Objective: To analyze the prevalence trends and related factors of
hypertension patients complicating with
dyslipidemia in community. Methods: This was a cross-sectional survey, patients with
hypertension were selected from the different communities of Guangdong province in 2013 and 2018 respectively. General clinical characteristics, including demographic information, past history, family history, and medication history, were collected.
Dyslipidemia was defined as follows: at least 1 item elevation of total
cholesterol (TC)≥5.2 mmol/L,
triglyceride (TG) ≥1.7 mmol/L,
low-density lipoprotein cholesterol (LDL-C)≥3.4 mmol/L, or reduced
high-density lipoprotein cholesterol (HDL-C)<1.0 mmol/L. The incidence of
dyslipidemia was standardized based on the 2010 China Census data, and further subgroup analysis was performed according to age (<50, 50-60, ≥60 years old) and sex (male, female). Multivariate logistic regression was used to analyze the related factors of
dyslipidemia. Results: In 2013 and 2018, 7 866 (4 148 (52.7%) females, with the age of (62.4±13.6) years) and 11 611 (6 692 (57.6%) females, with the age of (58.2±9.3)years) patients with
hypertension were enrolled for data analysis, respectively. In 2013, the total prevalence rate of
dyslipidemia in patients with
hypertension in the community of Guangdong province was 56.3%, among which the prevalence rates of
hypercholesterolemia,
hypertriglyceridemia, high
LDL-Cemia, and low HDL-Cemia were 17.1. %, 21.3%, 2.3% and 24.4%, respectively. The total prevalence of
dyslipidemia in patients with
hypertension in the community of Guangdong in 2018 was 47.3%, prevalence of
hypercholesterolemia,
hypertriglyceridemia, high
LDL-Cemia and low HDL-Cemia was 14.1%, 20.3%, 12.0% and 19.4%, respectively. Subgroup analysis showed that the total prevalence of
dyslipidemia in male patients with
hypertension in the community of Guangdong in 2013 and 2018 was 59.0% and 50.7%, respectively, among which
hypercholesterolemia was 13.8% and 8.0%, and
hypertriglyceridemia was 22.3%, 20.9%, high
LDL-Cemia was 1.7%, 8.1%, low HDL-Cemia was 32.9%, 30.3%, respectively. In 2013 and 2018, the total prevalence of
dyslipidemia in female patients with
hypertension in the community of Guangdong province was 53.9% and 44.8%, among which prevalence of
hypercholesterolemia was 20.5% and 18.5%,
hypertriglyceridemia was 20.4% and 19.8%, and high
LDL-Cemia was 2.7% and 14.9%, and hypo-HDL-Cemia was 16.8% and 11.3%, respectively. Age subgroup analysis showed that the prevalence of
dyslipidemia among hypertensive patients aged<50, 50-60, and ≥60 years in Guangdong community in 2013 were 60.1%, 60.6%, and 53.7%, respectively; and 46.2%, 49.3% and 46.5% in 2018, respectively. Multivariate logistic regression analysis showed that women (OR=0.860,95%CI 0.761-0.973,P=0.017), obese (OR=2.295,95%CI 2.007-2.624,P<0.001), diabetes (OR=1.314,95%CI 1.090-1.583,P=0.004),
stroke (OR=1.894,95%CI 1.227-2.924,P=0.004) and the level of fasting
blood glucose (OR=1.105,95%CI 1.066-1.146,P<0.001) were independently related with the occurrence of
dyslipidemia. Conclusions: The prevalence of
dyslipidemia in patients with
hypertension in the communities of Guangdong province is relatively high, and the prevalence differs in sex and age. Between 2013 and 2018, the total prevalence of
dyslipidemia, hyper-TCemia, and hypo-HDL-Cemia in hypertensive patients shows a downward trend. The prevalence of hyper-TGemia remains unchanged, but the prevalence of high
LDL-C shows an upward trend. Several factors are related to the prevalence of dislipidemia in
hypertension patients in Guandong community.