Pituitary Dwarfism

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192 relevant articles (1 outcomes, 13 trials/studies) found for this Disease

Description: A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

Also Known As:

Dwarfism, Pituitary; Dwarfism, Growth Hormone Deficiency; Nanism, Pituitary; Pituitary Nanism; Growth Hormone Deficiency Dwarfism; Hypophysial Dwarf; Hyposomatotrophic Dwarfism; Pituitary Dwarf

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Syndrome
2.	Dwarfism
3.	Infection
4.	Acromegaly
5.	Empty Sella Syndrome

Experts

1.	Mol, J A: 3 articles (12/2006 - 01/2000)
2.	Kooistra, H S: 3 articles (12/2006 - 01/2000)
3.	Hanson, J M: 1 article (12/2006)
4.	Leegwater, P A J: 1 article (12/2006)
5.	Meij, B P: 1 article (12/2006)
6.	Leiser, Scott F: 1 article (11/2006)
7.	Miller, Richard A: 1 article (11/2006)
8.	Salmon, Adam B: 1 article (11/2006)
9.	De Vliegher, S P: 1 article (08/2006)
10.	Van Ham, L M L: 1 article (08/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pituitary Dwarfism:

1.	HormonesIBA 01/01/1995 - "In pituitary dwarfism, MRI reveals severe sella/pituitary gland and stalk hypoplasia with or without posterior pituitary ectopia, and empty sella, and this more frequently in patients with multiple pituitary hormone deficiency" 06/01/1983 - "Pituitary dwarfism that showed Perthes-like symptoms during thyroid hormone administration]" 05/19/1976 - "Pituitary dwarfism due to peripheral resistance to somatotropic hormone]" 01/01/1971 - "Value of radioimmunological determination of the somatotropic hormone in a series of children with low body height for the diagnosis of pituitary dwarfism]" 12/01/2006 - "Pituitary dwarfism in German shepherd dogs is characterized by combined pituitary hormone deficiency (CPHD) and intrapituitary cyst formation" Order ALL the reference details at left...
2.	GonadotropinsIBA 04/01/1992 - "The effects of hCG-hMG treatment in 13 boys with pituitary dwarfism associated with gonadotropin deficiency, were assessed" 06/01/1981 - "Females with pituitary dwarfism of the multiple pituitary hormone deficiency form have ovarian failure due to hypogonadotropism which would be expected to respond favorably to human gonadotropin treatment" 04/01/1992 - "Combined human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG) treatment in gonadotropin-deficient males with pituitary dwarfism." 06/01/1981 - "This is a description of a pituitary dwarf in whom pregnancy was achieved with gonadotropin therapy; its progress was followed regularly by hormone assays." 03/01/1990 - "Using pulsatile LH-RH administration, ovulation induction was performed in women with pituitary dwarfism (PD, n = 1), isolated gonadotropin deficiency (IGD, n = 5), secondary hypothalamic amenorrhea (gestagen negative (AM2, n = 10), positive (AM1, n = 5)), polycystic ovarian disease (PCO, n = 6) and anovulatory cycle (ANOV, n = 1)" Order ALL the reference details at left...
3.	Growth Hormone (Somatotropin)IBA 12/01/1985 - "In the last decade this work culminated in the close study of the Little Mouse with isolated growth hormone deficiency--thus exposing the panhypopituitary model (the human pituitary dwarf, Snell Smith mouse or hypophysectomised rat) as non-optimal models" 03/01/2008 - "Pituitary dwarfism causes short stature due to partial or complete inhibition of growth hormone (GH) secretion" 04/01/2006 - "The patient had no central nervous disturbance, was diagnosed with pituitary dwarfism during childhood and was treated at another hospital with growth hormone supplement from 5 to 14 years of age" 09/10/2005 - "CASE: A 37 year-old man had been treated for pituitary dwarfism during adolescence with contaminated growth hormone" 02/01/2000 - "The effect of growth hormone (GH) on the dentition has been described in children with pituitary dwarfism where teeth fail to form; those that do form tend to be reduced in size and the eruption potential is diminished" Order ALL the reference details at left...
4.	Human Growth Hormone (Saizen)FDA LinkGeneric 01/01/1975 - "The study has aimed at investigating the blastic transformation of peripheral blood lymphocytes in patients with pituitary dwarfism before, during and after the treatment with human growth hormone" 07/01/1965 - "Study of the effects of human growth hormone in a patient with pituitary dwarfism]" 10/01/1964 - "RESISTANCE TO HUMAN GROWTH HORMONE IN PITUITARY DWARFISM: CLINICAL AND IMMUNOLOGIC STUDIES." 02/01/2004 - "1) We reported on the head hair concentration of the above-mentioned elements from pituitary dwarfism (human growth hormone deficient) patients" 04/01/1987 - "Treatment of pituitary dwarfism with authentic recombinant human growth hormone (SM-9500)." Order ALL the reference details at left...
5.	Somatomedins (Somatomedin)IBA 09/01/1975 - "Pituitary dwarfism in german shepherd dogs: studies on somatomedin activity." 01/01/1981 - "Inasmuch as the medium was supplemented with 10% fetal calf serum, which presumably contains somatomedin, these data suggest that the Dw/Dw mutant cannot be considered simply a model for pituitary dwarfism" 01/01/1976 - "Pituitary dwarfism is a genetically heterogeneous group of disorders associated with a variety of pathogenetic mechanisms which may involve any level of the hypothalamic-pituitary-somatomedin-peripheral tissue axis" 07/01/1963 - "Sulfation factor measurement as an aid in the recognition of pituitary dwarfism." 10/20/1984 - "Somatomedin (bioassay) response to long-term growth hormone treatment of idiopathic pituitary dwarfism]" Order ALL the reference details at left...
6.	Growth Hormone-Releasing Hormone (Somatotropin Releasing Hormone)IBA 03/01/1988 - "Secretion of growth hormone-releasing hormone in patients with idiopathic pituitary dwarfism and acromegaly." 01/01/1987 - "Effect of somatocrinin (GRF) on the secretion of growth hormone in pituitary dwarfism]" 12/01/1984 - "Plasma growth hormone responses to repetitive administrations of growth hormone releasing factor in patients with pituitary dwarfism." 01/01/1976 - "Further pathologic studies of the hypothalamus and pituitary in pituitary dwarfism; analysis of growth hormone and somatomedin cellular receptors; and elucidation of the structure of growth hormone releasing factor and techniques for its synthesis and assay should allow for the delineation of the specific pathogenetic mechanism in each of these syndromes." Order ALL the reference details at left...
7.	Pituitary HormonesIBA 01/01/1991 - "The purpose of this study was to determine whether the MR findings of idiopathic pituitary dwarfism correlated with a clinical history of perinatal abnormalities and abnormal levels of pituitary hormones" 03/20/1995 - "The possibility of pituitary dwarfism during her youth and a gradual postpartum reduction of other pituitary hormones may have caused an impairment of the hypothalamo-pituitary-adrenal axis." Order ALL the reference details at left...
8.	GhrelinIBA 08/01/2006 - "Ghrelin-stimulation test in the diagnosis of canine pituitary dwarfism." 08/01/2006 - "This study investigated whether ghrelin, a potent releaser of growth hormone (GH) secretion, is a valuable tool in the diagnosis of canine pituitary dwarfism" Order ALL the reference details at left...
9.	Dehydroepiandrosterone SulfateIBA 09/20/1981 - "The study of serum dehydroepiandrosterone sulfate levels in normal children and children with pituitary dwarfism (author's transl)]" Order ALL the reference details at left...
10.	Nonesterified Fatty Acids (NEFA)IBA 12/01/1963 - "STUDY OF THE PLASMA FREE FATTY ACIDS IN HYPOTHALAMO-PITUITARY NANISM TREATED AND UNTREATED BY GROWTH HORMONE.]" Order ALL the reference details at left...

Therapies and Procedures

1.	Colonic Pouches (S Pouch) 07/01/1980 - "Pituitary dwarfism in the 13-month-old bitch can be ascribed to the persistence of one end of the ductus craniopharyngeus, Rathke's pouch" Order ALL the reference details at left...
2.	Cesarean Section (Caesarean Section) 07/01/1998 - "Anesthesia for cesarean section in a pituitary dwarf." Order ALL the reference details at left...
3.	Anesthesia 07/01/1998 - "Anesthesia for cesarean section in a pituitary dwarf." Order ALL the reference details at left...

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