The potential role and mechanisms of FeLV vaccine-induced neoplasms.

Abstract

Vaccine-induced sarcomas are reported to occur in 1 in 10,000 or less cats vaccinated with feline leukemia virus (FeLV) vaccines. The potential of local vaccine site adjuvant-associated inflammation plays in the pathogenesis of these tumors is probably significant. However, it is believed that the feline leukemia antigens contained within these vaccines also play an important role in malignant transformation.

• Authors: D W Macy
• Journal: Seminars in veterinary medicine and surgery (small animal) (Semin Vet Med Surg Small Anim) Vol. 10 Issue 4 Pg. 234-7 (Nov 1995) ISSN: 0882-0511 [Print] United States
• PMID: 8820597 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S., Review)

Chemical References

• Viral Vaccines

Topics

• Animals
• Cat Diseases (etiology)
• Cats
• Fibrosarcoma (etiology, veterinary)
• Leukemia Virus, Feline (immunology)
• Neoplasms (etiology, veterinary)
• Viral Vaccines (adverse effects, pharmacology)