Hydrolases

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580 relevant articles (5 outcomes, 34 trials/studies) found for this Bio-Agent

Description: Any member of the class of enzymes that catalyze the cleavage of the substrate and the addition of water to the resulting molecules, e.g., ESTERASES, glycosidases (GLYCOSIDE HYDROLASES), lipases, NUCLEOTIDASES, peptidases (PEPTIDE HYDROLASES), and phosphatases (PHOSPHORIC MONOESTER HYDROLASES). EC 3.

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1

Enzymes: 25587

Hydrolases: 580

Peptide Hydrolases: 5762

Epoxide Hydrolases: 293

Glycoside Hydrolases: 228

Esterases: 227

Pancreatin: 119

fumarylacetoacetase: 96

arginine deiminase: 68

Adenosylhomocysteinase: 55

N-sulfoglucosamine sulfohydrolase: 54

protein-arginine deiminase: 50

adenosylmethionine hydrolase: 4

plasmalogenase: 4

peptidylarginine deiminase type IV: 3

3-hydroxykynureninase: 2

O-alkyl cleavage enzyme: 2

2-hydroxy-6-oxo-2,4-heptadienoate hydrolase: 1

halothane dehalogenase: 1

histidine triad protein: 1

phosphonopyruvate hydrolase: 1

phosphoryl oxime hydrolase: 1

phosphorylcholine hydrolase: 1

tyrosine dehalogenase: 1

13 kDa phosphoamidase

2,3,5,6-tetrachloro-4-hydroquinone reductive dehalogenase

2,4,6-trichlorophenol reductive dehalogenase

2,6-dichloro-4-hydroquinone chlorohydrolase

2,6-dioxo-6-phenylhexa-3-enoate hydrolase

2-amino-delta(2)-thiazoline-4-carboxylate hydrolase

2-haloacid dehalogenase

2-hydroxy-6-keto-6-phenylhexa-2,4-dienoic acid 5,6-hydrolase

2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4-dienoic acid hydrolase

3,4-dihydrocoumarin hydrolase

3-chloro-4-hydroxybenzoate reductive dehalogenase

3-chlorobenzoate dehalogenase

4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoic acid hydrolase

4-chlorobenzoate dehalogenase

4-chlorobenzoyl coenzyme A dehalogenase

6-oxocamphor hydrolase

6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase

acetylpyruvate hydrolase

Acid Anhydride Hydrolases

adenosine 5'-phosphoramidate hydrolase

ADP-ribosyl protein hydrolase C

agmatine deiminase

Aminohydrolases

Arabidopsis PLP2 protein

atrazine chlorohydrolase

Bacillus megaterium peptidoglycan-lytic enzyme

Bacillus subtilis CwlJ protein

Bacillus subtilis EE57C protein

Bacillus subtilis tagH protein

bacteria LigY hydrolase

Bionectria ochroleuca Zhd101 protein

canavanine hydrolase

chicken AMP-lysine hydrolase

cis-3-chloroacrylic acid dehalogenase

Complement Activating Enzymes

cyanidase

cyanide dihydratase

cyclamate sulphamidase

deoxylimonin hydrolase

dimethoate-degrading enzyme

E coli AstB protein

E coli MhpC protein

E coli OmpX protein

E coli phosphotriesterase homology protein

E coli YcaC protein

fluoroacetate-specific dehalogenase

formiminoglutamate deiminase

fumarylpyruvate hydrolase

gluculase

haloacetate dehalogenase

haloalcohol dehalogenase

haloalkane dehalogenase

halohydrin dehalogenase

HC-toxin synthetase 1

homocysteinase

human ABHD2 protein

human C11orf54 protein

human iodotyrosine dehalogenase 1

isoleucine hydroxylase

lysoplasmalogenase

lysyl-(N-epsilon-5'-phospho) adenosyl phosphoamidase

maleylpyruvate hydrolase

mammals histidine triad nucleotide-binding protein

Mesorhizobium loti 2-(acetamidomethylene)succinate hydrolase

methylthiolase

mouse ABHD12 protein

Experts

1.	Devaki, Thiruvengadam: 3 articles (12/2006 - 05/2003)
2.	Borchardt, Ronald T: 2 articles (04/2008 - 05/2007)
3.	Li, Qing-Shan: 2 articles (04/2008 - 05/2007)
4.	Kuczera, Krzysztof: 2 articles (04/2008 - 05/2007)
5.	Fang, Jianwen: 2 articles (04/2008 - 05/2007)
6.	Schowen, Richard L: 2 articles (04/2008 - 05/2007)
7.	Middaugh, C Russell: 2 articles (04/2008 - 05/2007)
8.	Cai, Sumin: 2 articles (04/2008 - 05/2007)
9.	Sathish, Venkatachalem: 2 articles (09/2003 - 05/2003)
10.	Ebenezar, Kesavarao Kumar: 2 articles (09/2003 - 05/2003)

Related Diseases

1.	Mucolipidoses (Sialidosis) 12/17/2004 - "We report that fibroblasts isolated from patients affected with inclusion-cell disease (ICD), having a deficient activity of almost all lysosomal hydrolases, are resistant to the toxic effect of TNF. " 07/01/1995 - "The abnormality in the intracellular transport of the acid hydrolases into the lysosomes in I-cell disease is briefly reviewed and discussed." 12/01/1989 - "Furthermore, the rank order of hydrolases in the IPM is the same as that for hydrolases secreted (but not recaptured) by human fibroblasts in I-cell disease. " 10/01/1986 - "Lysosomal hydrolases in blood-derived macrophages of patients with I-cell disease." 11/08/1983 - "Complex glycosylated hydrolases are also produced by fibroblasts from patients with mucolipidosis I but an abnormal excretion is not apparent in this disorder. " Order ALL the reference details at left...
2.	Lysosomal Storage Diseases (Lysosomal Storage Disease) 04/01/2009 - "Inherited deficiencies of lysosomal hydrolases cause lysosomal storage diseases (LSDs) that are characterized by a progressive multisystemic pathology and premature death. " 12/01/1995 - "Lysosomal storage diseases are mainly caused by genetic defects that affect one or more of the lysosomal hydrolases, and result in accumulation of their undigested substrates in lysosomes, with profound pathological consequences. " 01/01/1993 - "However, mast cell cytoplasmic granules contain hydrolases similar to those found in lysosomes, but which differ from lysosomal hydrolases in exhibiting optimal activity at higher pH. We therefore examined by transmission electron microscopy the dermal mast cells in 58 biopsies of patients exhibiting 1 of 29 different lysosomal storage diseases. " 01/01/1987 - "The majority of lysosomal storage diseases results from genetic inability to express one or another of the many activities of the lysosomal hydrolases. " 12/01/1978 - "Plasma acid hydrolases in normal adults and children, and in patients with some lysosomal storage diseases." Order ALL the reference details at left...
3.	Protein Deficiency 09/01/1984 - "Meanwhile protein deficiency did not cause any significant reduction in immune response and completely removed activation of lysosomal hydrolases." 01/01/1989 - "[Activity of lysosomal hydrolases and renewal of proteins in the rat liver, spleen, and thymus during antigenic stimulation and protein deficiency]" 01/01/1979 - "The significance of activator proteins for the proper interaction of lipid substrates and water-soluble hydrolases is illustrated by the fatal glycolipid storage resulting from an activator protein deficiency in the AB variant of GM2-gangliosidosis. " Order ALL the reference details at left...
4.	Lymphoma (Lymphomas) 01/12/1980 - "As far as T-lymphomas are concerned, three hydrolases namely acid phosphates e, acid esterase and B-glucuronidase give the same good results. " Order ALL the reference details at left...
5.	Duodenal Ulcer (Curling's Ulcer) 01/01/2002 - "When studying the state of metabolism of the main substance of the connective tissue (glycosaminoglycan (GAG) and one of gag-hydrolases) in case of stomach and duodenal ulcers in patients under in-patient clinic conditions, it was shown that the amount of GAG in the urine approximately doubles in both groups in the state of exacerbation, and the given index reduces to the norm in the state of remission with a insignificant fluctuation of the b-glucuronidase level in the blood serum." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Glucuronidase
2.	Enzymes
3.	Acetylesterase
4.	Neuraminidase (Sialidase)
5.	Phosphates
6.	Sucrase (Sucrose alpha-D-Glucohydrolase)
7.	Isoproterenol (Isoprenaline)
8.	Oligo-1,6-Glucosidase (Isomaltase)
9.	Proteins (Proteins, Gene)
10.	Acid Phosphatase

Related Therapies and Procedures

1.	Homologous Transplantation (Allograft)
2.	Kidney Transplantation
3.	Bone Marrow Transplantation (Transplantation, Bone Marrow)
4.	Vagotomy
5.	Surgical Instruments (Clip)

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