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Febarbamate-induced pulmonary eosinophilia: a case report.

Abstract
Subacute pulmonary hypersensitivity to febarbamate is reported, manifested by peripheral eosinophilia, skin rash and pulmonary bilateral infiltrates. Bronchoalveolar lavage showed an increased eosinophil count, and transbronchial biopsy an intraalveolar and interstitial eosinophil infiltration. The reaction cleared on cessation of the drug, and a rechallenge test with febarbamate induced peripheral eosinophilia and skin rash.
AuthorsJ M Gali, J L Vilanova, M Mayos, R Cornudella, P de las Heras, J M Rodriguez Arias
JournalRespiration; international review of thoracic diseases (Respiration) Vol. 49 Issue 3 Pg. 231-4 ( 1986) ISSN: 0025-7931 [Print] Switzerland
PMID3961285 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Barbiturates
  • febarbamate
Topics
  • Adult
  • Barbiturates (adverse effects)
  • Drug Hypersensitivity (diagnosis, etiology)
  • Humans
  • Male
  • Pulmonary Eosinophilia (chemically induced, diagnosis)

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