Association of blood glucose level and prognosis of inpatients with coexistent diabetes and COVID-19.

Abstract

Type 2 diabetes (T2D) increases the risk of coronavirus disease (COVID-19). This study investigates the association between glucose control of COVID-19 patients with T2D in first 7 days after hospital admission and prognosis. A total of 252 infected inpatients with T2D in China were included. Well-controlled blood glucose was defined as stable fasting blood glucose (FBG) levels in the range of 3.9-7.8 mmol/L during first 7 days using indicators of average (FBGA), maximum (FBGM) or first-time (FBG1) FBG levels. The primary endpoint was admission to intensive care unit or death. Hazard ratio (HR) of poorly controlled glucose level group compared with well-controlled group were 4.96 (P = 0.021) for FBGM and 5.55 (P = 0.014) for FBGA. Well-controlled blood glucose levels in first 7 days could improve the prognosis of COVID-19 inpatients with diabetes.

• Authors: Weiwei Duan, Liangyu Li, Xuesong Li, Mengyan Zhu, Lingxiang Wu, Wei Wu, Kening Li, Yuan Liang, Rong Ding, Wenhua You, Ziyu Wang, Bin Huang, Min Wu, Tingting Zhang, Jie Li, Yan Li, Jiaofang Shao, Changsong Lin, Pengping Li, Qianghu Wang, Shukui Wang, Xinyi Xia, Yu Liu, Sali Lyu
• Journal: Endocrine (Endocrine) Vol. 75 Issue 1 Pg. 1-9 (01 2022) ISSN: 1559-0100 [Electronic] United States
• PMID: 34716852 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Chemical References

• Blood Glucose

Topics

• Blood Glucose
• COVID-19
• Diabetes Mellitus, Type 2 (complications)
• Humans
• Inpatients
• Prognosis
• Retrospective Studies
• Risk Factors
• SARS-CoV-2