/01/2004 - "The pro-arteriogenic effect of MCP-1 was confirmed by flow measurements during reactive hyperemia, as demonstrated by increased flow ratio (PBS 0.56+/-0.07 vs. MCP-1 0.77+/-0.06, no unit, p<0.0001), ankle-brachial index and microsphere-based conductance measurements (PBS 50.8+/-2.1 vs. MCP-1 225.8+/-8.8 ml/min/100 mm Hg, p<0.001). " 11/01/2002 - "At 5, 15 and 30 weeks of age, ten rats in each group were subjected to systemic and coronary hemodynamic measurements using the colored microsphere technique before and during maximal coronary hyperemia and histological assessment with Azan-Mallory stain of the coronary arterioles. " Order ALL the reference details at left...
4.	Replantation 05/01/1985 - "An experimental replantation model utilizing the rabbit ear was used to study the extreme example of venous congestion: absent venous drainage in the replanted part. " 03/01/2008 - "The failed replantation in this series was the case where only arterial revascularization was performed, which resulted in venous congestion. " 04/01/2007 - "Especially venous congestion is decreased using hirudo medicinalis application such as following replantation of amputated fingers or congested flaps. " 01/01/2005 - "Among these replantations, seven fingers (43.8 percent) showed postoperative venous congestion and five fingers were reoperated on with delayed venous drainage under digital block. " 05/01/2003 - "One week after replantation, the patient returned for treatment of venous congestion of an area to the opposite side of the forehead partial transection, with repair of the left superficial temporal vein, also. " Order ALL the reference details at left...
5.	Amputation 06/01/1995 - "A rabbit auricular amputation model was used to study the relative effects of arterial insufficiency (AI) and venous congestion (VC) on composite graft survival. " 07/01/2001 - "The authors present the case of a 16-year-old patient with a sagittal amputation of the radial aspect of the right thumb, who manifested at the time of surgery marked venous engorgement of a reverse-flow radial forearm flap. " 02/01/1997 - "For amputations of zone DP-IIA, special treatment is not necessary for venous congestion, and for those of zone DP-IIB partial resection of the nail is done if necessary. " 01/01/1985 - "The appearance of the hyperemia at 35 cm above the right atrium will allow healing of local ischemic lesions and at the height of 45 cm or above indicates a zone at which amputation may be carried out successfully. " 02/01/1981 - "Of those without this degree of hyperemia, 83% (five of six) will require amputation. " Order ALL the reference details at left...

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