Abstract | BACKGROUND: METHODS: We retrospectively reviewed the records of 310 patients who were diagnosed with colorectal cancer at our hospital and underwent minimally invasive surgery between December 1, 2018, and February 28, 2021. Propensity score matching was conducted with a 1:1 ratio using logistic regression. The primary outcome was the incidence of SSIs in the mini- laparotomy wound. The secondary endpoints were factors affecting the incidence of SSIs. RESULTS: After propensity score matching, 130 patients were assigned to each group. There were no differences in clinical characteristics between the two groups. SSIs occurred in 2 (1.5%) and 3 (2.3%) patients in the gentamicin- collagen sponge and control groups, respectively (p<0.999). The following factors showed a statistically significant association with SSIs: body mass index >25 kg/m2 (odds ratio, 39.0; 95% confidence interval, 1.90-802.21; p = 0.018), liver disease (odds ratio, 254.8; 95% confidence interval, 10.43-6222.61; p = 0.001), and right hemicolectomy (odds ratio, 36.22; 95% confidence interval, 2.37-554.63; p = 0.010). CONCLUSION:
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Authors | Kil-Yong Lee, Jaeim Lee, Youn Young Park, Seong Taek Oh |
Journal | PloS one
(PLoS One)
Vol. 17
Issue 3
Pg. e0264513
( 2022)
ISSN: 1932-6203 [Electronic] United States |
PMID | 35344540
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Gentamicins
- Collagen
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Topics |
- Anti-Bacterial Agents
(therapeutic use)
- Colectomy
(adverse effects)
- Collagen
(therapeutic use)
- Colorectal Neoplasms
(drug therapy, surgery)
- Gentamicins
(therapeutic use)
- Humans
- Minimally Invasive Surgical Procedures
- Propensity Score
- Retrospective Studies
- Risk Factors
- Surgical Wound Infection
(epidemiology)
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