Abstract | INTRODUCTION: PATIENTS AND METHODS: A total of 25 nephrology centres in France participated in the study. All adult non-dialysis chronic kidney disease patients who met the inclusion (GFR>15mL/min/1.73m2) and exclusion criteria and provided consent were systematically recruited over a 4-week inclusion period. Investigators were asked to perform a blood test ( hemoglobin concentration, serum iron, serum ferritin and transferrin saturation) and to complete a questionnaire about their iron status monitoring practices. The primary objective was to assess the prevalence of iron deficiency (serum ferritin<100μg/L and/or transferrin saturation<20%). Secondary objectives were to evaluate the prevalence of absolute iron deficiency (serum ferritin<100μg/L and transferrin saturation<20%) and functional iron deficiency (serum ferritin≥100μg/L and transferrin saturation<20%), the prevalence of iron deficiency according to haemoglobin concentration and chronic kidney disease stage, the proportion of centres that perform routine evaluation of iron status and the number of patients receiving iron supplementation. RESULTS: CONCLUSION: In this observational study, a high prevalence of iron deficiency was observed among non-dialysis chronic kidney disease patients. Less than half of participating centres reported routine assessment of iron status.
|
Authors | Gabriel Choukroun, Isabelle Kazes, Jacques Dantal, Elsa Vabret, Lionel Couzi, Yannick Le Meur, Jean-Noël Trochu, Patrice Cacoub, investigateurs de l’étude CARENFER IRC |
Journal | Nephrologie & therapeutique
(Nephrol Ther)
Vol. 18
Issue 3
Pg. 195-201
(Jun 2022)
ISSN: 1872-9177 [Electronic] France |
Vernacular Title | Prévalence de la carence martiale dans une population de patients insuffisants rénaux chroniques non dialysés : étude nationale multicentrique observationnelle CARENFER. |
PMID | 35241379
(Publication Type: Journal Article, Multicenter Study, Observational Study)
|
Copyright | Copyright © 2022. Published by Elsevier Masson SAS. |
Chemical References |
- Transferrins
- Ferritins
- Iron
|
Topics |
- Adult
- Anemia, Iron-Deficiency
(diagnosis, epidemiology, etiology)
- Ferritins
- Humans
- Iron
- Iron Deficiencies
- Prevalence
- Renal Insufficiency, Chronic
(complications, epidemiology)
- Transferrins
|