[Drug treatment in vulvar lichen sclerosus].

Abstract

This study was made in the Oncologic Gynecology's surgery of the Department of Obstetrics and Gynecology of the University of Naples. We evaluated the efficacy of local therapy with testosterone and progesterone in Vulvar Lichen Sclerosus. We treated 65 women suffering from Vulvar Lichen Sclerosus. In the group of 38 women treated with testosterone, we observed a complete response in 26 cases (68%). In the group of 27 women treated with progesterone we observed a complete response in 18 cases (66.6%). This demonstrates the efficacy of local therapy with testosterone and Progesterone in Vulvar Lichen Sclerosus. The authors believe that medical treatment with topical testosterone and progesterone represents an effective alternative to invasive methods for the care of Vulvar Lichen Sclerosus.

• Authors: R Zarcone, G Vicinanza, P Bellini, A Cardone
• Journal: Minerva ginecologica (Minerva Ginecol) Vol. 48 Issue 10 Pg. 441-4 (Oct 1996) ISSN: 0026-4784 [Print] Italy
• Vernacular Title: Il trattamento medico nel lichen scleroso vulvare.
• PMID: 9005369 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Testosterone
• Progesterone

Topics

• Administration, Topical
• Adult
• Aged
• Aged, 80 and over
• Female
• Humans
• Lichen Sclerosus et Atrophicus (drug therapy)
• Middle Aged
• Progesterone (administration & dosage)
• Testosterone (administration & dosage)
• Time Factors
• Vulvar Diseases (drug therapy)