Treatment of Cutaneous Rosai-Dorfman Disease with ALA-PDT Combined with Low-dose Oral Corticosteroids: A Case Report.

Abstract

Cutaneous Rosai-Dorfman Disease (CRDD), a rare form of Rosai-Dorfman Disease (RDD), lacks established treatment guidelines. In this case report, we detailed a successful case of CRDD management in a 50-year-old woman with facial lesions. Our treatment included 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and low-dose oral corticosteroids. Remarkable improvement was evident after six ALA-PDT courses, and a one-year follow-up confirmed sustained remission. This case highlights the potential of combining ALA-PDT with low-dose corticosteroids as a promising therapeutic strategy for CRDD. Further research is necessary to fully elucidate its mechanisms and effectiveness.

• Authors: Runke Zhou, Tingting Wang, Erlong Li, LiLi
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Pg. 103914 (Nov 30 2023) ISSN: 1873-1597 [Electronic] Netherlands
• PMID: 38042238 (Publication Type: Case Reports)
• Copyright: Copyright © 2023. Published by Elsevier B.V.