|1.||Knudsen, Gitte M: 5 articles (03/2012 - 04/2007)|
|2.||Bauer, Andreas: 3 articles (12/2012 - 12/2005)|
|3.||Frokjaer, Vibe G: 3 articles (03/2012 - 09/2008)|
|4.||Svarer, Claus: 3 articles (02/2011 - 04/2007)|
|5.||Matusch, Andreas: 2 articles (12/2012 - 03/2009)|
|6.||Kalbitzer, Jan: 2 articles (03/2012 - 02/2011)|
|7.||Baaré, William F C: 2 articles (03/2012 - 02/2011)|
|8.||Erritzoe, David: 2 articles (02/2011 - 09/2008)|
|9.||Pinborg, Lars H: 2 articles (02/2011 - 04/2007)|
|10.||Lublin, Henrik: 2 articles (02/2011 - 09/2008)|
|1.||Schizophrenia (Dementia Praecox)
09/01/2008 - "Fifteen neuroleptic-naive patients diagnosed with schizophrenia (age 27.5+/-4.5 years), 11 men and 4 women, and 15 healthy control subjects matched for age (28.5+/-5.7 years) and gender underwent a 40 min positron emission tomography (PET) study using the 5-HT(2A) antagonist, [(18)F]altanserin, as a radioligand. "
12/01/2005 - "We used [18F] altanserin and positron emission tomography (PET) in a pilot study of 6 individuals suspected to be at elevated risk for schizophrenia and seven age-matched controls to test the hypothesis that regional 5-HT(2A)R binding is altered in the prodromal stages of schizophrenia. "
02/01/2011 - "Here, we measured serotonin2A receptor occupancy with [(18)F]altanserin PET in 15 first-episode antipsychotic-naïve schizophrenia patients before and after 6 months of quetiapine treatment. "
02/01/2000 - "[18F]altanserin has been used to label serotonin 5-HT2A receptors, which are believed to be important in the pathophysiology of schizophrenia and depression. "
06/01/2004 - "To avoid the confounding effects of malnutrition, we studied 10 women recovered from bulimia-type AN (REC AN-BN, > 1 year normal weight, regular menstrual cycles, no binging, or purging) compared with 16 healthy control women (CW) using PET imaging and a specific 5-HT(2A) receptor antagonist, [18F]altanserin. "
11/01/2002 - "This study applied positron emission tomography (PET) to investigate the brain serotonin 2A (5HT2A) receptor, which could contribute to disturbances of appetite and behavior in AN. To avoid the confounding effects of malnutrition, we studied 16 women recovered from AN (REC AN, >1 year normal weight, regular menstrual cycles, no bingeing or purging) compared with 23 healthy control women (CW) using [18F]altanserin, a specific 5-HT2A receptor antagonist on PET imaging. "
|3.||Alzheimer Disease (Alzheimer's Disease)
12/01/1999 - "No significant abnormalities in [18F]altanserin binding (binding potential) were observed in the patients with late-life depression, and no effect of depression on binding potential was present within the Alzheimer's disease group. "
12/01/1999 - "PET was performed by using [18F]altanserin to evaluate 5-HT2A receptor binding in 11 elderly patients with depression (four men, seven women; mean age = 65.0 years, SD = 5.5); nine Alzheimer's disease patients, including three with concurrent depression (two men, seven women; mean age = 69.7 years, SD = 5.0); and 10 age-matched healthy subjects (four men, six women; mean age = 69.8 years, SD = 5.0). "
03/01/2012 - "Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study."
|4.||Depressive Disorder (Melancholia)
|5.||Major Depressive Disorder (Major Depressive Disorders)
02/01/2004 - "We conducted a quantitative 5-HT(2A) receptor binding study using positron emission tomography and [(18)F]altanserin of four regions hypothesized to have altered levels of 5-HT(2A) receptors in major depressive disorder. "
02/01/2004 - "Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: in vivo measurement with [18F]altanserin positron emission tomography."
|1.||5-HT2A Serotonin Receptor (5 HT2A Receptor)
|2.||Serotonin (5 Hydroxytryptamine)
|3.||3- amino- 4- (2- dimethylaminomethylphenylsulfanyl)benzonitrile
|4.||amphetaminil (AN 1)
|7.||Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)
|8.||Pargyline (Pargyline Hydrochloride)