|1.||Takai, Toshiro: 4 articles (05/2013 - 07/2005)|
|2.||Ogawa, Hideoki: 4 articles (05/2013 - 07/2005)|
|3.||Okumura, Ko: 4 articles (05/2013 - 07/2005)|
|4.||Li, Chaopin: 3 articles (01/2015 - 01/2014)|
|5.||Gold, Diane R: 2 articles (10/2015 - 03/2006)|
|6.||Litonjua, Augusto A: 2 articles (10/2015 - 03/2006)|
|7.||Weiss, Scott T: 2 articles (10/2015 - 03/2006)|
|8.||Li, Chao-pin: 2 articles (02/2015 - 08/2014)|
|9.||Jiang, Yuxin: 2 articles (01/2015 - 01/2014)|
|10.||Magnan, Antoine: 2 articles (01/2014 - 06/2012)|
|1.||Asthma (Bronchial Asthma)
01/01/2015 - "We detected the concentration of dust mites allergen (Der f1 & Der p1) in the air of different places before and after the starting of air-conditioners in Wuhu City, Anhui, China, and to discuss the relation between the dust mites allergen in air-conditioner filters and the asthma attack. "
03/01/2014 - "The Der f 1 exposure level from mattress dusts in summer but no others was negatively correlated with asthma control level (r = -0.318, P = 0.036). "
03/01/2010 - "Bronchial asthma, sensitisation and exposure to Der p1 and Der f1 in an Andean Ecuadorian school."
08/01/2007 - "The concentration of Der f1 and Der 2 at both asthma families and normal families was higher than 2 microg/g, an allergen concentration threshold. "
08/01/2007 - "From the filter-net dust of air conditioner in family with allergic asthma patient, the concentration of Der p1, Der f1 and Der 2 was (0.52 +/- 0.19), (3.34 +/- 0.63), (2.53 +/- 0.65) microg/g dust, while that of normal families was (1.30 +/- 0.35), (5.16 +/- 0.92), (3.47 +/- 1.13) microg/g dust respectively. "
12/01/2000 - "The availability of a highly purified recombinant Der f 1 will facilitate experimental and clinical studies of mite allergy."
01/01/1991 - "It is anticipated that the availability of recombinant Der f I will facilitate epitope mapping studies and studies of T-cell function in mite allergy by providing high levels of pure allergen."
01/01/2015 - "Der f 1 level in dust was associated with daytime breathlessness (p= 0.033) especially among those with HDM allergy. "
03/01/2011 - "All of the 42 dust samples measured by both ELISAs had the Der f 1 levels higher than 2 mg per gram of fine dust which is the HDM allergy sensitizing level. "
02/01/2004 - "An ecological analysis was conducted to show the regression of the geometric mean allergen level, using the highest household level, against asthma symptom and severity prevalence data from the International Study of Asthma and Allergies in Childhood, Phase I. Among children aged 13-14 yr, the change in asthma symptom prevalence was associated with per unit change in Der p1 microg/g (1.08, 95% CI 0.10-2.06) and Der 1 microg/g (Der p1 + Der f1) (0.64, 95% CI 0.02-1.26). "
|3.||Atopic Dermatitis (Atopic Eczema)
01/01/2006 - "Reported prevalence of current (in the last 12 months) itchy skin rash was significantly associated with exposure to Der f 1 only (OR 2.4, P < 0.003); also a diagnosis of atopic eczema on the day of investigation was positively associated with Der f 1 only (OR 1.8, P = 0.14). "
09/01/2015 - "This study aimed to investigate the sensitization profiles of Korean HDM allergic subjects suffering from respiratory allergy and atopic dermatitis (AD) to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20. "
01/15/2002 - "microceras extract, and similarly to the purified 98/104kD allergen compared to Der f 1 and Der f 2. The close association between serological findings and PBMC proliferation implies that the 98/104kD HDM protein is a major target of immune recognition and that T-cells also participate in the pathogenesis of canine atopic dermatitis by supporting IgE production."
01/15/2002 - "Human atopic dermatitis is associated with the HDM derived allergens Der f 1 and 2, and Der p 1 and 2. Serological data, however, suggest that a 98/104kD protein is the most important allergen in dogs with atopic dermatitis. "
09/01/2009 - "The results suggest that mite-derived serine protease activity may contribute to the pathogenesis of atopic dermatitis by activating keratinocytes via PAR-2 activation but cysteine protease activity of Der f 1 and Der p 1 acts via another mechanism."
01/01/2014 - "The aim of the study is to evaluate the effects of DNA immunization with Der f1 allergen specific DNA on allergic sensitization, inflammation and respiratory function in mice. "
01/01/2008 - "Proteolytic activity of recombinant Der f 1 and Der p 1 upregulates GM-CSF and IL-8 release from keratinocytes in vitro, suggesting possible contributions to sensitization through the skin and the perpetuation of atopic dermatitis, as well as a homeostatic role for cystatin A against inflammation of the skin."
10/15/2009 - "Of all the cytokines and chemokines investigated in CPEK, transcription levels of GM-CSF, IL-8/CXCL8 and TNF-alpha mRNA were significantly enhanced by stimulation with Der f 1. The present results suggest that Der f 1 can directly augment inflammatory cytokine and chemokine production from keratinocytes, and may initiate allergic inflammation independently of Type-I hypersensitivity."
01/01/2006 - "To evaluate the effects of vaccination with mixed naked DNA plasmids encoding Der p 1, Der p 2, Der p 3, Der f 1, Der f 2, and Der f 3, the major house dust mite allergens on the allergic inflammation to the whole house dust mites (HDM) crude extract. "
10/01/2007 - "A double blind, placebo-controlled cross over trial was conducted on 15 adult persistent rhinitis sufferers (diagnosed positive to Der p1 and/or Der f1 by SPT) and who had symptoms over the previous 2 years. "
04/01/2011 - "Thirty-one D farinae-sensitive adults with allergic rhinitis with or without mild intermittent asthma were eligible for randomization to high-dose maintenance vaccine (n = 10, 4200 allergen units [approximately 70 μg of Der f 1/d]), low-dose maintenance vaccine (n = 10; 60 allergen units [approximately 1 μg of Der f 1/d]), or placebo (n = 11) over 12 to 18 months. "
05/01/2015 - "House dust mite (Dermatophagoides farinae) allergen Der f1 is one of the most important indoor allergens associated with asthma, eczema and allergic rhinitis in humans. "
|1.||invariant chain (Ii-Key)
|2.||Dermatophagoides pteronyssinus antigen p 1
|4.||Dermatophagoides farinae antigen f 2
|5.||allergen Bla g 1
|6.||DNA (Deoxyribonucleic Acid)
|7.||Messenger RNA (mRNA)
|8.||Dust (House Dust)
|10.||Immunoglobulin E (IgE)