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afutuzumab
Subscribe to New Research on afutuzumab
anti-CD20 mAb for treating B-cell lymphoid cancers
Also Known As:
GA 101; GA-101; GA101 antibody; R 7159; R-7159; R7159 cpd; RO 5072759; RO-5072759; RO5072759
Networked:
1
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins
Proteins: 90489
Blood Proteins: 4303
Serum Globulins: 75
Immunoglobulins: 23980
Antibodies: 92632
Monoclonal Antibodies: 18549
afutuzumab: 1
Immunoproteins: 33
Immunoglobulins: 23980
Antibodies: 92632
Monoclonal Antibodies: 18549
afutuzumab: 1
Globulins: 334
Serum Globulins: 75
Immunoglobulins: 23980
Antibodies: 92632
Monoclonal Antibodies: 18549
afutuzumab: 1
Experts
1.
Robak, Tadeusz
: 1 article (06/2009)
Related Diseases
1.
Neoplasms (Cancer)
06/01/2009 - "
In preclinical studies, GA-101 was significantly more potent and effective in depleting B-cells than rituximab, and induced dose-dependent antitumor activity, complete tumor regression and improved long-term survival in xenograft mouse models of B-cell malignancy.
"
2.
B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/01/2009 - "
Based on preclinical and preliminary clinical data, GA-101 appears to be a promising therapeutic agent for CD20-positive B-cell lymphoid malignances, including non-Hodgkin lymphomas and chronic lymphocytic leukemia.
"
3.
Lymphoma (Lymphomas)
06/01/2009 - "
Based on preclinical and preliminary clinical data, GA-101 appears to be a promising therapeutic agent for CD20-positive B-cell lymphoid malignances, including non-Hodgkin lymphomas and chronic lymphocytic leukemia.
"
Related Drugs and Biologics
1.
rituximab (Mabthera)
Related Therapies and Procedures
1.
Heterologous Transplantation (Xenotransplantation)