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Gonadotropin-Releasing Hormone (GnRH)

A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Also Known As:
GnRH; Gonadorelin; Luteinizing Hormone Releasing Hormone; LFRH; Gonadoliberin; LHRH; LH-RH; Cystorelin; Dirigestran; Factrel; Gn-RH; Gonadorelin Acetate; Gonadorelin Hydrochloride; Kryptocur; LH-Releasing Hormone; LHFSH Releasing Hormone; LHFSHRH; FSH Releasing Hormone; Gonadotropin Releasing Hormone; LH FSH Releasing Hormone; LH Releasing Hormone; Releasing Hormone, LHFSH; FSH-Releasing Hormone; LH-FSH Releasing Hormone; Luliberin; Luteinizing Hormone-Releasing Hormone; 5-oxoPro-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (human or pig)
Networked: 10670 relevant articles (838 outcomes, 1561 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Schally, Andrew V: 69 articles (06/2021 - 02/2002)
2. Pitteloud, Nelly: 43 articles (01/2021 - 01/2002)
3. Crowley, William F: 35 articles (01/2020 - 01/2002)
4. Millar, Robert P: 34 articles (10/2021 - 03/2002)
5. Emons, Günter: 34 articles (01/2021 - 01/2002)
6. Gründker, Carsten: 33 articles (01/2021 - 01/2002)
7. Smith, Matthew R: 30 articles (03/2014 - 02/2002)
8. Seminara, Stephanie B: 27 articles (01/2022 - 01/2002)
9. Tsukamura, Hiroko: 25 articles (01/2022 - 10/2005)
10. Quinton, Richard: 24 articles (01/2022 - 04/2002)

Related Diseases

1. Endometriosis
2. Prostatic Neoplasms (Prostate Cancer)
3. Precocious Puberty
4. Neoplasms (Cancer)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Gonadotropin-Releasing Hormone (GnRH)
2. Hormones (Hormone)
3. Androgens
4. 6-chloro-2-(1-piperazinyl)pyrazine (CPP)
5. Estrogens (Estrogen)
6. Gonadotropins
7. Androgen Antagonists (Antiandrogens)
8. Leuprolide (Lupron)
9. Buserelin (Suprefact)
10. Testosterone (Sustanon)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Castration
4. Aftercare (After-Treatment)
5. Orchiectomy (Orchidectomy)