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Diffuse neurofibrillary tangles with calcification: a new presenile dementia.

Abstract
The term "diffuse neurofibrillary tangles with calcification" (DNTC) is proposed for a new form of presenile dementia. It is characterised by slowly progressive cortical dementia in the presenium, localised temporal or temporofrontal lobar atrophy, numerous neurofibrillary tangles widespread in the cerebral cortex, and pronounced calcareous deposits; 16 cases of DNTC, have been reported.
AuthorsK Kosaka
JournalJournal of neurology, neurosurgery, and psychiatry (J Neurol Neurosurg Psychiatry) Vol. 57 Issue 5 Pg. 594-6 (May 1994) ISSN: 0022-3050 [Print] England
PMID8201331 (Publication Type: Case Reports, Journal Article)
Topics
  • Aged
  • Brain (diagnostic imaging, pathology)
  • Calcinosis (diagnostic imaging, pathology)
  • Dementia (diagnostic imaging, pathology)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurofibrillary Tangles (pathology)
  • Tomography, X-Ray Computed

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