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Efficacy of intravenous propafenone in termination of atrial flutter by overdrive transesophageal pacing previously ineffective.

Abstract
Fifty patients with symptomatic type I atrial flutter in whom termination of the arrhythmia with transesophageal stimulation was unsuccessful were randomized to undergo a repeat procedure after intravenous propafenone (n = 25) or placebo (n = 25). Immediate sinus rhythm recovery rate was 36% in the propafenone group and 4% in the placebo group (p = 0.005), indicating that intravenous propafenone increases the rate of successful transesophageal stimulation and can be used when a first attempt at conversion is ineffective.
AuthorsD D'Este, E Bertaglia, R Mantovan, A Zanocco, M Franceschi, P Pascotto
JournalThe American journal of cardiology (Am J Cardiol) Vol. 79 Issue 4 Pg. 500-2 (Feb 15 1997) ISSN: 0002-9149 [Print] United States
PMID9052359 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Anti-Arrhythmia Agents
  • Propafenone
Topics
  • Aged
  • Anti-Arrhythmia Agents (therapeutic use)
  • Atrial Flutter (therapy)
  • Electric Countershock (methods)
  • Heart Rate
  • Humans
  • Middle Aged
  • Propafenone (therapeutic use)
  • Prospective Studies
  • Treatment Outcome

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