Gd-EOB-DTPA Enhanced MRI Features of Liver Hemangiomatosis Coexistent with GCH.

Abstract

OBJECTIVES:

This study aimed to clarify features of giant cavernous hemangioma (GCH) and liver hemangiomatosis, existing simultaneously on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI).

METHOD:

A total of 17 patients with reported hepatic hemangiomatosis between 2015 and 2017 were identified retrospectively. All our patients underwent pre-contrast MRI, triphasic (atrial, portal, venous) Gd-EOB-DTPA dynamic enhancement and hepatobiliary phase (20 minutes delayed). The location, size, morphology and signal characteristics on T1-weighted (T1WI) and T2-weighted images (T2WI), and Gd-EOB-DTPA-enhanced MRI of liver hemangiomatosis were evaluated.

RESULTS:

Hemangiomatosis involved the liver adjacent to the edge of the GCH with no normal liver tissue found in 13 cases; in the other 4 patients, a small area of normal liver tissue separated GCH from hemangiomatosis was seen. On non-contrast MRI images, hemangionmatosis presented as numerous microcystic lesions, with low signal intensity on T1WI and high signal intensity on T2WI, compared with unaffected liver. After administration of Gd-EOB-DTPA, heterogeneous enhancement was presented in the arterial phase, during portal and venous phase imaging, becoming more homogeneous. 11 cases showed hypointensity in the hepatobiliary phase (6 cases with intratumor necrosis), and 6 cases showed hyper-intensity in the hepatobiliary phase with a remaining unfilled portion.

CONCLUSION:

Hemangiomatosis is extremely rare in the liver adjacent to a GCH. MRI is of great diagnostic and clinical value for this kind of tumor according to the configuration, size, signal, and style of enhancement, but the final diagnosis depends on pathology. Gd-EOB-DTPA-enhanced MRI may help in diagnosing hemangiomatosis coexistent with GCH.

• Authors: Dong Liu, Zhenguo Qiao, Lihua Xu, Fangfang Fu, Aihua Ye, Chunhong Hu
• Journal: Current medical imaging (Curr Med Imaging) Vol. 18 Issue 13 Pg. 1390-1395 ( 2022) ISSN: 1573-4056 [Electronic] United Arab Emirates
• PMID: 35657047 (Publication Type: Journal Article)
• Copyright: Copyright© Bentham Science Publishers; For any queries, please email at [email protected].

Chemical References

• gadolinium ethoxybenzyl DTPA
• Gadolinium
• Contrast Media
• Gadolinium DTPA

Topics

• Humans
• Retrospective Studies
• Gadolinium
• Contrast Media
• Gadolinium DTPA
• Magnetic Resonance Imaging (methods)
• Liver (diagnostic imaging)
• Hemangioma, Cavernous (pathology)