[Efficacy of and tolerance to a new NSAID in the treatment of arthrosis: droxicam. Randomized study versus tenoxicam].

Abstract

A four-week open study was carried out to evaluate the efficacy and tolerability of droxicam, a new NSAID, in the treatment of painful osteoarthritis (OA). The results were compared with those obtained treating a similar group of patients with tenoxicam, at the same dosage of 20 mg/day, orally administered. The study showed that both drugs are effective in treating OA, with a mild predominance of droxicam in decreasing pain, functional limitation and chronic inability score. Tolerability was excellent or good in over 70% of patients and only one subject of each group was dropped out for severe side-effects. According to the Authors droxicam has shown to be an effective analgesic and anti-inflammatory agent as judged by its efficacy on pain relief and joint mobility in OA.

• Authors: M Chevallard, C Venegoni, B Colombo
• Journal: Minerva medica (Minerva Med) Vol. 84 Issue 3 Pg. 125-30 (Mar 1993) ISSN: 0026-4806 [Print] Italy
• Vernacular Title: Efficacia e tollerabilità di un nuovo FANS nella terapia dell'artrosi: il droxicam. Studio randomizzato versus tenoxicam.
• PMID: 8492964 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Pyridines
• Piroxicam
• droxicam
• tenoxicam

Topics

• Adult
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Osteoarthritis (drug therapy)
• Piroxicam (analogs & derivatives, therapeutic use)
• Pyridines (therapeutic use)