|1.||Surh, Young-Joon: 2 articles (01/2002 - 01/2002)|
|2.||Chun, Kyung-Soo: 2 articles (01/2002 - 01/2002)|
|3.||Xu, Peng: 1 article (09/2013)|
|4.||Wang, Sheng: 1 article (09/2013)|
|5.||Chen, Feng: 1 article (09/2013)|
|6.||Tan, Yinfeng: 1 article (09/2013)|
|7.||Duan, Jinao: 1 article (09/2013)|
|8.||Li, Yonghui: 1 article (09/2013)|
|9.||Zhang, Junqing: 1 article (09/2013)|
|10.||Wang, Hui-Chuan: 1 article (01/2013)|
01/01/2002 - "In parallel with suppression of tumor promotion, topically applied yakuchinone A and B markedly inhibited TPA-induced epidermal ODC activity and ODC mRNA expression. "
07/16/1999 - "In the present work, we have evaluated the anti-tumor promoting potential of yakuchinone A (1-[4'-hydroxy-3'-methoxyphenyl]-7-phenyl-3-heptanone) and yakuchinone B (1-[4'-hydroxy-3'-methoxyphenyl]-7-phenylhept-1-en-3-one), major pungent ingredients of A. "
04/01/2009 - "oxyphylla and their structures were identified as: (9E)-humulene-2, 3; 6, 7-diepoxide (1), 3(12), 7(13), 9(E)-humulatriene-2, 6-diol (2), (-)-oplopanone (3), yakuchinone A (4), yakuchinone B (5), tectochrysin (6), isovanillin (7), (2E, 4E)-6-hydroxy-2, 6-dimethylhepta-2, 4-dienal (8), and the cytotoxicities of compounds 1, 3-5 on cancer cell lines, A549, HT-29 and SGC-7901, were also investigated. "
01/01/2002 - "In the present work, we show that both yakuchinone A and yakuchinone B inhibit the expression of cyclooxygenase-2 (COX-2) and of inducible nitric oxide synthase (iNOS) as well as the expression of tumor necrosis factor (TNF)-alpha mRNA in mouse skin treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). "
|2.||Skin Neoplasms (Skin Cancer)
01/01/2013 - "Yakuchinone A induces apoptosis and inhibits cell proliferation in skin cancer cells. "
01/01/2013 - "The inhibition of cell growth by yakuchinone A is more significant for non-melanoma skin cancer (NMSC) cells than for melanoma (A375 and B16) and noncancerous (HaCaT and BNLCL2) cells. "
01/01/2013 - "Antioxidant and antitumor characteristics of yakuchinone A in skin cancer cells as well as novel mechanisms for the inhibition of adipocyte differentiation, cestocidal activities against Hymenolepis nana adults, and nematocidal activities against Anisakis simplex larvae are investigated. "
|3.||Melanoma (Melanoma, Malignant)
07/16/1999 - "Yakuchinone A [1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone] and yakuchinone B [1-(4'-hydroxy-3'-methoxyphenyl)-7-phenylhept-1-en-3-one] present in Alpinia oxyphylla Miquel (Zingiberaceae) have inhibitory effects on phorbol ester-induced inflammation and skin carcinogenesis in mice, and oxidative stress in vitro. "
|2.||Messenger RNA (mRNA)
|4.||Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
|5.||Cyclooxygenase 2 (Cyclooxygenase-2)
|6.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)