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Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-naïve chronic lymphocytic leukemia.

AuthorsJeff P Sharman, Miklos Egyed, Wojciech Jurczak, Alan Skarbnik, John M Pagel, Ian W Flinn, Manali Kamdar, Talha Munir, Renata Walewska, Gillian Corbett, Laura Maria Fogliatto, Yair Herishanu, Versha Banerji, Steven Coutre, George Follows, Patricia Walker, Karin Karlsson, Paolo Ghia, Ann Janssens, Florence Cymbalista, Jennifer A Woyach, Emmanuelle Ferrant, William G Wierda, Veerendra Munugalavadla, Ting Yu, Min Hui Wang, John C Byrd
JournalLeukemia (Leukemia) Vol. 36 Issue 4 Pg. 1171-1175 (04 2022) ISSN: 1476-5551 [Electronic] England
PMID34974526 (Publication Type: Research Support, Non-U.S. Gov't, Letter)
Chemical References
  • Antibodies, Monoclonal, Humanized
  • Benzamides
  • Pyrazines
  • Chlorambucil
  • acalabrutinib
  • obinutuzumab
Topics
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Combined Chemotherapy Protocols (adverse effects)
  • Benzamides
  • Chlorambucil (therapeutic use)
  • Follow-Up Studies
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell (drug therapy)
  • Pyrazines

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