Abstract | BACKGROUND: OBJECTIVE: To determine the incidence and severity of CMIHR in all subtypes of SM. METHODS: RESULTS: Previous CMIHRs to CT ( vomiting, n = 1, erythema, n = 1, cardiovascular shock, n = 1), and MRI ( dyspnea, n = 1, cardiovascular shock, n = 1) had been reported by 4 out of 162 (2.5%) patients (ISM, n = 3; advSM, n = 1). In contrast, during or after 332 CM-enhanced CT or MRI examinations at our institution, no CMIHRs were reported. Premedication was solely given to 3 patients before CT scans, including 1 with previous CMIHR, who tolerated the imaging well. CONCLUSION: We conclude that: (1) there is a substantial discrepancy between the perception and prevalence of HRs to CM in SM; (2) reactions are scarce in ISM and even rarer in advSM; and (3) in SM patients without previous history of CM hypersensitivity, prophylactic premedication before CM-enhanced CT or MRI is dispensable.
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Authors | Juliana Schwaab, Knut Brockow, Philipp Riffel, Johannes Lübke, Nicole Naumann, Mohamad Jawhar, Lukas Reiter, Alice Fabarius, Georgia Metzgeroth, Stefan O Schoenberg, Wolf-Karsten Hofmann, Andreas Reiter, Julia Riffel |
Journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
(Ann Allergy Asthma Immunol)
Vol. 128
Issue 3
Pg. 314-318
(03 2022)
ISSN: 1534-4436 [Electronic] United States |
PMID | 34637924
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2021 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Arthropod Venoms
- Contrast Media
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Topics |
- Adult
- Arthropod Venoms
- Contrast Media
(adverse effects)
- Humans
- Magnetic Resonance Imaging
- Mastocytosis
- Mastocytosis, Systemic
- Retrospective Studies
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