[Kimura's disease mimicking primary neoplasm of the parotid gland: A case report].

Abstract

Background:

Kimura's disease is an infrequent inflammatory disorder, of unknown etiology, with few reports outside of Asia. It presents as a nodule or tumor predominantly in the postauricular region, neck and parotid gland. It is histologically characterized by follicular hyperplasia with wellformed mantle zones, preservation of nodal architecture, prominent eosinophilic infiltrate in the germinal centers and interfollicular areas; and associated with elevated levels of IgE and peripheral eosinophilia.

Clinical case:

We present a case of a 23-year-old man from Mexico, he presented with a recurrent tumor in the right parotid gland, previously treated with surgical resection. Imaging studies were performed and a primary neoplasm of the salivary gland was suspected, he was treated with surgical resection. The histological diagnosis was Kimura's disease.

Conclusions:

Communication and divulgation of this rare inflammatory disorder expans the knowledge for the differential diagnosis of tumors of the head and neck, and salivary glands, mainly in men with peripheral eosinophilia and elevated IgE; it can sometimes simulate malignant neoplasms, leads to inadequate diagnostic and therapeutic approaches.

• Authors: Javier Alejandro Teco-Cortes, Juan José Navarrete-Pérez, Oscar Enrique Sánchez-Castro
• Journal: Revista medica del Instituto Mexicano del Seguro Social (Rev Med Inst Mex Seguro Soc) Vol. 60 Issue 4 Pg. 460-465 (Jul 04 2022) ISSN: 2448-5667 [Electronic] Mexico
• Vernacular Title: Enfermedad de Kimura simulando neoplasia primaria de glándula parótida: Reporte de caso.
• PMID: 35819301 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2022 Revista Medica del Instituto Mexicano del Seguro Social.

Chemical References

• Immunoglobulin E

Topics

• Adult
• Angiolymphoid Hyperplasia with Eosinophilia (diagnosis, pathology, surgery)
• Humans
• Immunoglobulin E
• Kimura Disease
• Male
• Neck (pathology)
• Neoplasms
• Parotid Gland (pathology)
• Young Adult