Transconjunctival XEN45 implantation for secondary open-angle glaucoma management in a pediatric patient with WAGR syndrome.

Abstract

Purpose:

To report a case of XEN45 gel stent implantation in a pediatric patient with WAGR syndrome as a successful surgical intervention in the management of multifactorial secondary open-angle glaucoma.

Observations:

A 6-year-old female with a history of WAGR syndrome, bilateral congenital aniridia, pseudophakia OD and glaucoma OD, was referred for a XEN45 gel stent OD. IOP was persistently elevated at 24 mm Hg despite two glaucoma medications. Implantation of the XEN45 gel stent was performed using a transconjunctival ab externo approach. There were no significant intra-or-postoperative adverse events associated with the stent. The patient achieved good IOP-lowering control without glaucoma medications across the 18-month follow-up period.

Conclusions:

A XEN45 stent through a transconjunctival ab externo approach may be an effective surgical intervention in pediatric patients with secondary open-angle glaucoma associated with aniridia and aphakia.

• Authors: Brooklyn Rawlyk, Mitchell D Thatcher, Shehla Rubab, Maria Gabriela Campos-Baniak
• Journal: American journal of ophthalmology case reports (Am J Ophthalmol Case Rep) Vol. 32 Pg. 101888 (Dec 2023) ISSN: 2451-9936 [Electronic] United States
• PMID: 37533700 (Publication Type: Case Reports)
• Copyright: © 2023 The Authors.