Brucella osteomyelitis of a closed femur fracture.

Abstract

A 19-year-old man incurred a closed femoral fracture complicated by hematogenous dissemination of Brucella osteomyelitis. Repeated limited incision and drainage were ineffective in eradicating infection. Wide debridement, delayed wound closure, and vigorous antimicrobial therapy with streptomycin and tetracycline, along with cephalosporin for secondary staphylococcal infection, were necessary measures before the infection was eradicated. A constant awareness of brucella musculoskeletal infection is advisable when caring for patients frequently exposed to all kinds of livestock, including domesticated and wild animals.

• Authors: M A Abrahams, C M Tylkowski
• Journal: Clinical orthopaedics and related research (Clin Orthop Relat Res) Issue 195 Pg. 194-6 (May 1985) ISSN: 0009-921X [Print] United States
• PMID: 3919984 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cephalosporins
• Tetracycline
• Streptomycin

Topics

• Adult
• Brucella abortus
• Brucellosis (etiology, therapy)
• Cephalosporins (therapeutic use)
• Combined Modality Therapy
• Debridement
• Drainage
• Femoral Fractures (complications)
• Fractures, Closed (complications)
• Humans
• Male
• Osteomyelitis (etiology, therapy)
• Staphylococcal Infections (etiology, therapy)
• Streptomycin (therapeutic use)
• Tetracycline (therapeutic use)
• Time Factors
• Wound Infection (etiology, therapy)