B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)

A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
Also Known As:
Chronic Lymphocytic Leukemia; Lymphoma, Small Cell; Leukemia, B Cell, Chronic; Leukemia, Chronic Lymphoblastic; Leukemia, Chronic Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Diffuse Well-Differentiated Lymphocytic Lymphoma; Leukemia, Lymphoblastic, Chronic; Leukemia, Lymphocytic, Chronic, B Cell; Lymphoblastic Leukemia, Chronic; Lymphocytic Leukemia, Chronic; Lymphocytic Leukemia, Chronic, B Cell; Lymphocytic Lymphoma; Lymphocytic Lymphoma, Diffuse, Well Differentiated; Lymphocytic Lymphoma, Diffuse, Well-Differentiated; Lymphocytic Lymphoma, Well Differentiated; Lymphocytic Lymphoma, Well-Differentiated; Lymphoma, Lymphocytic; Lymphoma, Lymphocytic, Diffuse, Well Differentiated; Lymphoma, Lymphocytic, Diffuse, Well-Differentiated; Lymphoma, Lymphocytic, Well Differentiated; Lymphoma, Lymphocytic, Well-Differentiated; Lymphoma, Lymphoplasmacytoid, CLL; Lymphoma, Small Lymphocytic, Plasmacytoid; Lymphoma, Small-Cell; Lymphoplasmacytoid Lymphoma, CLL; Small-Cell Lymphoma; B Cell Chronic Lymphocytic Leukemia; B Cell Leukemia, Chronic; B Lymphocytic Leukemia, Chronic; B-Cell Leukemias, Chronic; B-Lymphocytic Leukemias, Chronic; CLL Lymphoplasmacytoid Lymphoma; CLL Lymphoplasmacytoid Lymphomas; Chronic B-Cell Leukemia; Chronic B-Cell Leukemias; Chronic B-Lymphocytic Leukemia; Chronic B-Lymphocytic Leukemias; Chronic Lymphoblastic Leukemia; Chronic Lymphoblastic Leukemias; Chronic Lymphocytic Leukemias; Diffuse Well Differentiated Lymphocytic Lymphoma; Leukemia, Chronic B-Cell; Leukemia, Chronic B-Lymphocytic; Leukemias, Chronic B-Cell; Leukemias, Chronic B-Lymphocytic; Leukemias, Chronic Lymphoblastic; Leukemias, Chronic Lymphocytic; Lymphoblastic Leukemias, Chronic; Lymphocytic Leukemias, Chronic; Lymphocytic Lymphoma, Small; Lymphocytic Lymphomas; Lymphocytic Lymphomas, Small; Lymphocytic Lymphomas, Well-Differentiated; Lymphoma, CLL Lymphoplasmacytoid; Lymphoma, Well-Differentiated Lymphocytic; Lymphomas, CLL Lymphoplasmacytoid; Lymphomas, Lymphocytic; Lymphomas, Small Lymphocytic; Lymphomas, Small-Cell; Lymphomas, Well-Differentiated Lymphocytic; Lymphoplasmacytoid Lymphomas, CLL; Small Cell Lymphoma; Small Lymphocytic Lymphoma; Small Lymphocytic Lymphomas; Small-Cell Lymphomas; Well-Differentiated Lymphocytic Lymphoma; Well-Differentiated Lymphocytic Lymphomas; B-Cell Leukemia, Chronic; B-Lymphocytic Leukemia, Chronic; Leukemia, B-Cell, Chronic; Leukemia, Lymphocytic, Chronic; Lymphocytic Leukemia, Chronic, B-Cell; Lymphoma, Small Lymphocytic
Networked: 5913 relevant articles (343 outcomes, 653 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Non-Hodgkin Lymphoma (Lymphosarcoma)
2. Neoplasms (Cancer)
3. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
4. Hairy Cell Leukemia
5. Lymphoma (Lymphomas)


1. Byrd, John C: 123 articles (12/2015 - 02/2002)
2. Keating, Michael J: 102 articles (11/2015 - 02/2002)
3. Kipps, Thomas J: 87 articles (12/2015 - 03/2002)
4. O'Brien, Susan: 76 articles (06/2015 - 02/2002)
5. Robak, Tadeusz: 74 articles (12/2015 - 01/2002)
6. Stilgenbauer, Stephan: 66 articles (12/2015 - 08/2002)
7. Wierda, William G: 63 articles (11/2015 - 06/2003)
8. Hallek, Michael: 62 articles (11/2015 - 01/2002)
9. Ferrajoli, Alessandra: 52 articles (11/2015 - 08/2002)
10. Kay, Neil E: 52 articles (09/2015 - 10/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to B-Cell Chronic Lymphocytic Leukemia:
1. fludarabineIBA
2. rituximab (Mabthera)FDA Link
3. alemtuzumab (Campath)FDA Link
4. Cyclophosphamide (Cytoxan)FDA LinkGeneric
5. Chlorambucil (Leukeran)FDA Link
6. CladribineFDA LinkGeneric
7. purineIBA
8. bendamustineFDA Link
9. Monoclonal AntibodiesIBA
10. lenalidomide (CC 5013)FDA Link

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Immunotherapy
3. Transplants (Transplant)
4. Stem Cell Transplantation
5. Combination Drug Therapy (Combination Chemotherapy)