[Phospholipid composition of rabbit liver mitochondria in moderately severe tracheal stenosis].

Abstract

A decrease in phosphatidyl cholines by 32.5%, phosphatidyl ethanolamines by 32.9%, cardiolipins by 28.8% and sphingomyelins by 48% as well as increase in concentration of phosphatidyl serine 4.2-fold, phosphatidyl inositol 4.1-fold, phosphatidic acid 10.3-fold and lysophosphatidyl cholines 2.7-fold were detected in liver mitochondria of rabbits with moderate tracheal stenosis. At the same time, the phosphatidyl choline/phosphatidyl ethanolamine ratio which is of importance in stabilizing membrane structures, was increased 1.5-fold. The ratio of diacyl forms of phospholipids and their lyso derivatives was also altered in stenosis of trachea: the phosphatidyl choline/lysophosphatidyl choline ratio was increased 4-fold.

• Authors: K T Almatov, M Obidkhonov
• Journal: Voprosy meditsinskoi khimii (Vopr Med Khim) 1993 Mar-Apr Vol. 39 Issue 2 Pg. 57-8 ISSN: 0042-8809 [Print] Russia (Federation)
• Vernacular Title: Fosfolipidnyĭ sostav mitokhondriĭ pecheni krolikov pri stenoze trakhei sredneĭ tiazhesti.
• PMID: 8511893 (Publication Type: English Abstract, Journal Article)

Chemical References

• Phospholipids

Topics

• Animals
• Male
• Mitochondria, Liver (metabolism)
• Phospholipids (metabolism)
• Rabbits
• Tracheal Stenosis (metabolism)