Malnutrition

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7103 relevant articles (166 outcomes, 606 trials/studies) found for this Disease

Description: An imbalanced nutritional status resulted from insufficient intake of nutrients to meet normal physiological requirement.

Also Known As:

Nutritional Deficiencies; Nutritional Deficiency; Undernutrition

Relationship Network

Disease Context: Research Results

Nutritional and Metabolic Diseases

Nutrition Disorders: 189

Malnutrition: 7103

Starvation: 10446

Deficiency Diseases: 383

Fetal Nutrition Disorders: 41

Refeeding Syndrome: 37

Related Diseases

1.	Infection
2.	Diarrhea
3.	Neoplasms (Cancer)
4.	Deglutition Disorders (Dysphagia)
5.	Inflammation

Experts

1.	Forrester, Terrence: 8 articles (10/2007 - 09/2002)
2.	Badaloo, Asha: 7 articles (10/2007 - 09/2002)
3.	Reid, Marvin: 7 articles (10/2007 - 09/2002)
4.	Jahoor, Farook: 6 articles (10/2007 - 09/2002)
5.	Lindholm, Bengt: 6 articles (01/2006 - 01/2002)
6.	Galler, Janina R: 6 articles (12/2003 - 06/2002)
7.	Sezer, Siren: 5 articles (07/2008 - 07/2002)
8.	Haberal, Mehmet: 5 articles (07/2008 - 07/2002)
9.	Selgas, Rafael: 4 articles (07/2008 - 01/2003)
10.	Mendes-Ribeiro, Antônio C: 4 articles (04/2008 - 06/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Malnutrition:

1.	Vitamin A (Retinol)FDA Link 09/01/2003 - "Fortified complementary foods could be effective in preventing and controlling vitamin A and other common nutritional deficiencies in young children. " 07/01/1999 - "We hypothesized that weekly low-dose vitamin A supplementation would prevent respiratory and diarrheal disease morbidity and that malnutrition might influence the efficacy of vitamin A supplementation. " 09/01/1992 - "We conducted a follow-up study among 220 Senegalese children aged 2-7 years suffering from moderate undernutrition to determine the efficacy of vitamin A treatment on their vitamin A status assessed by biochemical and cytological (impression cytology with transfer) methods. " 01/01/2007 - "This paper reported results from a study of vitamin A status and malnutrition of the minority ethnic group of Karen hill tribe children aged 1-6 years in the north of Thailand. " 10/01/1998 - "Studies in the literature from 1941 have reported that nutritional deficiency of vitamin A during pregnancy could lead to CDH, associated or not with other malformations in young rats. " Order ALL the reference details at left...
2.	Insulin-Like Growth Factor I (IGF-1)IBA 07/01/1994 - "When their appropriate-for-gestational-age littermates were pair-fed this intake, there were no significant differences in plasma or hepatic concentrations of IGF-I. Thus, under conditions of controlled food intake, prenatal undernutrition does not affect the postnatal expression of IGF-I. However, when appropriate-for-gestational-age piglets were fed to repletion at 6-h intervals over the 12 d, they had a significantly greater hepatic IGF-I concentration (p < 0.002) and food intake (p < 0.001) than the small-for-gestational-age piglets, indicating a critical role for food intake regulation in catch-up growth. " 03/01/1999 - "When the effects of undernutrition were examined in specific brain regions of each group, the same pattern was observed, and IGF-I was found to be more effective in preserving the growth of the regions with the highest transgene expression (cerebral cortex, hippocampus, and diencephalon). " 09/01/2009 - "Early studies emphasized the role of malnutrition in suppression of IGF-I production. " 08/01/2003 - "This study evaluated the impact of varying degrees of prolonged malnutrition on the local insulin-like growth factor-I (IGF-I) system in the costal diaphragm muscle. " 01/01/1997 - "The aim of the study was to determine if a decrease in serum insulin-like growth factor I (Igf-I) levels under marginal malnutrition is responsible for the lower physical performance of girls of a low socio-economic status (LSES). " Order ALL the reference details at left...
3.	MicronutrientsIBA 10/01/2000 - "Our data suggest that tomatoes may be beneficial for child health but also emphasize the general importance of food-based approaches to the prevention of micronutrient malnutrition and protection of the health of children in developing countries." 03/01/2002 - "The final permanent solution to micronutrient malnutrition in developing countries is a substantial improvement in dietary quality--higher consumption of pulses, fruits, vegetables, fish and animal products that the poor already desire but cannot presently afford. " 07/01/2008 - "CONCLUSION: In CD and UC, selected micronutrient deficits and loss of BCM and muscle strength are frequent in remission and cannot be detected by standard malnutrition screening." 06/25/2009 - "RESULTS: Nationwide surveys, as well as smaller studies have documented high rates of stunting, malnutrition and deficiency of micronutrients among South African children. " 09/01/2003 - "I: a FOODlet-based multiple-micronutrient intervention in 6- to 12-month-old infants at high risk of micronutrient malnutrition in four contrasting populations: description of a multicenter field trial." Order ALL the reference details at left...
4.	Glucose (Dextrose)FDA LinkGeneric 05/01/2008 - "This study investigated whether undernutrition (UN) during late fetal life can programme the subsequent adult life adaptation of glucose homeostasis and metabolism during pregnancy and lactation. " 01/01/2005 - "Several clinical studies have shown that amino-acid solution improves various nutritional parameters in patients with malnutrition and is more biocompatible than standard glucose solution. " 04/01/2009 - "We conclude that maternal undernutrition around the time of conception results in impaired glucose tolerance in postpubertal offspring." 04/01/2009 - "We determined the effect of maternal periconceptional undernutrition in sheep on glucose tolerance in the offspring before and after puberty. " 04/01/2009 - "Periconceptional undernutrition of ewes impairs glucose tolerance in their adult offspring." Order ALL the reference details at left...
5.	Amino Acids FDA Link 06/02/2008 - "The availability of amino acids is a key factor for the overall metabolism of mammals and exogenous supplements of amino acid mixtures (AAm) could be a valid therapeutic strategy to improve quality of life, avoiding malnutrition and muscle wasting in the elderly. " 04/01/2008 - "Baggs ewes adapt to maternal undernutrition and maintain conceptus growth by maintaining fetal plasma concentrations of amino acids." 09/01/2007 - "The above conditions may create a state of temporary malnutrition of mammary epithelial cells, which forces the cells to the induction of autophagy, as a mechanism for stabilizing intracellular supplies of energy and amino acids, especially during the enhanced activity of apoptogenic factors." 08/01/2007 - "Protein malnutrition reduces concentrations of most amino acids in plasma. " 06/01/2006 - "With such early malnutrition, limited amino acids would be partitioned between two physiological objectives, successful reproduction vs. continued growth. " Order ALL the reference details at left...
6.	VitaminsIBA 09/01/2006 - "CONCLUSION: Treatment with B-vitamin supplementation may be beneficial for the treatment of patients with AN, in cases in which the disorder develops at an early age before brain maturation (i.e., childhood-onset cases), along with an enduring course of malnutrition." 12/01/1984 - "The results of this pilot study indicated that a long-term intervention trial was feasible in Linxian and that the RDA dose level of vitamins was effective in ameliorating certain nutritional deficiencies prevalent in the study population." 07/01/2008 - "OBJECTIVE: This study aims to measure (1) the frequency of Cu, Fe, and Zn deficiencies in children with acute malnutrition on day 1 and after 15- and 30-day treatments with F100 plus vitamins/minerals mix, and (2) anthropometric recovery after 30 d feeding ad libitum. " 11/01/1996 - "Vitamin B-6 malnutrition among elderly Europeans: the SENECA study." 12/01/1984 - "The study establishes the low nutritional status in vitamins of the population in Linxian and provides the background for further studies on the effects of nutritional deficiency on carcinogenesis." Order ALL the reference details at left...
7.	Prealbumin (Transthyretin)IBA 08/01/1986 - "Statistically significant reduction in prealbumin, C3, C4 and TC were found only in group I. The observations suggest a relationship between immunonutritional status and preparation for large-bowel surgery, reproducing a state of acute malnutrition." 11/01/2003 - "It is useful to incorporate prealbumin and BIA parameters in the regular assessment of PD patients, whose survival may be improved by better management of malnutrition and overall health status." 07/01/2009 - "In conclusion, assessment of prealbumin CRII is useful for early prediction of improved nutritional status in patients with malnutrition." 03/01/2008 - "Prealbumin levels were significantly lower in patients with chronic malnutrition than the patients without malnutrition. " 12/01/2006 - "Serum prealbumin: Is it a marker of nutritional status or of risk of malnutrition?" Order ALL the reference details at left...
8.	IronIBA 01/11/2008 - "Consumption of iron ameliorates iron deficiency, the most prevalent nutritional deficiency in the world, affecting approximately 2 billion persons. " 02/04/2009 - "This study demonstrated that malnutrition, especially iron deficiency, might act as a confounding factor in EDC-induced oxidative stress. " 01/01/2009 - "The reduction in albumin and TBPA associated with the iron deficiency but in the absence of any sign of malnutrition (W/H > 96%) or inflammatory risk (PINI < 2) in either study group shows that iron may play a dominant role during protein synthesis. " 01/01/2002 - "First, carefully designed random assignment studies in the laboratory and field provide compelling evidence that nutritional deficiency - particularly iron deficiency - reduces work capacity and, in some cases, work output. " 01/01/2002 - "RESULTS: The study revealed that due to lack of awareness and poor socio economic status the daily wages labourers are more prone to malnutrition and iron deficiency anaemia. " Order ALL the reference details at left...
9.	Anti-Bacterial Agents (Antibiotics)IBA 11/01/1982 - " The minipill is as effective as other formulations except in cases of chronic malnutrition or concomitant use of antibiotics or anticonvulsives. " 03/01/1990 - "Further studies are required on the effects of malnutrition on drug pharmacokinetics, especially in relation to antibiotics. " 06/01/1985 - "The studies were carried out on nourished and malnourished rats and extended to a recovery period induced by antibiotics to determine the effects of malnutrition on the establishment and repair of disaccharidase deficiencies caused by bacterial overgrowth. " 01/01/1975 - "A double-blind trial in the use of antibiotics in this condition is advocated to determine whether it is possible to break the diarrhoea-malabsorption-malnutrition cycle. " 03/01/2008 - "BACKGROUND: Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). " Order ALL the reference details at left...
10.	CreatinineIBA 05/01/2004 - "In the dialysis population, somatic protein mass, a useful marker of protein malnutrition, is estimated using the creatinine index (CI), lean body mass (LBM) or both, but the clinical usefulness of these indices remains uncertain. " 07/01/2003 - "However, malnutrition appeared significantly more frequently in females, and malnourished patients had significantly higher serum creatinine levels. " 12/01/2000 - "The mean age of the patients was 52 +/- 12 years, and creatinine clearance was 9 +/- 3 mL/min. Malnutrition was seen in 53 patients (48%). " 02/01/2000 - "Malnutrition was defined by the presence of at least one of these criteria: body mass index &lE 18.5 kg/m(2); height-creatinine index << 70%; or albumin level << 3. 5 g/dl. " 03/01/1999 - "Access for long-term dialysis should be created when the serum creatinine value increases above 4.0 mg/dL or the glomerular filtration rate declines below 20 mL/min. Nutritional status must be closely monitored in order to avoid protein malnutrition and to initiate dialysis before the patient's nutritional status has deteriorated. " Order ALL the reference details at left...

Therapies and Procedures

1.	Nutritional Support (Artificial Feeding) 11/01/1986 - "Nutritional assessment has three main aims: to define the type and severity of malnutrition; to identify high risk patients; to monitor the efficacy of nutritional support. " 12/09/1999 - "Provision of nutritional support has been shown to improve patient outcome in those at risk of malnutrition; therefore, the detection and treatment of malnutrition is paramount. " 10/01/2009 - "BACKGROUND & AIMS: We conducted a multicentre study to assess nutritional risk at hospital admission, hospital-associated iatrogenic malnutrition and the status of nutritional support in Turkish hospitals. " 10/01/2004 - "The objective of the present study was to assess the cost of malnutrition and related comorbidities among elderly patients living in the community and to determine the impact of nutritional support practice on these outcomes. " 03/01/1996 - "While long term studies are required to determine if nutritional support will prevent stunting, these results underscore its central role in preventing nutritional deficiencies and in promoting normal growth in thalassaemic children." Order ALL the reference details at left...
2.	Enteral Nutrition (Feeding, Tube) 10/01/1998 - "In patients with severe malnutrition significant improvement can be achieved by enteral feeding." 02/22/1995 - "Cyclic enteral nutrition appears to be a well-tolerated and effective treatment of undernutrition in older malnourished ambulatory patients, although their response to CyEN was somewhat less than in younger patients." 01/01/1989 - "Therefore, we think that the administration of enteral nutrition in this kind of patient is very useful and is indeed necessary to avoid energy-protein malnutrition during the postoperative period. " 02/01/2008 - "A pilot trial of proactive enteral feeding for patients at high risk of malnutrition has commenced. " 07/01/2009 - "Further questions were included concerning knowledge of recent guidelines on enteral nutrition (EN) in LC, use of an adequate EN and estimated prevalence of malnutrition. " Order ALL the reference details at left...
3.	Parenteral Nutrition 03/01/2007 - "Parenteral nutrition has been shown to improve clinical outcome in patients with malnutrition and intestinal tract dysfunction. " 09/28/2005 - "CONCLUSION: Perioperative parenteral nutrition possibly ameliorates the humoral immunity, reverses malnutrition, and facilitates rehabilitation." 08/01/2009 - "Several studies have demonstrated that 7-10 days of preoperative parenteral nutrition improves postoperative outcome in patients with severe undernutrition who cannot be adequately orally or enterally fed. " 07/01/2008 - "The objective of this study is to examine the prevalence of malnutrition and evaluate the nutrition status and clinical outcome in hospitalized patients aged 65 years and older receiving enteral-parenteral nutrition. " 08/01/1998 - "The aim of this study was to assess the impact of prolonged use of intradialysis parenteral nutrition (IDPN) as a strategy for malnutrition in elderly haemodialysis patients. " Order ALL the reference details at left...
4.	Fluid Therapy (Oral Rehydration Therapy) 04/01/2006 - "Improved knowledge of oral rehydration therapy, feeding during episodes to prevent further malnutrition, prolonged breastfeeding, and the keeping of livestock in corralled areas of the home are advocated." 01/01/1995 - " Use of oral rehydration therapy is limited, especially in Senegal, even though diarrheal disease is a major cause of death in young children, while chronic undernutrition affects more than 20% of Senegalese children and one in three in Burkina Faso. " 09/01/1990 - "Treatment is non-specific and includes the use of oral rehydration therapy, especially in developing countries where malnutrition is common. " 07/01/2003 - "The patient presented progressive intolerance to oral feeding and nutritional supplements, accompanied by severe malnutrition, requiring parenteral nutrition (PN), endovenous fluid therapy and requiring a second surgical intervention due to persistence of the occlusive condition, with resection of 70 cm of the terminal ileum with ileum-colon anastomosis. " 01/01/1985 - "This report of results obtained at the Center for Nutritional Rehabilitation and Oral Rehydration in Senegal suggests that simple techniques can be extremely effective in the treatment of diarrhea and severe malnutrition. " Order ALL the reference details at left...
5.	Gastrostomy 04/01/2000 - "Use of supplemental gastrostomy tube feeds has improved calorie-protein malnutrition. " 08/01/2009 - "OBJECTIVE: To determine whether gastrostomy placement for nutritional therapy alters the natural history of growth failure and undernutrition in RTT. " 06/02/2008 - "Percutaneous endoscopic gastrostomy (PEG) is a well-established method to treat malnutrition. " 07/01/2006 - "Consequently, percutaneous endoscopic gastrostomy may be needed for the correction of malnutrition. " 03/01/2006 - "AIM: Percutaneous endoscopic gastrostomy (PEG) is an accepted procedure for patients at risk of malnutrition, but it requires an invasive procedure and many complications can occur. " Order ALL the reference details at left...

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