Staphylococcal Infections

02/18/1999 - "Since the emergence of methicillin-resistant Staphylococcus aureus, the glycopeptide vancomycin has been the only uniformly effective treatment for staphylococcal infections. "
11/01/1982 - "Vancomycin hydrochloride therapy was initiated in anticipation of a staphylococcal infection, and continued as the patient's clinical course improved. "
11/01/1981 - "Vancomycin is an effective and safe agent for treatment of staphylococcal infections in pediatric patients."
11/01/1981 - "Pharmacology and efficacy of vancomycin for staphylococcal infections in children."
11/01/1981 - "The current renewal of interest in vancomycin for treatment of severe staphylococcal infections stems primarily from the efficacy of this drug against methicillin-resistant pathogens and its utility in a number of unique clinical situations. "

02/01/2004 - "This assay of bacterial replication was used to evaluate the efficacy of antibiotics which are commonly used to treat staphylococcal infections. "
03/01/1975 - "These studies suggest that the 1/8 level of bactericidal activity should be attained in the serum one hour after the administration of the antibiotics to allow optimal results in staphylococcal infections."
01/01/1971 - "Study of bactericidal and bacteriostatic antibiotics in experimentally diabetic and senescent mice, in cases of lethal staphylococcal infection."
02/20/1969 - "[Effect of antibiotics on pathogenic staphylococcal infection tissue culture study]."
09/01/2015 - "A hallmark of staphylococcal infections is their frequent recurrence, even when treated with antibiotics and surgical intervention, which demonstrates the bacterium's ability to manipulate innate and adaptive immune responses. "

11/01/2004 - "This study suggests that an oral regimen containing a fluoroquinolone plus rifampicin may be effective for treating staphylococcal infections, allowing earlier discharge from the hospital."
07/01/1983 - "Thus, there is firm in vitro and in vivo support for studies of the clinical efficacy of rifampin for staphylococcal infections."
05/20/1998 - "To evaluate the clinical efficacy of a rifampin combination in staphylococcal infections associated with stable orthopedic devices. "
07/01/2012 - "The role of rifampin against device-associated staphylococcal infection has been evaluated in an animal model, in observational studies and in a controlled trial. "
01/01/2015 - "It is important to use an antibiotic combination including rifampin in staphylococcal infections."

06/01/2004 - "The introduction of penicillin in the 1940s greatly improved the prognosis for patients with severe staphylococcal infections. "
06/01/1962 - "[Renal and extrarenal clearance of penicillin from the blood plasma of rabbits in normal conditions and in experimental staphylococcal infection]."
04/01/1958 - "[The effect of functional condition of the central nervous system on the efficacy of penicillin therapy in experimental staphylococcal infections]."
07/01/1961 - "[1st trials of a new synthetic penicillin in the treatment of staphylococcal infections in children]."
10/01/2004 - "The authors do not recommend crystalline penicillin in the management of severe staphylococcal infections even in cases, where the isolated S. "

08/01/2005 - "A meta-analysis of studies performed in developed countries showed a trend of increasing risk for coagulase-negative staphylococcal infection. "
06/01/2004 - "A screened human polyclonal antibody and a humanized chimeric monoclonal antibody are both under investigation (in phase II-III clinical trials) for prevention of coagulase-negative staphylococcal infections in high-risk neonates. "
03/01/2003 - "A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units."
11/01/1994 - "Our data corroborate previous studies indicating risk factors and predictors of coagulase-negative staphylococcal infection."
03/01/2015 - "Challenges of diagnosing coagulase-negative staphylococcal infections result in conflicting definitions and inconsistent clinical practice. "

11/01/1993 - "Our results suggest that teicoplanin is highly effective and safe in neonatal staphylococcal infections."
11/01/2007 - "Previously published data suggest that a trough serum teicoplanin level of > or = 20 mg/l is predictive of improved outcomes in serious staphylococcal infection. "
04/01/1988 - "Poor efficacy of teicoplanin in treatment of deep-seated staphylococcal infections."
11/01/1993 - "In the present study 19 newborns (7 at term, 12 preterm) with proven staphylococcal infection were treated with teicoplanin, after a previous ineffective antibiotic treatment (amikacin+oxacillin or third-generation cephalosporin). "
09/01/2004 - "We aimed to evaluate retrospectively the clinical and bacteriological efficacy and potential side-effects of teicoplanin treatment in neonates with proven staphylococcal infection. "

12/01/2009 - "When a staphylococcal infection is suspected but the resistance phenotype is not known, agents that are effective against methicillin-susceptible S. "
12/01/2004 - "Community-acquired staphylococcal infections may be treated with agents effective against methicillin-sensitive strains."
07/16/2014 - "Resistance to the most common antimicrobials tested for in published studies and important for the treatment of staphylococcal infections in dogs were assessed separately for methicillin resistant (MRSP) and methicillin susceptible (MSSP) isolates. "
08/01/2012 - "The increasing incidence and implications of staphylococcal infections, particularly meticillin-resistant staphylococcal infections, is leading to more interest in infection control in veterinary hospitals as a means to help reduce the impact of these significant pathogens. "
08/15/2008 - "Prior staphylococcal infection (methicillin-susceptible S. "

09/01/1958 - "The efficacy of erythromycin in the control and prevention of an endemic staphylococcal infection in a large private hospital nursery."
07/01/2005 - "These findings show that ethosomes are efficient carriers for erythromycin delivery to bacteria localized within the deep skin strata for eradication of staphylococcal infections."
12/01/1977 - "The staphylococcal infection rate in the units where erythromycin was used did not fall but the mortality rate from staphylococcal infection did."
12/01/1977 - "Erythromycin resistance in neonatal staphylococcal infection: a long-term survey."
06/23/1975 - "Letter: Erythromycin in staphylococcal infections."

08/01/2001 - "The results from this experimental model suggest that the oxazolidinone linezolid may be effective for the treatment of serious staphylococcal infections when resistance to other antimicrobials is present."
10/01/2003 - "Combination studies demonstrated that only the treatments that included linezolid produced no evidence of staphylococcal infection. "
08/01/2011 - "Timely detection and targeted prevention of further dissemination in both human and veterinary medicine is warranted for preserving the activity linezolid as an important antibiotic for treatment of staphylococcal infections."
06/01/2003 - "Safety assessments were conducted for 2,046 linezolid-treated patients and 2,001 comparator drug-treated patients from seven controlled clinical trials comparing the activities of linezolid and comparator drugs against nosocomial and community-acquired pneumonia, skin and skin structure infections, and methicillin-resistant staphylococcal infections. "
06/01/2011 - " study suggests that linezolid combinations with doxycycline may be synergistic in treating staphylococcal infections."

04/23/1977 - "These studies showed that 18-hour diffusion sensitivity tests indicate the clinical value of treatment with flucloxacillin for staphylococcal infections of moderate severity more correctly at 37 degrees C than at 30 degrees C."
07/01/2010 - "These data support current Australian recommendations for the use of flucloxacillin or a first-generation cephalosporin as initial treatment of non-life-threatening staphylococcal infections. "
08/01/1994 - "In addition, flucloxacillin (1-2 g every 4 h) could be added if there was clinical suspicion of staphylococcal infection. "
08/01/1993 - "In addition, flucloxacillin (1-2 g, every 4 h) could be added if there was clinical suspicion of staphylococcal infection (17 in each arm). "
01/01/1986 - "A total of twenty-nine children were admitted to the paediatric unit with confirmed or presumed staphylococcal infection and subsequently treated with the narrow spectrum antibiotic--flucloxacillin. "

10/01/2010 - "Patients with staphylococcal infection, elevated American Society of Anesthesiologists score, and purulence around the prosthesis were more likely to fail. "
02/01/2003 - "Staphylococcal infections are a common and severe complication after the implantation of a prosthesis. "
08/01/1988 - "One patient had the prosthesis removed more than one year postoperatively for late haematogenous staphylococcal infection and had a poor rating. "
12/16/1965 - "Staphylococcal infection of a Starr-Edwards prosthesis, with fatal obstruction of the mitral valve."
01/01/1998 - "Antibiotic therapy of deep-seated staphylococcal infections, especially when they are associated with foreign implants, such as orthopedic prostheses and permanently inserted catheters, is a difficult challenge. "

08/01/2008 - "To this aim, data from patients with implant staphylococcal infections (1998-2006) treated with debridement and implant retention were retrospectively reviewed. "
11/01/1997 - "Two unusual cases involving 2 patients with 3 hematogenously spread acute staphylococcal infections that occurred in musculotendinous compartments and required surgical debridement are reported. "
05/01/1999 - "aureus is prevalent in the community, methicillin resistance should be considered in any overwhelming staphylococcal infection not responding to conventional antibiotics despite adequate surgical debridement."
06/01/2007 - "There is growing evidence of the efficacy of treating early staphylococcal infections of prosthetic joints with surgical debridement and prosthesis retention, combined with oral antibiotic regimens that include rifampicin in combination with a fluoroquinolone. "
05/01/1985 - "Wide debridement, delayed wound closure, and vigorous antimicrobial therapy with streptomycin and tetracycline, along with cephalosporin for secondary staphylococcal infection, were necessary measures before the infection was eradicated. "

01/01/2014 - "PET/CT imaging with novel (68)Ga-DOTA-Siglec-9 tracer was able to detect inflammatory tissue response induced by catheter implantation and staphylococcal infections."
01/01/2010 - "Antibiotic-impregnated catheters were associated with a significant decrease in both overall and staphylococcal infection (p = 0.030 and p = 0.045, respectively). "
09/01/2001 - "Effect of preventing Staphylococcus aureus carriage on rates of peritoneal catheter-related staphylococcal infections. "
06/01/2001 - "The data reported indicate an important role of ica genes as a virulence marker in staphylococcal infections from intravenous catheters."
01/01/1998 - "Central venous catheters are often used for dialysis, and patients on dialysis often run into staphylococcal infections. "

07/01/1987 - "Chemotherapy has changed the clinical spectrum of staphylococci but has not eradicated serious staphylococcal infections. "
12/01/1986 - "The purpose of our study was to construct a tolerant mutant which would then serve as a reference strain and could also be used for testing the potential significance of antibiotic tolerance during chemotherapy of staphylococcal infections. "
12/01/2009 - "Clinicians should be aware that invasive staphylococcal infections are associated with biologic and disease modifying antirheumatic drug therapy, and these may present atypically and be rapidly progressive. "
01/01/2006 - "Due to high resistance, standard chemotherapy of biofilm-associated staphylococcal infections is ineffective and a number of alternative approaches to antimicrobial treatment have been proposed. "
12/10/1990 - "[Drug therapy of intractable methicillin-resistant staphylococcal infections]."

07/01/2007 - "Staphylococcal infections are a major cause of morbidity and mortality in patients on hemodialysis. "
12/01/1988 - "Staphylococcal infections in the hemodialysis unit: prevention using infection control principles."
07/01/1978 - "Staphylococcal infections in a hemodialysis unit."
08/01/2009 - "aureus infections in daily hemodialysis practice from a clinical viewpoint, starting from some key issues in the pathogenesis of staphylococcal infections."
01/01/1980 - "We conclude that 1 gm vancomycin every 7 days is an effective regimen for serious staphylococcal infections in chronic hemodialysis patients. "