Growth Hormone (Somatotropin)

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9641 relevant articles (239 outcomes, 847 trials/studies) found for this Bio-Agent

Description: A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.

Also Known As:

Somatotropin; Recombinant Somatotropins; Growth Hormone, Pituitary; Growth Hormones Pituitary, Recombinant; Pituitary Growth Hormones, Recombinant; Recombinant Growth Hormones; Recombinant Pituitary Growth Hormones; Somatotropins, Recombinant; Growth Hormones, Recombinant; Recombinant Somatotropin; Growth Hormone, Recombinant; Pituitary Growth Hormone; Recombinant Growth Hormone; Somatotropin, Recombinant

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 46253

Peptide Hormones: 377

Pituitary Hormones: 370

Anterior Pituitary Hormones: 108

Growth Hormone: 9641

Human Growth Hormone: 1312

acceleratory factor from growth hormone: 195

bovine growth hormone: 61

human HGH-V protein: 26

Met-human growth hormone: 11

S-carboxymethylsomatotropin: 6

somatotropin (177-191): 4

sometribove: 4

somatotropin (6-13): 2

human growth hormone 1-15: 1

pregrowth hormone: 1

somatotropin (1-134): 1

Ala(165)- somatotropin

cataglykin

cyclo(phenylalanyl-tryptophyl-lysyl-threonyl-4-(aminomethyl)phenylacetic acid)

cyclo-(phenylalanyl-tryptophyl-lysyl-threonyl-3-(aminomethyl)phenylacetic acid)

cyclo-phenylalanyl-tryptophyl-lysyl-threonyl-2-(aminomethyl)phenylacetic acid

des(1-6,14)- human growth hormone

di-(4-azidophenacyl) (182,189)- somatotropin

E 117 peptide

gamma-lactam(11) human growth hormone (6-13)

glycosylated somatotropin

human G119R protein

human G120R protein

human growth hormone isohormone D

human growth hormone isohormone E

iodinated somatotropin

L 117 peptide

leucyl(117)-arginyl(119)-aspartyl(122)- somatotropin

methione-equine growth hormone

N(alpha)-acetylsomatotropin (7-13)

newt growth hormone

S-carbamidomethyl human growth hormone

Salmo salar growth hormone type I

salmon growth hormone type II

somatotropin (1-43)

somatotropin (108-129)

somatotropin (134-154)

somatotropin (135-191)

somatotropin (176-191)

somatotropin (44-191)

somatotropin (44-91)

somatotropin (54-95)

somatotropin (73-128) glycinamide

somatotropin (75-120)

somatotropin fragment 77-107

somatotropin fragment 87-124

somatotropin fragment 96-133

somatotropin sulfoxide

somfasepor

synthetic 2-CAP protein

Amino Acids, Peptides, and Proteins

Peptides: 16375

Peptide Hormones: 377

Pituitary Hormones: 370

Anterior Pituitary Hormones: 108

Growth Hormone: 9641

Human Growth Hormone: 1312

acceleratory factor from growth hormone: 195

bovine growth hormone: 61

human HGH-V protein: 26

Met-human growth hormone: 11

S-carboxymethylsomatotropin: 6

somatotropin (177-191): 4

sometribove: 4

somatotropin (6-13): 2

human growth hormone 1-15: 1

pregrowth hormone: 1

somatotropin (1-134): 1

Ala(165)- somatotropin

cataglykin

cyclo(phenylalanyl-tryptophyl-lysyl-threonyl-4-(aminomethyl)phenylacetic acid)

cyclo-(phenylalanyl-tryptophyl-lysyl-threonyl-3-(aminomethyl)phenylacetic acid)

cyclo-phenylalanyl-tryptophyl-lysyl-threonyl-2-(aminomethyl)phenylacetic acid

des(1-6,14)- human growth hormone

di-(4-azidophenacyl) (182,189)- somatotropin

E 117 peptide

gamma-lactam(11) human growth hormone (6-13)

glycosylated somatotropin

human G119R protein

human G120R protein

human growth hormone isohormone D

human growth hormone isohormone E

iodinated somatotropin

L 117 peptide

leucyl(117)-arginyl(119)-aspartyl(122)- somatotropin

methione-equine growth hormone

N(alpha)-acetylsomatotropin (7-13)

newt growth hormone

S-carbamidomethyl human growth hormone

Salmo salar growth hormone type I

salmon growth hormone type II

somatotropin (1-43)

somatotropin (108-129)

somatotropin (134-154)

somatotropin (135-191)

somatotropin (176-191)

somatotropin (44-191)

somatotropin (44-91)

somatotropin (54-95)

somatotropin (73-128) glycinamide

somatotropin (75-120)

somatotropin fragment 77-107

somatotropin fragment 87-124

somatotropin fragment 96-133

somatotropin sulfoxide

somfasepor

synthetic 2-CAP protein

Experts

1.	Colao, Annamaria: 15 articles (09/2008 - 04/2003)
2.	Lombardi, Gaetano: 12 articles (09/2008 - 04/2003)
3.	Pivonello, Rosario: 10 articles (09/2008 - 04/2003)
4.	Giustina, A: 9 articles (07/2008 - 02/2000)
5.	De Marinis, L: 9 articles (07/2008 - 02/2000)
6.	Ranke, M B: 9 articles (03/2007 - 01/2000)
7.	Ghigo, E: 9 articles (04/2006 - 05/2000)
8.	Hardin, Dana S: 8 articles (08/2008 - 05/2002)
9.	Bianchi, A: 7 articles (07/2008 - 02/2000)
10.	Otten, B J: 7 articles (06/2008 - 01/2001)

Related Diseases

1.	Acromegaly 04/19/2004 - "While trans-sphenoidal surgery remains first-line treatment for acromegaly, drug treatment has an important role in controlling residual growth-hormone excess and, in some circumstances, as first-line treatment. " 06/01/1999 - "Radiotherapy continues to have an important role in the treatment of acromegaly and is particularly effective at halting tumour growth, causing tumour shrinkage and reducing growth hormone (GH) concentrations in the long term. " 05/01/1990 - "Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy." 04/01/1983 - "Following successful treatment of acromegaly (growth hormone less than 5 micrograms/l) there was a significant reduction in skin thickness (P less than 0.02 males: P less than 0.01 females). " 10/01/1995 - "Treatment of acromegaly is effective in reversing the reduced life-span of patients only when serum growth hormone (GH) concentrations are lowered to less than 2.5 micrograms/l. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 11/01/2000 - "The symptoms resolved over 2 months as the tumor shrunk in size and growth hormone was dramatically reduced." 07/01/2003 - "All six patients with growth hormone-producing tumors responded well to therapy. " 09/01/2004 - "Factors that affect final height and change in height standard deviation scores in survivors of childhood cancer treated with growth hormone: a report from the childhood cancer survivor study." 12/01/2000 - "Design and interpretation of studies of the risk of cancer and other long-term morbidity and mortality after growth hormone treatment." 07/01/1995 - "Failure of anabolism in malnourished cancer patients receiving growth hormone: a clinical research center study." Order ALL the reference details at left...
3.	Turner Syndrome (Turner's Syndrome) 09/01/1999 - "The efficacy of long-term growth hormone treatment and the optimal treatment modalities in Turner's syndrome are still controversial. " 04/01/1996 - "BACKGROUND: Since growth hormone is effective in increasing the height of girls with Turner's syndrome, it is important to dispose of growth and bone maturation curves in a large number of untreated patients. " 07/01/1992 - "STUDY OBJECTIVE--To determine the influence of the injection frequency and the initial bone age on the efficacy of treatment with biosynthetic growth hormone in Turner's syndrome. " 04/01/2002 - "CONCLUSIONS: Genetic investigation is essential in the management of patients with SS, especially for girls suspected of having Turner syndrome, in which growth hormone treatment has shown to improve final height. " 09/01/1999 - "Efficacy of long-term growth hormone treatment in Turner's syndrome. " Order ALL the reference details at left...
4.	Body Weight (Weight, Body) 05/01/1998 - "RESULTS: There was a significant reduction in the percentage of body fat after growth hormone treatment; height velocity doubled during treatment; body weight did not change significantly when expressed as an SDS. " 09/01/1994 - "The effect of a high (33 degrees C) compared to a normal (23 degrees C) ambient temperature on the pulsatile release of growth hormone (GH) has been studied in 4-week-old, cannulated male meat-type chickens selected for high body weight (GL line) or for improved feed efficiency (FC line). " 09/01/1994 - "The effect of environmental temperature on episodic growth hormone release of meat-type chickens selected for 6 week body weight or for improved feed efficiency between 3 and 6 weeks of age." 03/01/1975 - "The mean plasma concentration of growth hormone in the normal dog after overnight fast is 1.75 plus or minus .17 ng/ml. Exogenous cGH was cleared from the plasma of both the normal and hypophysectomized dog with a mean half-life of 25.6 plus or minus 1.0 min and was distributed in a volume equal to 8.9% of the body weight. " 04/01/2007 - "In the present study, GHR and MA-GHBP content in liver were analyzed using mutant and transgenic mice expressing different concentrations of growth hormone to evaluate the correlation between GH levels, body weight (BW), GHR and MA-GHBP expression. " Order ALL the reference details at left...
5.	Pituitary Neoplasms (Pituitary Adenoma) 09/01/2001 - "Although it seems to be very effective in controlling growth and secretion of the growth hormone-secreting pituitary adenomas, there is a chance that some major risks from gamma knife radiosurgery might occur. " 05/01/2007 - "Radiosurgery of growth hormone-producing pituitary adenomas: factors associated with biochemical remission." 08/01/2007 - "CONCLUSIONS: This study reports on the unusual case of a patient with mild short stature, who acquired GHD in late adulthood due to a non-secreting pituitary adenoma and get additionally diagnosed for pre-existing growth hormone insensitivity due to a formerly in two short statured patients described, single, heterozygous, non-synonymous mutation in the GHR. " 10/01/1998 - "Detection of gsp oncogene in growth hormone-secreting pituitary adenomas and the study of clinical characteristics of acromegalic patients with gsp-positive pituitary tumors." 07/01/1997 - "Endocrine studies indicated that her pituitary tumor was active with hyperproduction of growth hormone. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Insulin-Like Growth Factor I (IGF-1)
2.	Insulin (Novolin)
3.	Glucose (Dextrose)
4.	Hormones
5.	Somatostatin (Somatotropin Release-Inhibiting Factor)
6.	Octreotide (Sandostatin)
7.	Prolactin
8.	Hydrocortisone (Cortisol)
9.	Adrenocorticotropic Hormone (ACTH)
10.	Glucagon (Glukagon)

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Drug Therapy (Chemotherapy)
3.	Length of Stay
4.	Injections
5.	Cranial Irradiation

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